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| Professor Lawler graduated from the Genetics Department, Trinity College Dublin (TCD) (1985). He is Associate Professor in Experimental Haematology/ Oncology, TCD, Chief Molecular Geneticist at St James’s Hospital, Honorary Associate Professor in Oncogenetics, Smurfit Institute of Genetics, TCD and Visiting Professor in Medical Genetics and Molecular Medicine, University of Chieti, Italy. He has an active research group working on the molecular basis of cancer, with emphasis on translating this knowledge to biomarker discovery and novel anti-cancer approaches. He has published over 100 articles in international peer review journals. He has been honoured with numerous awards including the Vander Molen Prize for Leukaemia Research, the Ely Lilly Prize, the Ulster Cancer Foundation Prize and he has received both the St Lukes Medal and the Graves Medal for research. He is currently President of the Irish Association for Cancer Research, an all Ireland association for cancer researchers. He is a member of the Ireland/Northern Ireland/ National Cancer Institute Cancer Consortium Scientific Advisory Group and has recently been appointed as Chair of the Scholar Exchange Group. He is a founder member and one of the coordinators of the MSc in Molecular Medicine, TCD. He is founder and Chairperson of the highly successful Cancer Conference which has now become an annual event on the calendar. Professor Lawler was recently Director of Post-graduate Teaching and Learning in the School of Medicine, Trinity College Dublin and has a significant commitment to scholar exchange. He also is firmly committed to outreach and has participated in a number of community initiatives including “Your Health is your Wealth” and “Wise up! Its your life too!”. He is married to Ruth and they have two daughters, Sarah and Emily. |
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| Member, DMMC Cancer Principal Investigators, Trans-institutional grouping of Principal Investigators leading research on Cancer themes |
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| Member, Core Technology PI's, DMMC Principal Investigators leading the development of core technology platforms. |
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| Chairperson, Centre for Molecular Research in Cancer (Proposed), This consortium combines researchers with common interest in understanding cell cycle signaling and regulation with specific focus on two key cancer-related processes (cell cycle control, apoptosis) and/or three specific malignancy types (oesophageal, prostate and haematological). |
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| Chairperson, Prostate Cancer Research Consortium, Multi-centred consortium focused on the development of new diagnostic, prognostic and therapeutic agents for application in prostate cancer. |
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| Copy, Imaging Focus Group Meeting, 1-Day meeting on Biomedical Imaging - 8th June 2004 run in conjunction with TCINFrom single cell & molecular through to organ & whole body |
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| Apoptosis and cancer |
Cell cycle control and its manipulation in malignancy |
Cellular and molecular mechanisms regulating and resisting apoptosis |
Chimaeric status of long-term survivors of stem cell transplantation for severe aplastic anaemia. Study of quality of life and chimaerism in T cell lineages. An attempt to understand late graft rejection. |
| Chimeric status and outcome following stem cell transplantation for severe aplastic anaemia: the influence of GvHD prophylaxis. |
Chimerism and minimal residual disease in haematological malignancy |
Modes of assessment of fetal wellbeing |
Nonlinear Dynamics and Systems |
| Study of molecular response to Imatinib Mesylate in patients relapsing following stem cell transplantation for Chronic Myeloid Leukaemia. |
Study of the incidence of Autologous recovery following stem cell transplantation for severe aplastic anaemia in Europe in conjunction with the European Group for Blood and Bone Marrow transplantation. (EBMT). |
Transcriptional regulation |
D. S. O'Briain, O. Sheils, S. McElwaine, S. R. McCann and M. Lawler, Sorting out mix-ups. The provenance of tissue sections may be confirmed by PCR using microsatellite markers, American journal of clinical pathology, 106, (6), 1996, p758-64
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M. M. Humphries, D. Sheils, M. Lawler, G. J. Farrar, P. McWilliam, P. Kenna, D. G. Bradley, E. M. Sharp, E. F. Gaffney, M. Young and et al., Epidermolysis bullosa: evidence for linkage to genetic markers on chromosome 1 in a family with the autosomal dominant simplex form, Genomics, 7, (3), 1990, p377-81
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P. McWilliam, G. J. Farrar, P. Kenna, D. G. Bradley, M. M. Humphries, E. M. Sharp, D. J. McConnell, M. Lawler, D. Sheils, C. Ryan and et al., Autosomal dominant retinitis pigmentosa (ADRP): localization of an ADRP gene to the long arm of chromosome 3, Genomics, 5, (3), 1989, p619-22
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