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Professor Charles Dorman

Professor (Microbiology)


Charles J Dorman is the Professor of Microbiology at Trinity College Dublin. He is a microbial geneticist and has held the Established Chair of Microbiology at Trinity College Dublin since 1994. Professor Dorman was an elected Council Member and Trustee of the Microbiology Society and was Council's representative on its Policy Committee until Dec 2020. He was also a Science Foundation Ireland Principal Investigator from 2003-2021, is a Founding Member of the European Academy of Microbiology, a Fellow of the American Academy of Microbiology, a Member of the Royal Irish Academy (Ireland's highest academic honour), a Fellow of the Royal Society of Biology and was made a Chartered Biologist by the Institute of Biology in 2009. He is a recipient of the Fleming Prize of the Society for General Microbiology (SGM) and was formerly a Royal Society Research Fellow and Lecturer in Biochemistry at the Medical Sciences Institute at Dundee University in the United Kingdom. Professor Dorman was the Ambassador to Western Europe and Israel of the American Society for Microbiology (ASM), has been a member of the ASM Committee on Global Engagement (2014-17) and held a visiting professorship in microbiology and cell biology at the Indian Institute of Science at Bangalore (2014-17). Dorman has delivered more than 200 invited lectures at conferences, universities and research institutes around the world over the past thirty-three years. From 2005 to 2010, he was the Editor-in-Chief of 'Microbiology' (published by the SGM) and from 2014 to 2017 chaired the Microbiology Society's Publishing committee with responsibility for its six scientific journals. He has served on the editorial boards of fifteen scientific journals and has been an advisor to national and international research funding agencies worldwide. For many years he was an international (i.e. non-UK) member of the committees of the UK's Biotechnology and Biological Sciences Research Council (BBSRC) and has chaired an influential review of all microbial science in the UK on behalf of the BBSRC. Recently (2018-20), he chaired the 'State of Microbiology' review panel at the Microbiology Society, assessing the health of the discipline in the UK and Ireland. He has also served on the International Scientific Committee of the Institute of Bioengineering (IBEC) in Barcelona, advising IBEC on its scientific strategy. Charles Dorman's own research focuses on the global regulation of gene expression in bacteria of medical importance, with an emphasis on the regulatory roles of DNA topology and nucleoid-associated proteins.
  BACTERIA   BACTERIAL   BACTERIAL GENE   BACTERIUM   BINDING-PROTEINS   BINDING-SITE   BINDING-SITES   BIOCHEMICAL   BIOCHEMICAL APPROACH   BIOCHEMISTRY   BIOLOGY   CURVED DNA   DEOXYRIBONUCLEIC-ACID GYRASE   DNA   DNA ARRAY   DNA BENDING   DNA BINDING   DNA GYRASE   DNA INVERSION   DNA MICROARRAYS   DNA RECOGNITION DOMAINS   DNA SUPERCOILING   DNA SUPERHELICITY   DNA TOPOLOGY   DNA-BINDING   DNA-BINDING ACTIVITY   DNA-BINDING DOMAIN   DNA-BINDING DOMAINS   DNA-BINDING PROTEIN   DNA-BINDING PROTEINS   DNA-BINDING SUBUNIT   ENVIRONMENTAL REGULATION   ENVIRONMENTAL-REGULATION   ESCHERICHIA-COLI K-12   FIMBRIAE   FIMBRIAL PHASE VARIATION   FIS PROTEIN   GENE REARRANGEMENTS   GENE REGULATION   GENE-EXPRESSION   GENES   GENETIC   GENETIC MANIPULATION   GENETIC STRUCTURE   GENETIC-ANALYSIS   GENETICS   GENOME   GENOME COMPACTION   GENOME EVOLUTION   GENOME EXPRESSION ANALYSIS   GENOMES   GENOMIC ORGANIZATION   GENOMICS   GLOBAL REGULATOR   GROWTH-PHASE CONTROL   GROWTH-PHASE REGULATION   HISTONE-LIKE PROTEINS   HNS   H-NS   INTEGRATION HOST FACTOR   MESSENGER-RNA   MICROARRAY   MICROARRAY DATA   MICROBIAL ACTIVITY   MICROBIOLOGY   MICROORGANISM   MICROORGANISMS   MOLECULAR-BIOLOGY   MOLECULAR-CLONING   MOLECULAR-GENETICS   MOLECULAR-STRUCTURE   SALMONELLA-TYPHIMURIUM   SHIGELLA-FLEXNERI   SITE-SPECIFIC RECOMBINASES   TRANSCRIPTIONAL ACTIVATION   TYPE-1 FIMBRIAE
 Bacterial gene regulation by DNA supercoiling.
