| Staff Details | ||||
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| Personal Information | ||
| Name | Tipton, Keith | |
| Main Department | Biochemistry | |
| College Title | Fellow Emeritus | |
| ktipton@tcd.ie | ||
| College Tel | +353 1 896 1802 | |
| Web | http://people.tcd.ie/ktipton | |
|   |
| Representations |
| Details | Date |
| Molecular Enzymology Group (Chairman), (Biochemical Society) | 1995-1997 |
| Neurochemical Group (Chairman) (Biochemical Society) | 1998-1990 |
| Publications Board, (Biochemical Society) | 1982-89 |
| Institute of Biology of Ireland (Chairman) | 1985-87 |
| Institute of Biology of Ireland (President) | 1988-90 |
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| Membership of Professional Institutions, Associations, Societies |
| Details | Date From | Date To |
| International Union of Biochemistry and Molecular Biology (IUBMB) | ||
| Irish Neurosciences Discussion Group | ||
| Hungarian Pharmacological Society (Honorary Member) |
|   | |
| Awards and Honours | |
| Award | Date |
| M.R.I.A. Royal Irish Academy | 1984 |
| RIA Biochemistry Medal, Royal Irish Academy | 1989 |
|   |
| Description of Research Interests |
| Enzymology: regulation, kinetics, inhibition, isolation, applications. Enzyme bioinformatics: metabolic analysis and simulation. Systems biology. Neurochemistry: depression, degenerative diseases and 'neuroprotection'. Biochemical Pharmacology: drug design, ethanol. |
| Research Interests | |||
| Biochemistry | Biochemistry, metabolism | Bioinformatics | Biosystematics |
| DEGENERATION | Depression | Design and synthesis of drugs | Drug Metabolism |
| ENZYME INHIBITION | ENZYME KINETICS | ETHANOL | Enzymology |
| NEUROPROTECTION | Neurodegenerative Diseases/Disorders | Neurophysiology |
|   |
| Publications |
| Peer Reviewed |
| Colivicchi, M.A., Raimondi, L., Bianchi, L., Tipton, K.F., Pirisino, R. and Della Corte, L., Taurine prevents streptozotocin impairment of hormone-stimulated glucose uptake in rat adipocytes. , EUROPEAN JOURNAL OF PHARMACOLOGY, 495, (2-3), 2004, p209 - 215 | |
| Seymour, C. B., Mothersill, C., Mooney, R., Moriarty, M. and Tipton, K. F., Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity, BRITISH JOURNAL OF CANCER, 89, (10), 2003, p1979 - 1986 | |
| O'Byrne, M. B. and Tipton, K. F., Taurine-induced attenuation of MPP+ neurotoxicity in vitro: a possible role for the GABA(A) subclass of GABA receptors, J. Neurochem, 74, 2000, p2087 - 2093 | |
| Kelly, J. A., Slator, G. R., Tipton, K. F., Williams, C. H. and Bauer, K., Kinetic Investigation of the Specificity of Porcine Brain Thyrotropin-releasing Hormone-degrading Ectoenzyme for Thyrotropin-releasing Hormone-like Peptides, J. Biol. Chem, 275, 2000, p16746 - 16751 | |
| Cunningham, C., Tipton, K. F. and Dixon, H. B. F. , Conversion of taurine into N-chlorotaurine (taurine chloramine) and sulphoacetaldehyde in response to oxidative stress, Biochem. J. , 330, 1998, p933 - 937 | |
| More Publications>>> | |
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