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Professor John Reynolds

Professor & Head of Department (Surgery)


  Anti-oxidants in inflammatory disease   Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus   Liver and gut immune function in patients undergoing complex major surgery   Molecular predictors of response and resistance to chemotherapy and radiation therapy   Transcription factors in inflammation and neoplasia of the oesophagus   Upper gastrointestinal physiology
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Member, DMMC Inflammation, Immunity & Infection Principal Investigators, DMMC Principal Investigators leading research in inflammation, immunit and infection.
Member, Centre for Molecular Research in Cancer (Proposed), This consortium combines researchers with common interest in understanding cell cycle signaling and regulation with specific focus on two key cancer-related processes (cell cycle control, apoptosis) and/or three specific malignancy types (oesophageal, prostate and haematological).
Member, Colorectal & GI Cancer Research Group (Proposed), Speculative idea to cluster PI's around collaborative study on Upper GI and Colon Cancers.Deliberately wide selection of surgeons, pathologists and academic researchers based on stated interest or publication in fields of oesophageal or colorectal cancer.
Member, PHG Funded PI's and Researchers, All Researchers funded under Cycle 3 PRTLI - Programme for Human Genomics
Reynolds, J.V. and Donachie, V. and Marron, J. and Shevlin, A., Management of locally advanced adenocarcinoma of the oesophagus and oesophagogastric junction: the Neo-AEGIS trial â€" Authors' reply, The Lancet Gastroenterology and Hepatology, 9, (2), 2024, p104-105 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
O'Neill, S. and Deegan, J. and Ramjit, S. and Reynolds, J.V. and Donohoe, C.L., â€~SurgTalk†: The Educational Outcomes Associated With Development of a Surgical Podcast for Undergraduate Medical Students, Journal of Surgical Education, 81, (2), 2024, p202-209 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Fanning M, Murphy CF, Elliott JA, Ravi N, Docherty NG, le Roux CW, Donohoe CL, Reynolds JV., Continuous glucose monitoring and low-glycaemic index diet in the management of postprandial hypoglycaemia after oesophagogastric cancer surgery., The British journal of surgery, 111, (1), 2024, pznad371 , Journal Article, PUBLISHED  DOI
Bennett, A.E., O'Neill, L., Doyle, S.L., Guinan, E.M., O'Sullivan, J., Reynolds, J.V., Hussey, J., Nutrient Intakes and Gastrointestinal Symptoms Among Esophagogastric Cancer Survivors up to 5 Years Post-Surgery, Nutrition and Cancer, 2024, p1-10 , Journal Article, PUBLISHED  DOI  URL
Kampan, N.C. and Kartikasari, A.E.R. and Deceneux, C. and Madondo, M.T. and McNally, O.M. and Flanagan, K.L. and Aziz, N.A. and Stephens, A.N. and Reynolds, J. and Quinn, M.A. and Plebanski, M., Combining TNFR2-Expressing Tregs and IL-6 as Superior Diagnostic Biomarkers for High-Grade Serous Ovarian Cancer Masses, Cancers, 15, (3), 2023, Notes: [cited By 0], Journal Article, PUBLISHED  DOI
McDonnell, S. and Breslin, T. and Mascan, B. and Shahruddin, N.S. and Elnour, M. and Fanning, M. and Galvin, A. and Moore, J. and Ravi, N. and Reynolds, J.V. and Donohoe, C.L., Translating evidence in a priority setting partnership: knowledge gaps between healthcare providers and oesophageal cancer patients, Supportive Care in Cancer, 31, (2), 2023, Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Davern, M. and Bracken-Clarke, D. and Donlon, N.E. and Sheppard, A.D. and Connell, F.O. and Heeran, A.B. and Majcher, K. and Conroy, M.J. and Mylod, E. and Butler, C. and Donohoe, C. and Donnell, D.O. and Lowery, M. and Bhardwaj, A. and Ravi, N. and Melo, A.A. and Sullivan, J.O. and Reynolds, J.V. and Lysaght, J., Visceral adipose tissue secretome from early and late-stage oesophageal cancer patients differentially affects effector and regulatory T cells, Journal of Cancer Research and Clinical Oncology, 2023, Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Davern M, Donlon NE, O'Connell F, Gaughan C, O'Donovan C, Habash M, Sheppard AD, MacLean M, Dunne MR, Moore J, Temperley H, Conroy MJ, Butler C, Bhardwaj A, Ravi N, Donohoe CL, Reynolds JV, Lysaght J., Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients, Cancer Immunology Immunotherapy, 2023, Journal Article, PUBLISHED  TARA - Full Text  DOI
O'Brien, A., Brennan, L., O'Neill, L, Guinan, E., Connolly, D., Reynolds, JV., and Hussey, J., Patient Experiences of a Telehealth Multidisciplinary Cancer Rehabilitation Programme: Qualitative Findings from the ReStOre@Home Feasibility Study, 2023, Journal Article, PUBLISHED  DOI
Reynolds, J.V., Neoadjuvant chemoradiation versus perioperative chemotherapy for oeosphageal adenocarcinoma, British Journal of Surgery, 110, (12), 2023, p1681-1682 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
  

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Cliona M Lorton, John V Reynolds, Joanne Lysaght, ASO Author Reflections: Can CRP and CRP-Based Scores Predict Survival in Operable Adenocarcinomas of the Esophagus and Esophago-Gastric Junction?, Annals of Surgical Oncology, 2021, Journal Article, PUBLISHED

  

Anti-oxidants in inflammatory disease. Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus. Liver and gut immune function in patients undergoing complex major surgery. Molecular predictors of response and resistance to chemotherapy and radiation therapy. Transcription factors in inflammation and neoplasia of the oesophagus. Upper gastrointestinal physiology.