 Bacterial DNA supercoiling and gene regulation.
 DNA supercoiling, gene expression and bacterial pathogenicity.
 Contribution of DNA topology to the control of virulence gene expression in Shigella flexneri.
 Environmental stress, DNA supercoiling and the regulation of virulence in Salmonella typhimurium.

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Details Date
Holder of Established Chair of Microbiology (formerly the Chair of Bacteriology and Preventive Medicine, established 1919), Trinity College Dublin Since 1994
Head of Microbiology Department, Moyne Institute of Preventive Medicine, Trinity College Dublin 1994-2001; 2013-2014; 2020-2021
Head, School of Genetics and Microbiology, TCD 2008-2011; 2014-2017; 2017-2018
Science Foundation Ireland Principal Investigator 2003-2021
Elected member of Council and Trustee, Microbiology Society, Charles Darwin House, London, UK 2019-2020
Chair, State of Microbiology in the UK and Ireland Review Panel, Microbiology Society, Charles Darwin House, London, UK 2018-2020
Council representative on Impact and Influence committee, Microbiology Society, London, UK 2020-2020
Council representative on the Policy committee of the Microbiology Society, Charles Darwin House, London, UK 2019-2020
Guest editor, Current Opinion in Microbiology, published by Elsevier, Park Avenue, New York, USA 2019-2020
Member, Evaluation Commission of CERCA (Research Centres Institution of Catalonia) Spain 2018
Ireland representative, Management Committee of European Topology Interdisciplinary COST Action (EUTOPIA) 2018-2022
Trustee and Member of Council (governing body) of the Microbiology Society, Charles Darwin House, London, UK 2015-2017
Visiting Professor, Department of Microbiology and Cell Biology, Indian Institute of Science, Bangalore, India 2014-2017
Chair, Publications Committee, Microbiology Society, Charles Darwin House, London, UK 2015-2018
Member, European Research Council (ERC) Advanced Grant genomics panel LS2, Brussels, Belgium. 2015-2016
Member, Committee on Global Engagement, American Society for Microbiology, Washington DC, USA 2012-2017
Member, International Scientific Committee, IBEC Foundation (Bio-engineering Institute of Catalonia), Barcelona University, Spain 2014-2020
International supervisor, Masters degree in Life Sciences and Technology, Leiden University, The Netherlands 2016-2017
European Ambassador of the American Society for Microbiology, Washington DC, USA 2010-2013
Chair, AERES/HCERES (French Higher Education Authority agency) research assessment visiting group, INSERM UMR 5240, University Claude Bernard, Lyon, France 2014-2015
International Working Group, Microbiology Society, London, UK 2015
Equality and Diversity Ambassador, Microbiology Society, London, UK 2015-2017
Representative of the American Society for Microbiology at the 5th Congress of European Microbiology Societies, Leipzig, Germany 2013
Nomination Committee, American Academy of Microbiology's Moselio Schaechter Distinguished Service Award, Washington DC, USA 2010-2011
Assessment Committee, Heatley-Payne Exchange Program for Early Career Scientists (American Society for Microbiology and the Microbiology Society) 2010-2014
Selection Committee, American Academy of Microbiology, GSK International Member of the Year Award, Washington DC, USA 2011-2015
Award Committee, American Society for Microbiology and Federation of European Microbiology Mäkelä - Cassell Award 2012-2015
Chairman, BBSRC Strategic Review of United Kingdom (UK) Microbial Science 2005-2006
Editor-in-Chief, Microbiology (Published by the Society for General Microbiology) 2005-2010
