Dr. Frances O'Brien

Summary

European Commission (2021) Purpose: VALIDATION OF ARTIFICIAL MODELS FOR PREDICTING DECOMPENSATIONS AND IMPROVING QUALITY OF LIFE IN HEART FAILURE Topic HORIZON-HLTH-2021-DISEASE-04-04- Clinical validation of AI solutions for treatment and care. VALHALLA's (acronym for the group of contributors) main objective is to refine a proof-of-concept (AI) model previously devised in another patient cohort for prediction of decompensation in Heart Failure (HF) patients in telemonitoring scenarios. The study aims to optimise data capture methods (including evaluation of novel wearable devices for HF telemonitoring) which will be evaluated at different sites and countries. The study will use large-scale clinical validation of the model for HF management, comparing the standard of telecare with the AI-enabled predictive approach in terms of relevant clinical outcomes, to provide clinical evidence for its widespread adoption; to evaluate in terms of healthcare integration, acceptance and cost-effectiveness the feasibility of its incorporation in different settings across different European countries and Colombia; and to prepare for qualification according to regulatory requirements such as the new EU Medical Device Regulation. The outcomes The primary outcome will be the percentage of days lost due to unplanned cardiovascular hospital admissions or death from any cause, comparing remote patient management plus usual care to usual care alone during the individual patient follow-up time. The main secondary outcomes will be all-cause mortality and cardiovascular mortality during the individual patient's follow-up time plus 28 days after the last study visit, to a maximum of 197 days; percentage of days lost due to unplanned cardiovascular hospital admissions, and percentage of days lost due to unplanned heart failure hospital admissions; change in Minnesota Living with Heart Failure Questionnaire (MLHFQ) global score. The PROMs and PREMs, and QoL questionaries will also be measure.

Funding Agency

Horizon Health - European Commission

Programme

HORIZON-HLTH-2021-DISEASE-04-04

Project Type

Clinical Trial

Person Months

48

Summary

The primary objective of the study is to test the effectiveness of a study-specific blood pressure (B/P) monitor, and a study-specific weighing scales, together with the fluid heart tracker app (triple pack) in patients with heart failure. The secondary objective is to qualitatively assess participants and healthcare providers" perceived usefulness and clinical acceptability of the triple pack.

Funding Agency

Novartis pharmaceuticals

Programme

Clinical Trial

Project Type

Research

Person Months

6

Summary

The current global COVID-19 pandemic has radically transformed the provision of emergency healthcare in Ireland and represents the greatest medical challenge in decades. With respect to cardiovascular diseases, COVID-19 infection is associated with increased morbidity and mortality in patients with pre-existing cardiovascular disease especially hypertension and coronary heart disease. The fact that patients with cardiovascular disease frequently have underlying medical co-morbidities such as diabetes mellitus, hypertension and obesity, places them at a substantially increased risk for serious complications of COVID-19. This quantitative study will use explore baseline and follow-up data on patients admitted to the research site with COVID-19 between March 2020 and 2021 to determine if there are differences in clinical presentation of COVID-19 and outcomes of COVID-19 over time, between patients with pre-existing cardiovascular disease and risk factors and those with no such history.

Project Type

Quantitative

Person Months

20

Summary

Background: The term holistic care in nursing encompasses complete and comprehensive care requirements of the individual. This includes physical and mental health requirements. To achieve the delivery of mental health care in the acute care setting, nurses need to be adequately skilled to carry out mental health assessments and subsequently deliver appropriate interventions or identify the need for specialist referrals, as appropriate. A study conducted among oncology nurses in Ireland (Nash 2017) demonstrated that a range of mental health problems are encountered in practice. While nurses were equipped to handle some aspects of mental health care requirements, they generally felt that they were in need of additional information particularly in relation to complex conditions that extended beyond anxiety and depression. This question has not been raised among general nurses in the acute setting and therefore a decision was made to assess Registered General Nurses' needs in relation to supporting individuals with mental health problems in the acute care setting. In the United Kingdom, the National Service Framework for Mental Health (Department of Health 2000) recommended standards for planning and delivering mental health services in the UK. This is seen as an important issue for consideration in the Irish population also. Research question: What are the needs of Registered General Nurses in relation to supporting individuals with mental health problems in the acute setting? Study aim: To assess Registered General Nurses' needs in relation to supporting individuals with mental health problems in the acute care setting. Objectives: . To determine whether Registered General Nurses' feel adequately equipped to support individuals with mental health problems in the acute care setting. . If deficits are identified, this study seeks to ascertain the nurses' specific education and training needs that would help in supporting individuals with mental health problems in the acute care setting. . Based on the information collected, a needs analysis will be compiled and from this, a business and education plan will be proposed within the School of Nursing and Midwifery.

Funding Agency

Nursing Midwifery Planning and Development Unit

Programme

Research Grants €15,093

Project Type

Survey

Person Months

12

Summary

This study is being supported by two academics from the SNM, TCD since December 6th 2018. The project includes the heart efficiency team in Tallaght University Hospital and the study was funded in 2019 under the Heart Failure Service Integrated Care Project (Tallaght University Hospital).

Programme

Heart Failure Service Integrated Care Project

Project Type

Clinical - TCPHI