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Trinity College Dublin

Personal Information
College Photo Name Foster, Timothy James
Main Department Microbiology
College Title Professor
E-mail tfoster@tcd.ie
College Tel +353 1 896 1345/2014
Web http://people.tcd.ie/tfoster
 
Representations
Details Date
Public Health Services Research Fellow, National Institutes of Health. Department of Biochemistry and Molecular Biology, Harvard University 1978-79
Consultant to SmithKline Beecham, UK 1990-1995
Consultant to PanTherix, Glasgow 2000-2002
Ad hoc consultancy to Zeneca, Intercell, American Cyanamid, Unilever, Pantherix
Ad hoc consultant to Environmental Protection Agency, Ireland. Live-attenuated cholera vaccine license
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Membership of Professional Institutions, Associations, Societies
Details Date From Date To
Editorial Board of 'Molecular Microbiology' 1990 - present
Member of Scientific Advisory Board of Inhibitex Inc, Alpharetta, Georgia, USA 1998-2006 present
Editorial Board of 'Microbial Drug Resistance' 2002 - present
Editorial Board of 'Microbiology' 1990 1995
Editorial Board of 'Journal of Bacteriology' 1983 1989
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Awards and Honours
Award Date
Public Health Service International Research Fellow, U.S. Department of Health and Human Services, National Institutes of Health. 1978-1979
Elected to Fellowship of Trinity College Dublin 1981
E.S. and R. Duthie Lecture, Trinity College Dublin 2003
 
Research Interests
Antibiotic resistance mechanisms Antibiotics BIOFILMS BOVINE MASTITIS
Biomedical Research Training CLONING VECTORS CLUMPING FACTOR COLLAGEN ADHESIN
ENDOTHELIAL-CELLS EPIDERMOLYTIC TOXIN FIBRINOGEN FIBRONECTIN
FIBRONECTIN-BINDING PROTEINS FOREIGN-BODY INFECTION GRAM-POSITIVE BACTERIA HEMOLYSIN
Immune evasion mechanisms Infectious Diseases/Agents LEUKOCYTES Microbiology
Molecular Cloning Proteins and Macromolecules Recombinant DNA STAPHYLOCOCCUS-AUREUS
TOXIC SHOCK SYNDROME TOXIN Vaccine Vaccine development, delivery & adjuvants Vaccinology
virulence factors
 
Publications and Other Research Outputs
Peer Reviewed
Geoghegan JA, Monk IR, O'Gara JP, Foster TJ, Subdomains N2N3 of Fibronectin Binding Protein A Mediate Staphylococcus aureus Biofilm Formation and Adherence to Fibrinogen Using Distinct Mechanisms., Journal of bacteriology, 195, (11), 2013, p2675-83
DOI
Zapotoczna M, Heilbronner S, Speziale P, Foster TJ., Iron-Regulated SurfaceDeterminant (Isd) Proteins of Staphylococcus lugdunensis, Journal of Bacteriology, 194, (23), 2012, p6453 - 6467
Notes: [ PubMed ID: 23002220]
TARA - Full Text  DOI
Hair, PS, Echague, CG, Sholl, AM, Watkins, JA, Geoghegan, JA, Foster, TJ, Cunnion, KM, Clumping factor A interaction with complement factor I increases C3b cleavage on the bacterial surface of Staphylococcus aureus, and decreases complement-mediated phagocytosis, Infection and Immunity, 78, (4), 2010, p1717 - 1727
Notes: [PMID: 20100856 ]
TARA - Full Text
Foster, TJ, Colonization and infection of the human host by staphylococci: adhesion, survival and immune evasion., Veterinary Dermatology, 20, (5-6), 2009, p456 - 470
DOI
Fitzgerald, J.R., Loughman, A., Keane, F., Brennan, M., Knobel, M., Higgins, J., Visai, L., Speziale, P., Cox, D. and Foster, T.J. , Fibronectin-binding proteins of Staphylococcus aureus mediate activation of human platelets via fibrinogen and fibronectin bridges to integrin GPIIb/IIIa and IgG binding to the FCgammaRIIa receptor., Molecular Microbiology, 59, (1), 2006, p212 - 230
Notes: [PMID: 16359330]
DOI
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Last Updated:27-AUG-2014