International Advisory Committee, International Union of Microbiological Societies (IUMS) Congress 2011, Sapporo, Japan 2011
Faculty Opinions (Faculty member) Since 2020
Faculty of 1000 (Faculty Prime member) 2006-2020
Editorial Advisory Board, Molecular Microbiology, published by Wiley-Blackwell, Oxford, UK Since 2005
Editorial Board, Journal of Bacteriology, published by the American Society of Microbiology, Washington DC, USA 2007-2018
Editorial Board, microLife, published by Oxford University Press on behalf of the European Academy of Microbiology since 2020
Editorial Board, Journal of Molecular Microbiology and Biotechnology, published by Karger, Basel, Switzerland 1998-2020
Editorial Board, International Journal of Medical Microbiology, published by Elsevier, Park Avenue, New York, USA 1999-2007
Editorial Advisory Board, Biochemical Journal (Biochemical Society Journal), published by Portland Press, London, UK 1996-2008
Guest Editor, mBio various
Editorial Board, Pathogens and Disease, published by John Wiley and Sons, Hoboken, New Jersey, USA Since 2013
Associate Editor, PLoS Pathogens, published by the Public Library of Science, Cambridge, UK 2013
Editorial Board, Microbial Physiology Since 2020
Editorial board, Biomedicine Hub Since 2016
Associate Editor, PLoS Genetics, published by the Public Library of Science, Cambridge, UK 2013
Guest Editor, Current Opinion in Microbiology, published by Elsevier, Park Avenue, New York, USA 2008-2009
Associate Editor, Microbiology (Published by the Society for General Microbiology, Reading, UK) 1993-1998
Senior Editor, Microbiology (Published by the Society for General Microbiology, Reading, UK) 1998-2003
Organizer, American Society for Microbiology Symposium "Complex Genetic Switches" at the 4th Congress of the Federation of European Microbiological Societies, Geneva, Switzerland 2010-2011
Vice-President, Euroconference series on Bacterial Neural Networks, Strasbourg, France 2002
President, Euroconference on Intracellular Signalling and Global Regulation, Killiney, Ireland 2000
Trustee and Council Member, Society for General Microbiology, Marlborough House, Reading, UK 2005-2009
SGM Journals Business Sub-Committee 2011-2012
SGM Policy Working Party 2011-2012
SGM Council Liaison Officer, SGM Irish Branch 2005-2009
Member, SGM Treasurer's Committee 2005-2010; 2011-2012
SGM Strategy Group 2006
Scientific Advisory Board international member, Veterinary Training and Research Initiative, Bristol University (DEFRA, HM Government, UK) 2005-2009
Academy of Finland, Research Council for Bioscience and Environment, Biosciences Panel, Helsinki, Finland 2004-2006
Co-organizer, American Society for Microbiology Colloquium on H-NS, Boston, USA 2008
Health Research Board of Ireland, Microbiology Committee 1995-98, 1998-00
BBSRC (UK) International member, Plant and Microbial Sciences Research Committee 1995-1997
BBSRC (UK) International member, Initiative on Investigating Gene Function - E. coli Bid: member of prefunding steering committee 1999
BBSRC/NERC (UK) International member, Joint Initiative on Gene Flow in Plants and Microorganisms - member of expert panel 2000
BBSRC (UK) Research Institutes Assessment Exercise: visiting group international member (Institute for Food Research [IFR] Norwich; Institute for Animal Health [IAH] Compton, Edinburgh, Pirbright) 2001, 2006
BBSRC funding initiative on Prokaryotic Responses to Environmental Stress - steering committee international member 1997-1998
Organizer, 2nd European Microbiology Congress: Systems Microbiology Symposium: Madrid, Spain 2006
