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Profile Photo

Professor Lidia Tajber

Professor (Pharmacy)
25/6/7 WESTLAND ROW
      
Profile Photo

Professor Lidia Tajber

Professor (Pharmacy)
25/6/7 WESTLAND ROW

 Lidia.Tajber@tcd.ie

 3531896 2787


Lidia Tajber is a Professor of Pharmaceutics and Pharmaceutical Technology in the School of Pharmacy and Pharmaceutical Sciences at Trinity College Dublin. She received her MPharm from the Medical University of Silesia, Poland, graduating with first-class honours and top of her class, and completed her PhD in Pharmaceutical Technology at Trinity in 2005. She joined the faculty as a lecturer in 2007 and was elected a Fellow of Trinity College Dublin in 2020. She also holds a postgraduate diploma in quality improvement and has completed the Research Leaders training programme. Professor Tajber has published more than 120 peer-reviewed papers in leading Pharmaceutical Sciences journals, accumulating over 5,000 citations and an h-index of 41. She has contributed to more than 100 international presentations and is frequently invited to deliver keynote and expert lectures. Her research impact is further reflected in several patent applications, including innovations related to porous microparticles and polymeric nanoparticles. Internationally recognised for her contributions to Pharmaceutical Sciences and Materials Science, Professor Tajber's work focuses on transforming drug substances into multicomponent systems designed to overcome poor solubility, a major global challenge affecting drug bioavailability and patient outcomes. Her laboratory is at the forefront of developing pharmaceutical ionic liquids and applying mechanochemistry as a sustainable, transformative strategy for materials design. Under her leadership, the research group integrates chemistry, physics, biology, and engineering to advance medicine quality and contribute to the United Nations Sustainable Development Goals. She has played key roles in collaborative, multidisciplinary, and industry-driven research consortia funded by Science Foundation Ireland, Enterprise Ireland, and the European Commission, including Irish Drug Delivery Network, Synthesis and Solid State Pharmaceuticals Centre, ORBIS, LongActNow, IMPACTIVE and eRaDicate. These initiatives have enabled high-impact research aimed at improving pharmaceutical product design and manufacturing for the benefit of public health. Professor Tajber teaches across undergraduate and postgraduate programmes at Trinity College Dublin, covering Pharmaceutics, Pharmaceutical Technology, Physical and Industrial Pharmacy, and Advanced Drug Delivery.
  Amorphous Materials   Computer modelling of pharmaceutical systems   Crystal engineering   DENDRIMERS   Drug Delivery Systems   Hydrogen bonding   LIQUID CRYSTALS   Nanotechnology   Pharmaceutical co-crystals   Pharmaceutical salts   Physical Chemistry   POLYMER   Polymers   POLYMORPHISM   Porous particles   Respiratory System   Spectroscopy   SPRAY DRYING   Thermal Analysis
Project Title
 Synthesis and Solid State Pharmaceutical Centre
From
2013
To
2019
Summary
Funding Agency
SFI
Programme
Reseach Centre
Project Title
 TRANS-INT
From
2012
To
Summary
Funding Agency
EU
Programme
7th European Framework Programme for Research and Technological Development
Project Title
 Solid State Pharmaceutical Cluster
From
2007
To
2013
Summary
Funding Agency
SFI
Programme
Strategic Research Cluster Programme
Project Title
 Active pharmaceutical ingredients as ionic liquids: significance of protonics and functional profiling for the design of effective medicines
From
2017
To
2021
Summary
A large proportion of pharmaceutical molecules exhibit low aqueous solubility and/or poor membrane transport properties resulting in low oral bioavailability and delivery problems. Thus, many compounds with high pharmacological activity are being dropped from development pipelines. To address the issue of poor solubility and/or permeability of active pharmaceutical ingredients, a new tactic is proposed whereby the active molecule is converted into an ionic liquid (IL), a functional material with superior physicochemical properties to the "parent" molecule. ILs comprise anions and cations and possess low lattice energy and low melting points, often well below 100 °C. Through the systematic investigations of structural properties of ILs, their methods of synthesis, the degree of ionisation and type of proton transport within the ILs as well as extensive pharmaceutical profiling including stability, solubility, permeability and in vitro toxicity, a new generation of ILs with tunable pharmaceutical properties (PILs) will be established. To demonstrate the pharmaceutical developability of PILs and their potential as a platform technology, prototype tablet formulations will be manufactured and tested using novel, bio-relevant dissolution stress test devices. A range of anti-inflammatory and anti-infective molecules will be examined due to their efficacy limitations that are often caused by low solubility and permeability.
Funding Agency
SFI
Programme
Career Development Award
Project Title
 Irish Drug Delivery Network
From
2007
To
2013
Summary
Funding Agency
SFI
Programme
Strategic Research Cluster Programme

