| Staff Details | ||||
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| Personal Information | ||
| Name | Mc Manus, Ross | |
| Main Department | Clinical Medicine | |
| College Title | Professor in Molecular Medicine | |
| rmcmanus@tcd.ie | ||
| College Tel | +353 1 896 2139 | |
| Web | http://people.tcd.ie/rmcmanus | |
| Representations |
| Details | Date |
| Member of Molecular Medicine Ireland (MMI) Education Committee | 2003 - present |
| Council member, Irish Society of Human Genetics | 2004 - 2008 |
| Member, Scientific Committee, FINBAR, all-Ireland genetic epidemiology study of oesophageal cancer | 2003-present |
| Member, PHG Funded PI's and Researchers, All Researchers funded under Cycle 3 PRTLI - Programme for Human Genomics | |
| Member of LIPGENE WP1.1. Genetic association study of candidate genes in the Metabolic Syndrome in a large French cohort. | 2004 - 2009 |
| Membership of Professional Institutions, Associations, Societies |
| Details | Date From | Date To |
| American Society of Human Genetics | 2003 | present |
| Irish Society of Human Genetics | 2001 | present |
| European Society of Human Genetics | 2005 | present |
| Irish Society of Immunology | 2008 | present |
| Awards and Honours | |
| Award | Date |
| Wellcome Trust / Health Research Board 'New Blood' Fellowship | 1998 |
| Science Foundation Ireland Principal Investigator | 2010 |
| Description of Research Interests |
| I am interested in the genetics/genomics of common diseases with an inflammatory component, particularly coeliac disease, inflammatory bowel disease and sepsis. We currently also have programmes into the genetic basis of psoriasis and oesophageal cancers in conjunction with collaborators nationwide and in Europe. |
| Research Interests | |||
| Autoimmunity | Chronic inflamation | Coeliac disease | GENE EXPRESSION ANALYSIS |
| GENE POLYMORPHISM | GENETICS | Genetic Analysis of Systemic Inflammatory Response Syndrome (SARS) | Genetic Mapping, Gene Sequence |
| Genetics | Genetics of inflammatory disease | Genomes, Genomics | Genomic structure and function, molecular approaches to gene function |
| INFLAMMATORY BOWEL DISEASE | Inflammatory bowel disease | Molecular Genetics | PSORIASIS |
| SEPSIS |
| Publications and Other Research Outputs |
| Peer Reviewed |
| Apel M, Uebe S, Bowes J, Giardina E, Korendowych E, Juneblad K, Pasutto F, Ekici AB, McManus R, Ho P, Bruce IN, Ryan AW, Behrens F, Böhm B, Traupe H, Lohmann J, Gieger C, Wichmann HE, Padyukov L, Fitzgerald O, Alenius GM, McHugh NJ, Novelli G, Burkhardt H, Barton A, Reis A, Hüffmeier U., Variants in RUNX3 contribute to susceptibility to psoriatic arthritis exhibiting further common ground with ankylosing spondylitis, Arthritis & Rheumatism, 2013, p00-00 DOI |
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| Dubois PCA, Trynka G, Franke L, Hunt KA, Romanos J, Curtotti A, Zhernakova A, Heap GA, Ádány R, Aromaa A, Bardella MT, van den Berg LH, Bockett NA, de la Concha EG, Dema B, Fehrmann RS, Fernández-Arquero M, Fiatal S, Grandone E, Green PM, Groen HJ, Gwilliam R, Houwen RH, Hunt SE, Kaukinen K, Kelleher D, Korponay-Szabo I, Kurppa K, MacMathuna P, Mäki M, Mazzilli MC, McCann OT, Mearin ML, Mein CA, Mirza MM, Mistry V, Mora B, Morley KI, Mulder CJ, Murray JA, Núñez C, Oosterom E, Ophoff RA, Polanco I, Peltonen L, Platteel M, Rybak A, Salomaa V, Schweizer JJ, Sperandeo MP, Tack GJ, Turner G, Veldink JH, Verbeek , Weersma RK, Wolters VM, Urcelay E, Cukrowska B, Greco L, Neuhausen SL, McManus R, Barisani D, Deloukas P, Barrett JC, Saavalainen P, Wijmenga C, van Heel DA, Multiple common variants for celiac disease influencing immune gene expression, Nature Genetics, 42, (4), 2010, p295 - 302 Url TARA - Full Text DOI |
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| Romanos J, van Diemen CC, Nolte IM, Trynka G, Zhernakova A, Fu J, Bardella MT, Barisani D, McManus R, van Heel DA, Wijmenga C., Analysis of HLA and non-HLA alleles can identify individuals at high risk for celiac disease, Gastroenterology , 137, (133), 2009, p834-840 Notes: [PMID: 19454285 ] DOI |
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| Feighery CF, McManus R., Symposium on 'The challenge of translating nutrition research into public health nutrition'. Session 3: Joint Nutrition Society and Irish Nutrition and Dietetic Institute Symposium on 'Nutrition and autoimmune disease'. Recent advances in genetic understanding of coeliac disease. , Proceedings of the Nutrition Society, 68, (2), 2009, p122-126 Notes: [PubMed ID: 19243665 ] Url TARA - Full Text DOI |
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| More Publications and Other Research Outputs >>> | |
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