Organizer, SGM Conference "Fifty Years of the Double Helix": Manchester, UK 2003
Organizer, Royal Irish Academy Seminar on Microbial Responses to Stress 1998
Organizer, Royal Irish Academy Seminar on Biotechnology 1999
Ireland representative at Scientia Europeae (French Academy of Science) 1997
Co-organizer (with Harry Smith FRS), Royal Society Discussion Meeting on Bacterial Pathogens In Vivo: Royal Society Hook Committee, Carlton House Terrace, London, UK 1999
Co-organizer (with Harry Smith FRS), Novartis Foundation Conference on Bacterial Pathogens In Vivo, Portland Place, London UK 1999
PhD examiner University of Birmingham, University of Cambridge, University of Dublin, University of Dundee, University of East Anglia, University of Edinburgh, University of Leicester, Manipal University India, University of Nottingham, The National University of Ireland, The John Innes Centre, The Institute for Food Research UK, Imperial College London, University College London; Vrije Universiteit Amsterdam; Wellcome Trust Sanger Institute, Cambridge; Indian Institute of Science, Bangalore Since 1988
External advisor appointments and promotions committees at Institute Pasteur, France; University of Bath, University of Birmingham, University College Cork, University College Dublin, University of Dundee, University of Edinburgh, University of Galway, University of Helsinki, Finland; National Centre for Biological Science, Bangalore, India; New York State Department of Health, USA; University of Sheffield; University of East Anglia; Sultan Qaboos University, Muscat, Oman; University of North Carolina at Chapel Hill, USA; University of Houston, Texas, USA; Indian Institute for Science, Bangalore, India; Harvard University, Boston, USA Since 1988
Ad hoc grant reviewer for: Agriculture and Food Research Council (UK), Austrian Science Fund, Biomedical Research Council (Singapore), Biotechnology and Biological Sciences Research Council (UK), Crumlin Hospital Children's Research Centre (Ireland), Danish Council for Independent Research, DFF (Denmark), Deutsche Forschungsgemeinschaft (Germany), Federal Ministry of Education and Research (Germany), Fundação para a Ciência e a Tecnologia, I.P. (Portugal), Health and Medical Research Fund (Hong Kong), Health Research Board (Ireland), Human Frontier Science Program, Istituto Pasteur-Fondazione Cenci Bolognetti (Italy), Israel Science Foundation (ISF), Labex Jury, French National Research Agency ANR (France), Leverhulme Trust (UK), Medical Research Council (Canada), Medical Research Council (UK), National Science Foundation (USA), Natural Environment Research Council (UK), Netherlands Organization for Scientific Research, Since 1988
Ad hoc grant reviewer for (contd): Pasteur Institute Fundamental North Atlantic Treaty Organization (NATO), Nuffield Trust (UK), Research Programme (France), Royal Society (UK), Science and Engineering Research Council (UK), Science Foundation Ireland, Swiss National Science Foundation (SNF), Third World Academy of Science (TWAS), United Nations (UNIDO/ICGEB), US-Israel Agricultural Research & Development Fund (USA-Israel), Wellcome Trust (UK), Wellcome DBT (India). Since 1988
