| Staff Details | ||||
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| Personal Information | ||
| Name | Dorman, Charles James | |
| Main Department | Microbiology | |
| College Title | Professor | |
| cjdorman@tcd.ie | ||
| College Tel | +353 1 896 2013/2521 | |
| Web | http://people.tcd.ie/cjdorman | |
| Fax | 00353 1 679 9294 | |
| Biography | |
| Charles J Dorman holds the Chair of Microbiology at Trinity College Dublin and was head of the School of Genetics and Microbiology from 2008 to 2011. He is a Founding Member of the European Academy of Microbiology, a Fellow of the American Academy of Microbiology, a Member of the Royal Irish Academy, a Fellow of the Society of Biology and a Chartered Biologist. He is the European Ambassador of the American Society of Microbiology and was the Editor-in-Chief of "Microbiology" from 2005 to 2010, when he also served on the governing Council of the Society for General Microbiology (SGM). He was elected Treasurer of the SGM in 2011. A recipient of the SGM Fleming Medal and a former Royal Society Research Fellow and Lecturer in Biochemistry at Dundee University, his research focuses on the global regulation of gene expression in bacteria of medical importance, with an emphasis on the regulatory roles of DNA topology and nucleoid-associated proteins. | |
| Representations |
| Details | Date |
| Chair of Microbiology, Trinity College Dublin | Current |
| Head of the School of Genetics and Microbiology. Trinity College Dublin | 2008-2011 |
| Treasurer-elect, Society for General Microbiology | Current |
| Member, International Membership Committee, American Society for Microbiology | 2012-2015 |
| European Ambassador of the American Society for Microbiology | 2010-2012 |
| Membership of Professional Institutions, Associations, Societies |
| Details | Date From | Date To |
| European Academy of Microbiology (Founding Member) | Current | |
| American Academy of Microbiology (Fellow) | Current | |
| Royal Irish Academy (Member) | Current | |
| Society of Biology (Fellow) | Current | |
| Institute of Biology (Chartered Biologist) | Current | |
| More Memberships>>> | ||
| Awards and Honours | |
| Award | Date |
| Elected Treasurer of the Society for General Microbiology | 2011 |
| Ambassador to Europe, American Society for Microbiology | 2010-2012 |
| Outstanding Service Award, American Society for Microbiology International Board | 2011 |
| Elected Fellow of the American Academy of Microbiology | 2010 |
| Elected Fellow of the Society of Biology (FSB) | 2009 |
| More Awards and Honours>>> | |
| Description of Research Interests |
| 1. Gene regulatory mechanisms in Gram-negative bacteria of medical importance, with an emphasis on the roles of nucleoid-associated proteins and DNA topology in controlling transcription and site-specific recombination. 2. Horizontal transfer of gene regulatory elements and the evolution of gene control networks. 3. The dissection and interpretation of complex gene regulatory circuits using genomics methods. 4. Modulation of gene expression patterns in pathogenic bacteria during infection and intracellular growth. |
| Research Interests | |||
| BACTERIA | BACTERIAL | BACTERIAL GENE | BACTERIUM |
| BINDING-PROTEINS | BINDING-SITE | BINDING-SITES | BIOCHEMICAL |
| BIOCHEMICAL APPROACH | BIOCHEMISTRY | BIOLOGY | CURVED DNA |
| DEOXYRIBONUCLEIC-ACID GYRASE | DNA | DNA ARRAY | DNA BENDING |
| DNA BINDING | DNA GYRASE | DNA INVERSION | DNA MICROARRAYS |
| DNA RECOGNITION DOMAINS | DNA SUPERCOILING | DNA SUPERHELICITY | DNA TOPOLOGY |
| DNA-BINDING | DNA-BINDING ACTIVITY | DNA-BINDING DOMAIN | DNA-BINDING DOMAINS |
| DNA-BINDING PROTEIN | DNA-BINDING PROTEINS | DNA-BINDING SUBUNIT | ENVIRONMENTAL REGULATION |
| ENVIRONMENTAL-REGULATION | ESCHERICHIA-COLI K-12 | FIMBRIAE | FIMBRIAL PHASE VARIATION |
| FIS PROTEIN | GENE REARRANGEMENTS | GENE REGULATION | GENE-EXPRESSION |
| GENES | GENETIC | GENETIC MANIPULATION | GENETIC STRUCTURE |
| GENETIC-ANALYSIS | GENETICS | GENOME | GENOME COMPACTION |
| GENOME EVOLUTION | GENOME EXPRESSION ANALYSIS | GENOMES | GENOMIC ORGANIZATION |
| GENOMICS | GLOBAL REGULATOR | GROWTH-PHASE CONTROL | GROWTH-PHASE REGULATION |
| H-NS | HISTONE-LIKE PROTEINS | HNS | INTEGRATION HOST FACTOR |
| MESSENGER-RNA | MICROARRAY | MICROARRAY DATA | MICROBIAL ACTIVITY |
| MICROBIOLOGY | MICROORGANISM | MICROORGANISMS | MOLECULAR-BIOLOGY |
| MOLECULAR-CLONING | MOLECULAR-GENETICS | MOLECULAR-STRUCTURE | SALMONELLA-TYPHIMURIUM |
| SHIGELLA-FLEXNERI | SITE-SPECIFIC RECOMBINASES | TRANSCRIPTIONAL ACTIVATION | TYPE-1 FIMBRIAE |
| Publications |
| Peer Reviewed |
| Organization of the Bacterial Nucleoid (Chapter 311) in, Lennarz W, MD Lane MD, Craig NL , Encyclopedia of Biological Chemistry (2nd Edition), Oxford, UK, Elsevier, 2012, [Dorman CJ] | |
| Kröger C, SC Dillon, ADS Cameron, K Papenfort, SK Sivasankaran, K Hokamp, Y Chao, A Sittka, M Hébrard, K Händler, A Colgan, P Leekitcharoenphon, GC Langridge, AJ Lohan, B Loftus, S Lucchini, A Thompson, DW Ussery, CM Sharma, CJ Dorman, N Thomson, J Vogel, JCD Hinton, Global transcriptional mapping, RNA polymerase distribution and the unique sRNA complement of the model pathogen Salmonella enterica serovar Typhimurium, Proceedings of the National Academy of Science USA , 2012 Notes: [Published online 25 April 2012] DOI |
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| H-NS, global regulator of gene expression and organizer of the bacterial nucleoid in, A. Filloux , Bacterial Regulatory Networks, Norwich, Horizon Press, 2012, pp167 - 189, [CJ Dorman] Url |
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| McFarland KA, Dorman CJ, Autoregulated expression of the gene coding for the leucine-responsive protein, Lrp, in Salmonella enterica serovar Typhimurium , Microbiology, 154, (7), 2008, p2008 - 2016 DOI |
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| Kelly A, C Conway, T O Croinin, SGJ Smith, CJ Dorman, DNA supercoiling and the Lrp protein determine the directionality of fim switch DNA inversion in Escherichia coli K-12, Journal of Bacteriology, 188, (15), 2006, p5356 - 5363 Notes: [Highlighted in 'Microbe' (formerly 'ASM News') published by the American Society for Microbiology] DOI |
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| More Publications>>> | |
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