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Dr. Mikel Egana

Associate Professor (Physiology)
BIOMEDICAL SCIENCES INSTITUTE
      
Profile Photo

Dr. Mikel Egana

Associate Professor (Physiology)
BIOMEDICAL SCIENCES INSTITUTE

 megana@tcd.ie

 3531896 1770


  AGE-RELATED IMPAIRMENT   CARDIOVASCULAR RISK-FACTORS   Clinical Trial   DIABETES-MELLITUS   Exercise physiology   EXERCISE TOLERANCE   Insulin   Musculoskeletal System   Obesity   POSTURE   Sports Medicine
Project Title
 The effect of the peripheral circulation and endothelial function on exercise tolerance in subjects with Type 2 Diabetes Mellitus.
From
2008
To
2011
Summary
Funding Agency
Science Foundation Ireland
Programme
Research Frontiers Programme (PI Dr Mikel Egaña)
Person Months
36
Project Title
 The effect of age and sex on the time course and mechanisms of adaptation in cardiovascular and metabolic health with exercise training in type 2 diabetes
From
2013
To
2016
Summary
Funding Agency
Health Research Board
Programme
Health Research Award (PI Dr Mikel Egaña)
Person Months
36
Project Title
 Cerebrovascular dynamic responses subsequent to highintensity interval vs moderate-intensity continuous training in men and women with type 2 diabetes.
From
2023
To
2027
Summary
Funding Agency
Science Foundation Ireland
Programme
Frontiers for the Future

Details Date From Date To
The Physiological Society
American College of Sports Medicine
European College of Sports Science
Buys P, Weston ME, Curtin EL, Gildea N and Egaña M, Cerebrovascular Reactivity to Hypocapnia Following Maximal Sprint Exercise Is Better Maintained in Females than Males, Physiologia, 6, (1), 2026, Journal Article, PUBLISHED  URL
O'Connor E, Kiely C, Gildea N, O'Shea D, Green S and Egaña M, Effects of pioglitazone with and without exercise training on cardiorespiratory fitness and oxygen uptake kinetics in type 2 diabetes., Diabetes, Obesity and Metabolism., 27(10), 2025, p5910-5920 , Journal Article, PUBLISHED  DOI
Weston M, Curtin E, Buys P, Gildea N and Egaña M., The acute effect of maximal sprint exercise on dynamic cerebral autoregulation in healthy young adults., Physiological Reports, 2025, pe70550-, Journal Article, PUBLISHED  DOI
Smyth E, O'Neill LM, Kearney N, Sheill G, Brennan L, Wade S, Grehan S, Begic S, Egaña M, Ryan R, Fitzmaurice GJ, Murphy RT, McKittrick M, Doyle SL, Walsh C, Ravi N, Donohoe CL, Reynolds JV, Hussey J, Guinan EM., Preoperative Exercise to Improve Fitness in Patients Undergoing Complex Surgery for Cancer of the Lung or Esophagus (PRE-HIIT): A Randomized Controlled Trial., Annals of surgery, 282, (5), 2025, p690-698 , Journal Article, PUBLISHED  DOI
McDermott A, Nevin A, Gildea N, Rocha J, O'Shea D, Egaña M., Muscle deoxygenation during ramp incremental cycle exercise in older adults with type 2 diabetes., European Journal of Applied Physiology, Feb, (124(2)), 2024, p561 - 571, Notes: [doi: 10.1007/s00421-023-05297-y], Journal Article, PUBLISHED  URL
Rocha J, Gildea N, O'Shea D, Green S & Egaña M , Priming exercise accelerates oxygen uptake kinetics during high-intensity cycle exercise in middle-aged individuals with type 2 diabetes, Frontiers in Physiology , 3, 2022, p1006993 , Journal Article, PUBLISHED  TARA - Full Text
Gildea N, McDermott A, Rocha J, Crognale D, Nevin A, O'Shea D, Green S & Egaña M , Low-volume HIIT and MICT speed VO2 kinetics during high-intensity "work-to-work" cycling with a similar time-course in type 2 diabetes., J Appl Physiol, (133), 2022, p273 - 287, Journal Article, PUBLISHED  TARA - Full Text
Green S, Kiely C, O'Connor E, Gildea N, O'Shea D, Egaña M., Differential effects of sex on adaptive responses of skeletal muscle vasodilation to exercise training in type 2 diabetes., Journal of diabetes and its complications, 36, (1), 2022, p108098 , Journal Article, PUBLISHED  DOI
Gildea N, McDermott A, Rocha J, O'Shea D, Green S and Egaña M. , Time course of changes in V̇o 2peak and O 2 extraction during ramp cycle exercise following HIIT versus moderate-intensity continuous training in type 2 diabetes, American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 320, (5), 2021, pR683 - R696, Journal Article, PUBLISHED  URL
Gildea N, McDermott A, Rocha J, O'Shea D, Green S and Egaña M. , Time-course of V̇o 2 kinetics responses during moderate-intensity exercise subsequent to HIIT versus moderate-intensity continuous training in type 2 diabetes, Journal of Applied Physiology, 130, (6), 2021, p1646 - 1659, Journal Article, PUBLISHED
  

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Award Date
Technicon Fellowship (Health Science Faculty, TCD) 2002-2004
My research fits within the discipline of exercise physiology and all my studies are carried out on humans. Currently, my main research is focused on the effect of different training interventions and pharmacological therapies on vascular and metabolic adaptations and exercise tolerance in type 2 diabetes, obesity and ageing. In addition, I am also interested on the effect of cold water immersion recovery interventions on subsequent exercise performance and on the postural effect (body tilt) on peripheral circulation, muscle activation and muscle endurance.