Ad hoc journal referee for 107 international journals/publishers: Annual Review and Research in Biology, Antonie van Leeuwenhoek, Biochemical Society Transactions, Biochim Biophys Acta, Biochimie, BMC Genetics, BMC Genomics, BMC Microbiology, British Microbiology Research Journal, Cell Systems, Cell Reports, Cellular Microbiology, Cellular and Molecular Life Sciences, Computational Biology and Chemistry, Computational and Structural Biotechnology Journal, Current Biology, Current Genetics, DNA Repair, Electrophoresis, EMBO Journal, EMBO Reports, Endeavour, Environmental Microbiology, Essays in Biochemistry, FEBS Lett, FEMS Lett, Food Research International, Functional & Integrative Genomics, G3: Genes Genomes Genetics, Gene Regulation and Systems Biology, Genes and Development, Genes and Function, Genetics, Genetic Research, Heredity, Infection Genetics and Evolution, Infection and Immunity, International Journal of Evolutionary Biology, iScience Since 1988
Ad hoc journal referee for (continued): Journal of Bacteriology, Journal of Basic Microbiology, Journal of Biological Chemistry, Journal of the Royal Society Interface, Journal of Biosciences, Journal of Biotechnology, Journal of Clinical Microbiology, Journal of General Microbiology, Journal of Medical Microbiology, Journal of Molecular Biology, Journal of Molecular Biology and Biotechnology, Journal of Molecular Evolution, Journal of Structural Biology, JoVE, mBio, Microbes and Infection, Microbial Drug Resistance, Microbial Pathogenesis, Molecular and General Genetics, Molecular Biosystems, Molecular Microbiology, Microbiology, Microbiology Today, mSphere, mSystems, Nature, Nature Methods, Nature Microbiology, Nature Reviews Microbiology, Nature Structural and Molecular Biology, Nucleic Acids Research, Open Life Sciences, Philos Trans R Soc Lond B Biol Sci., Physica Scripta, Physical Biology, Plasmid, PLoS Biology, PLoS Genetics, PLoS One, PLoS Pathogens. Since 1988
Ad hoc journal referee for (continued): Proceedings of the National Academy of Sciences USA, Protein Science, Science, ScienceAdvances, Scientific Reports, Soft Matter, Toxins, Transcription, Trends in Genetics, Trends in Microbiology, Vaccine, Veterinary Microbiology, Virulence, Wiley-Blackwell book proposals. Since 1988
Details Date From Date To
European Academy of Microbiology (Founding Member) Since 2009
American Academy of Microbiology (Fellow) Since 2010
Royal Irish Academy (Member) Since 2005
Royal Society of Biology (Fellow) Since 2009
Institute of Biology (Chartered Biologist) 2009 2018
Dublin Academy of Pathogenomics and Infection, DAPI (Founding President) Since 2009
Faculty Opinions Since 2020
Faculty of 1000 (Faculty Member) 2006 2020
Member of the National Commission for Microbiology, Royal Irish Academy 1995 1999
Microbiology Society (formerly Society for General Microbiology) Since 1982
American Society for Microbiology Since 1985
Royal Society Alumnus Group Since 2000
Stochastic modelling of gene regulation in prokaryotes (StoMP Group) Since 2007
Biochemical Society 1988 2008
Society for Experimental Biology 2013 2014
Organization of the Bacterial Nucleoid in, J Jez (editor) , Encyclopaedia of Biological Chemistry 3rd Edition, Volume 5, Oxford, Elsevier, 2021, pp409 - 414, [Dorman CJ], Notes: [Published 2 August 2021], Book Chapter, PUBLISHED  DOI  URL
Gene regulatory networks and hierarchies in bacterial pathogens in, editor(s)Y-W Tang, M Hindiyeh, D Liu, A Sails, P Spearman, J Zhang , Molecular Medical Microbiology 3rd Edition , Amsterdam, Elsevier, 2021, [Dorman CJ], Notes: [Published 1 September 2021], Book Chapter, IN_PRESS  URL
Regulatory hierarchies controlling virulence gene expression in Shigella flexneri and Vibrio cholerae in, editor(s)Zhou D, Wang S, Shen X , Regulation of Gene Expression in Enteropathogenic Bacteria, Vol II, Lausanne, Switzerland, Frontiers, 2021, pp382 - 402, [Dorman MJ, Dorman CJ], Book Chapter, PUBLISHED  URL
