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Trinity College Dublin

Personal Information
Name Reynolds, John
Main Department Surgery
College Title Professor & Head of Department
E-mail reynoljv@tcd.ie
College Tel +353 1 896 2189
Web http://people.tcd.ie/reynoljv
 
Representations
Details Date
Member, DMMC Inflammation, Immunity & Infection Principal Investigators, DMMC Principal Investigators leading research in inflammation, immunit and infection.
Member, Centre for Molecular Research in Cancer (Proposed), This consortium combines researchers with common interest in understanding cell cycle signaling and regulation with specific focus on two key cancer-related processes (cell cycle control, apoptosis) and/or three specific malignancy types (oesophageal, prostate and haematological).
Member, Colorectal & GI Cancer Research Group (Proposed), Speculative idea to cluster PI's around collaborative study on Upper GI and Colon Cancers.Deliberately wide selection of surgeons, pathologists and academic researchers based on stated interest or publication in fields of oesophageal or colorectal cancer.
Member, PHG Funded PI's and Researchers, All Researchers funded under Cycle 3 PRTLI - Programme for Human Genomics
 
Description of Research Interests
Anti-oxidants in inflammatory disease. Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus. Liver and gut immune function in patients undergoing complex major surgery. Molecular predictors of response and resistance to chemotherapy and radiation therapy. Transcription factors in inflammation and neoplasia of the oesophagus. Upper gastrointestinal physiology.
 
Research Interests
Anti-oxidants in inflammatory disease Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus Liver and gut immune function in patients undergoing complex major surgery Molecular predictors of response and resistance to chemotherapy and radiation therapy
Transcription factors in inflammation and neoplasia of the oesophagus Upper gastrointestinal physiology
 
Publications and Other Research Outputs
Peer Reviewed
Smith FM, Gallagher WM, Fox E, Stephens RB, Rexhepaj E, Petricoin EF 3rd, Liotta L, Kennedy MJ, Reynolds JV, Combination of SELDI-TOF-MS and data mining provides early-stage response prediction for rectal tumors undergoing multimodal neoadjuvant therapy, Annals of Surgery, 245, (2), 2007, p259 - 266
URL
J. M. O'Riordan, O. N. Tucker, P. J. Byrne, G. S. McDonald, N. Ravi, P. W. Keeling and J. V. Reynolds, Factors influencing the development of Barrett's epithelium in the esophageal remnant postesophagectomy, The American journal of gastroenterology, 99, (2), 2004, p205-11
URL
J. M. O'Riordan, P. J. Byrne, N. Ravi, P. W. Keeling and J. V. Reynolds, Long-term clinical and pathologic response of Barrett's esophagus after antireflux surgery, American journal of surgery, 188, (1), 2004, p27-33
URL
M. M. Abdel-Latif, J. O'Riordan, H. J. Windle, E. Carton, N. Ravi, D. Kelleher and J. V. Reynolds, NF-kappaB Activation in Esophageal Adenocarcinoma: Relationship to Barrett's Metaplasia, Survival, and Response to Neoadjuvant Chemoradiotherapy, Annals of surgery, 239, (4), 2004, p491-500
URL
J. V. Reynolds, K. Walsh, J. Ruigrok and J. M. Hyland, Randomised comparison of silicone versus Teflon cannulas for peripheral intravenous nutrition, Annals of the Royal College of Surgeons of England, 77, (6), 1995, p447-9
URL
More Publications and Other Research Outputs >>>
 

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Last Updated:18-APR-2014