Page 1 of 2
Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
Polish Fluent Fluent Fluent
Russian Basic Basic Medium
Details Date From Date To
International Association for Pharmaceutical Technology (APV) 2017 present
American Chemical Society 2013 present
Controlled Release Society 2008 present
American Association of Pharmaceutical Scientists 2007 present
Wdowiak K., Tajber L., Miklaszewski A., Cielecka-Piontek J., Application of the Box"Behnken Design in the Development of Amorphous PVP K30"Phosphatidylcholine Dispersions for the Co-Delivery of Curcumin and Hesperetin Prepared by Hot-Melt Extrusion, Pharmaceutics, 17, (1), 2025, Journal Article, PUBLISHED  DOI
Dudek M.K., Trzeciak K., Tajber L., Zajac J., Kazmierski S., Pindelska E., Makowski T., Svyntkivska M., Potrzebowski M.J., A New Look at the Mechanism of Cocrystal Formation and Coformers Exchange in Processes Forced by Mechanical and/or Thermal Stimuli " ex situ and in situ Studies of Low-Melting Eutectic Mixtures, Chemistry - A European Journal, 30, (11), 2024, pe202302138-, Journal Article, PUBLISHED  DOI
Kadri L, Carta M, Lampronti G, Delogu F, Tajber L., Mechanochemically Induced Solid-State Transformations of Levofloxacin., Molecular pharmaceutics, 21, (6), 2024, p2838-2853 , Journal Article, PUBLISHED  DOI
Kadri L, Casali L, Emmerling F, Tajber L., Mechanochemical comparison of ball milling processes for levofloxacin amorphous polymeric systems., International journal of pharmaceutics, 665, 2024, p124652 , Journal Article, PUBLISHED  DOI
Wdowiak K., Tajber L., Miklaszewski A., Cielecka-Piontek J., Sweeteners Show a Plasticizing Effect on PVP K30"A Solution for the Hot-Melt Extrusion of Fixed-Dose Amorphous Curcumin-Hesperetin Solid Dispersions, Pharmaceutics, 16, (5), 2024, Journal Article, PUBLISHED  DOI
Nandi S., Verstrepen L., Hugo Silva M., Padrela L., Tajber L., Collas A., Continuous Microfluidic Antisolvent Crystallization as a Bottom-Up Solution for the Development of Long-Acting Injectable Formulations, Pharmaceutics, 16, (3), 2024, Journal Article, PUBLISHED  DOI
Nandi S., Collas A., Tajber L., Padrela L., Supercritical enhanced atomization induced particle entrapment for continuous production of injectable micro and nano-suspensions, Journal of CO2 Utilization, 81, 2024, Journal Article, PUBLISHED  DOI
Mendez Canellas F., Geertman R., Tajber L., Padrela L., Sorbitol-coated indomethacin and naproxen particles produced by supercritical CO2-assisted spray drying, Journal of Supercritical Fluids, 199, 2023, p105969-, Journal Article, PUBLISHED  DOI
Nandi S., Padrela L., Tajber L., Collas A., Development of long-acting injectable suspensions by continuous antisolvent crystallization: An integrated bottom-up process, International Journal of Pharmaceutics, 648, 2023, p123550-, Journal Article, PUBLISHED  DOI
Garbiec E., Rosiak N., Zalewski P., Tajber L., Cielecka-Piontek J., Genistein Co-Amorphous Systems with Amino Acids: An Investigation into Enhanced Solubility and Biological Activity, Pharmaceutics, 15, (12), 2023, p2653-, Journal Article, PUBLISHED  DOI
  

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Tajber L, The curious case of ciprofloxacin: how to deal with "difficult" drugs molecules to improve their biopharmaceutical properties, Farmak's School of young scientists "Science and modern pharmaceutical manufacturing", Kiyv, Ukraine, 21 November, 2019, 2019, Invited Talk, PRESENTED
Umerska A, Tajber L, Polyelectrolyte complexes as nanoparticulate drug delivery systems, European Pharmaceutical Review, 20, (3), 2015, p36-40 , Notes: [Invited review], Journal Article, PUBLISHED

  


Award Date
Elected Fellow of Trinity College Dublin 2020
Researcher Highlight in 2018/19 Trinity College Dublin Provost & President's Annual Review 2019
Trinity College Postgraduate Award 2001
Distinction for the Masters thesis in the Master's Degree Dissertations Competition for Faculties of Pharmacy organised by Polish Pharmaceutical Society and Medical Universities 2001
First prize for the Masters thesis in the Interdepartmental Master's Degree Dissertations Competition 2000
Prize from the Czestochowa branch of the Polish Pharmaceutical Chamber for the grades achieved in university degree 2000
M.A. (jure officii) 2015