Pozdeev G, Mogre A, Dorman CJ, Consequences of producing DNA gyrase from a synthetic gyrBA operon in Salmonella enterica serovar Typhimurium, Molecular Microbiology, 115, (6), 2021, p1410 - 1429, Notes: [Published online 4.02.2021], Journal Article, PUBLISHED  TARA - Full Text  DOI
Dorman, CJ, Structure and Function of the Bacterial Genome, Hoboken, NJ, USA, John Wiley and Sons, 2020, 1 - 418pp, Notes: [Published online February 14 2020; Print publication date: April 21 2020], Book, PUBLISHED  URL
Index in, editor(s)Dorman, CJ , Structure and Function of the Bacterial Genome, Hoboken, NJ, USA, John Wiley and Sons, 2020, pp379 - 395, [Dorman, CJ], Notes: [Published online 14 February 2020], Book Chapter, PUBLISHED  DOI  URL
References. in, editor(s)Dorman, CJ , Structure and Function of the Bacterial Genome, Hoboken, NJ, USA, John Wiley and Sons, 2020, pp247 - 378, [Dorman, CJ], Notes: [Published online 14 February 2020], Book Chapter, PUBLISHED  DOI  URL
An Integrated View of Genome Structure and Function. in, editor(s)Dorman, CJ , Structure and Function of the Bacterial Genome, Hoboken, NJ, USA, John Wiley and Sons, 2020, pp231 - 245, [Dorman, CJ], Notes: [Published online 14 February 2020], Book Chapter, PUBLISHED  DOI  URL
Gene Control: Global Regulation by H-NS. in, editor(s)Dorman, CJ , Structure and Function of the Bacterial Genome, Hoboken, NJ, USA, John Wiley and Sons, 2020, pp211 - 229, [Dorman, CJ], Notes: [Published online 14 February 2020], Book Chapter, PUBLISHED  DOI  URL
Gene Control and Bacterial Physiology. in, editor(s)Dorman, CJ , Structure and Function of the Bacterial Genome, Hoboken, NJ, USA, John Wiley and Sons, 2020, pp175 - 210, [Dorman, CJ], Notes: [Published online 14 February 2020], Book Chapter, PUBLISHED  DOI  URL
  

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Pozdeev G, Beckett MC, Mogre A, Thomson NR, Dorman CJ, The consequences of reciprocally exchanging the genomic sites of Integration Host Factor (IHF) subunit production for subunit stoichiometry and bacterial physiology in Salmonella enterica serovar Typhimurium, BioRxiv, 2021, Journal Article, PUBLISHED
Higgins CF, Dougan G, Roberts IS, Dorman CJ, 'Celebrating the Legacy of Fleming Prize Winners', Microbiology Society, 2020, -, Film production, PUBLISHED
Mogre, A., Dorman, C.J., The necessity to contain pathogenicity island expression constrained evolution of the housekeeping sigma factor RpoD and the global repressor of gene expression H-NS in Salmonella, DAPI 2020, Trinity College Dublin, 17 January, 2020, Invited Talk, PRESENTED
Dorman, CJ, Faculty of 1000 evaluation for Structural basis for osmotic regulation of the DNA binding properties of H-NS proteins,, F1000Prime- Post-publication peer review of the biomedical literature, 2020, Journal Article, PUBLISHED
Bogue MM, A Mogre, MC Beckett, NR Thomson, CJ Dorman, Network rewiring: physiological consequences of reciprocally exchanging the physical locations and growth-phase-dependent expression patterns of the Salmonella fis and dps genes, BioRxiv, 2020, Notes: [Preprint uploaded 8 July 2020], Journal Article, PUBLISHED
Dorman CJ, Faculty Opinions , Refining the H-NS protein family: a diversity of specialized core and accessory forms exhibit hierarchical transcriptional network integration. Post-publication peer review of the biomedical literature, 2020, Faculty Opinions, 2020, Journal Article, PUBLISHED
Dorman CJ, Faculty Opinion, post-publication review of the biomedical literature: "The hns gene of Escherichia coli Is transcriptionally down-regulated by (p)ppGpp.", Faculty Opinion, 2020, Journal Article, PUBLISHED
