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Trinity College Dublin

Personal Information
College Photo Name Tipton, Keith
Main Department Biochemistry
College Title Fellow Emeritus
E-mail ktipton@tcd.ie
College Tel +353 1 896 1802
Web http://people.tcd.ie/ktipton
 
Representations
Details Date
Molecular Enzymology Group (Chairman), (Biochemical Society) 1995-1997
Neurochemical Group (Chairman) (Biochemical Society) 1998-1990
Publications Board, (Biochemical Society) 1982-89
Institute of Biology of Ireland (Chairman) 1985-87
Institute of Biology of Ireland (President) 1988-90
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Membership of Professional Institutions, Associations, Societies
Details Date From Date To
International Union of Biochemistry and Molecular Biology (IUBMB)
Irish Neurosciences Discussion Group
Hungarian Pharmacological Society (Honorary Member)
 
Awards and Honours
Award Date
M.R.I.A. Royal Irish Academy 1984
RIA Biochemistry Medal, Royal Irish Academy 1989
 
Description of Research Interests
Enzymology: regulation, kinetics, inhibition, isolation, applications. Enzyme bioinformatics: metabolic analysis and simulation. Systems biology. Neurochemistry: depression, degenerative diseases and 'neuroprotection'. Biochemical Pharmacology: drug design, ethanol.
 
Research Interests
Biochemistry Biochemistry, metabolism Bioinformatics Biosystematics
DEGENERATION Depression Design and synthesis of drugs Drug Metabolism
ENZYME INHIBITION ENZYME KINETICS ETHANOL Enzymology
NEUROPROTECTION Neurodegenerative Diseases/Disorders Neurophysiology
 
Publications
Peer Reviewed
Colivicchi, M.A., Raimondi, L., Bianchi, L., Tipton, K.F., Pirisino, R. and Della Corte, L., Taurine prevents streptozotocin impairment of hormone-stimulated glucose uptake in rat adipocytes. , EUROPEAN JOURNAL OF PHARMACOLOGY, 495, (2-3), 2004, p209 - 215
Seymour, C. B., Mothersill, C., Mooney, R., Moriarty, M. and Tipton, K. F., Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity, BRITISH JOURNAL OF CANCER, 89, (10), 2003, p1979 - 1986
O'Byrne, M. B. and Tipton, K. F., Taurine-induced attenuation of MPP+ neurotoxicity in vitro: a possible role for the GABA(A) subclass of GABA receptors, J. Neurochem, 74, 2000, p2087 - 2093
Kelly, J. A., Slator, G. R., Tipton, K. F., Williams, C. H. and Bauer, K., Kinetic Investigation of the Specificity of Porcine Brain Thyrotropin-releasing Hormone-degrading Ectoenzyme for Thyrotropin-releasing Hormone-like Peptides, J. Biol. Chem, 275, 2000, p16746 - 16751
Cunningham, C., Tipton, K. F. and Dixon, H. B. F. , Conversion of taurine into N-chlorotaurine (taurine chloramine) and sulphoacetaldehyde in response to oxidative stress, Biochem. J. , 330, 1998, p933 - 937
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Last Updated:24-MAY-2013