Pozdeev G, Mogre A, Dorman CJ, Consequences of producing DNA gyrase from a synthetic gyrBA operon in Salmonella enterica serovar Typhimurium, BioRxiv, 2020, Notes: [Published online 8.12.2020], Journal Article, PUBLISHED
Mogre A, Dorman CJ, Factors governing orthologous RpoD and H-NS evolution in Salmonella enterica Serovar Typhimurium and Escherichia coli, Access Microbiology, 2, (1), 2020, pp14 - 14, Notes: [Published online 1.1.2020], Meeting Abstract, PUBLISHED
Dorman CJ, Keynote talk: Fundamental principles in the regulation of bacterial gene expression, Biological Transactions: From Molecules to Organisms (BTMO-2019), Indian Institute of Science, Bangalore, India, 19 January, 2019, Usha Vijayraghavan, Umesh Varshney, Amit Singh, Invited Talk, PRESENTED

  

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Award Date
Trustee and member of the Governing Council of the Microbiology Society, Charles Darwin House, London, UK 2015-2020
Representative of the American Society for Microbiology at the European Congress of Microbiology, Leipzig, Germany 2013
Top performing editorial board member, Journal of Bacteriology American Society for Microbiology, Washington DC, USA 2013
Outstanding Service Award, American Society for Microbiology International Ambassador Programme 2012
Outstanding Service Award, American Society for Microbiology International Board 2011
Appointed Ambassador to Europe of the American Society for Microbiology, Washington DC, USA 2010-2013
Elected Fellow of the American Academy of Microbiology 2010
Elected Fellow of the Royal Society of Biology (FRSB) 2009
Elected Member of the European Academy of Microbiology 2009
Chartered Biologist (C.Biol.) status conferred by the Institute of Biology (UK) 2009
Elected Member of the Royal Irish Academy (MRIA) 2005
E.S. and R. Duthie Lecturer, TCD 2003
Lecture to Royal Swedish Academy of Sciences (hosted by the Nobel Prize Committee for Chemistry) 2002
Fellow of Trinity College Dublin (FTCD) 1997
Royal Irish Academy representative at Scientia Europaea, French Academy of Science 1997
MA (juri officii) Trinity College, Dublin 1995
Fleming Lecture, 50th Anniversary Meeting of the Society for General Microbiology, University of Bath, UK 1995
Fleming Prize of the Society for General Microbiology. 1994
Royal Society Fellowship Renewal 1992
Royal Society University Research Fellowship, Biochemistry Department, Medical Sciences Institute, Dundee University, UK 1988-1994
Elected to a Personal Research Fellowship of the Royal Society of Edinburgh. 1988 (declined)
Searle/Monsanto Postdoctoral Fellow, Department of Biochemistry, Medical Sciences Institute, University of Dundee 1984-1988
EMBO Fellowship (Biochemistry Department, Leicester University, UK) 1983-1984
Trinity Trust Postgraduate Award 1981-1984
College Prize (First place, degree exams; National University of Ireland) 1981
University Scholarship (First place, annual exams; UCD) 1980
University Scholarship (First place, annual exams; UCD) 1979
1. Gene regulatory mechanisms in Gram-negative bacteria of medical importance, with an emphasis on the roles of nucleoid-associated proteins and DNA topology in controlling transcription and site-specific recombination. 2. Horizontal transfer of gene regulatory elements and the evolution of gene control networks. 3. The dissection and interpretation of complex gene regulatory circuits using genomics methods. 4. Modulation of gene expression patterns in pathogenic bacteria during infection and intracellular growth.