Skip to main content

Trinity College Dublin, The University of Dublin

Menu Search


Trinity College Dublin By using this website you consent to the use of cookies in accordance with the Trinity cookie policy. For more information on cookies see our cookie policy.

      
Profile Photo

Professor Alan Irvine

PROFESSOR OF DERMATOLOGY (Clinical Medicine)
PROFESSOR OF DERMATOLOGY (School Office - Medicine)
ST JAMESS HOSPITAL
      
Profile Photo

Professor Alan Irvine

PROFESSOR OF DERMATOLOGY (Clinical Medicine)
ST JAMESS HOSPITAL

 irvinea@tcd.ie

 3531 4162103

PROFESSOR OF DERMATOLOGY (School Office - Medicine)


I am a physician scientist and health system leader passionate about driving innovation to improve the lives of people living with atopic dermatitis, vascular anomalies, and rare genetic skin diseases. A Clarivate Highly Cited Researcher, I have co-authored more than 400 scientific publications and multiple US patents. My work spans disease mechanisms, translational medicine, and drug development, with a focus on turning scientific insight into meaningful patient impact. I have advised over 50 biotechnology and pharmaceutical companies across the full development pathway, from early discovery to late-stage trials and regulatory strategy, and regularly advise life science investors. My commitment to better patient outcomes extends beyond research through leadership roles as Founding Director of the Irish Skin Foundation and Founding Director (and current President) of the International Eczema Council. As President of the Irish Hospital Consultants Association, I served as lead negotiator representing almost 5,000 consultants in discussions with the Irish Government on the 2023 Public Consultant Contract.
  atopy   DERMATITIS   DERMATOLOGY   eczema   Genetic/Molecular epidemiology   Genomic structure and function, molecular approaches to gene function   Human genetics   Mammilian and human genetics and genomics   Molecular population genetics
Details Date
President, International Eczema Council 2024
President, Irish Hospital Consultants Association 2020
Grant Reviewer: The Wellcome Trust, Medical Research Council (UK), The Italian National Telethon, DEBRA International, British Skin Foundation Current
Reviewer: The Journal of Investigative Dermatology, The British Journal of Dermatology, Experimental Dermatology, European Journal of Human Genetics, Clinical and Experimental Dermatology, Journal of Allergy And Clinical Immunology, Allergy Current
Details Date From Date To
Association of Physicians of Great Britain & Ireland - Member 2008- Current
Royal College of Physicians of London - Fellow 2007- Current
The Royal College of Physicians of Ireland - Fellow 2004- Current
British Association of Dermatologists - Ordinary Member 2001- Current
Irish Association of Dermatologists - Member 1999- Current
Irish Society of Human Genetics - Member 1999- Current
British Society for Pediatric Dermatology - Member 1995 Current
Royal Academy of Medicine in Ireland - Member 1998- Current
European Society for Dermatological Research - Member 1998- Current
Society for Investigative Dermatology - Member 1996- Current
British Society for Investigative Dermatology - Member 1996- Current
The Dowling Club - Member 1994- Current
Irvine A.D., Paller A.S., Siegfried E.C., Cork M.J., Beck L.A., Eichenfield L.F., Swanson L., Hamon S.C., Horowitz J.E., Farrell A.B., Hatsell S., Zhang A., Bansal A., You X., Chen Z., Levy S., Cyr S.L., Dupilumab treatment improves linear growth and bone biomarkers in children with atopic dermatitis: Post hoc analysis of a phase 3 randomized, placebo-controlled clinical trial and an open-label extension study, Journal of the American Academy of Dermatology, 95, (5), 2026, p1324 - 1334, p1324-1334 , Journal Article, PUBLISHED  DOI
Silverberg J.I., Prajapati V.H., Abraham S., Irvine A.D., Gooderham M.J., Guttman-Yassky E., Tanizaki H., Rademaker M., Chen S.H., Moreira A., Ta R., Lee W.-J., Eyerich K., Achieving Minimal Disease Activity in Atopic Dermatitis Is Associated with Fewer Flares, Reduced Healthcare Resource Utilization, and Improved Disease Control: Analysis from the Real-World MEASURE-AD Study, Dermatology and Therapy, 16, (9), 2026, p4617 - 4630, p4617-4630 , Journal Article, PUBLISHED  DOI
Lv K., Forde K.M., Moon A.T., Zhang Z., Pang L., Nomakuchi T.T., Zhao S., Murrell J.R., Wood K.H., Irvine A.D., Gray C., Lin Z., Wang H., Loss-of-function variants in EPHX3 cause nonsyndromic epidermal differentiation disorders, British Journal of Dermatology, 195, (3), 2026, p473 - 482, p473-482 , Journal Article, PUBLISHED  DOI
Ruge I.F., Nielsen M.-L., Halling A.S., Gerner T., Rinnov M.R., Trautner S., Thomsen S.F., Skov L., Egeberg A., Jakasa I., Kezic S., Irvine A.D., Guttman-Yassky E., Bonnelykke K., Thyssen J.P., Preterm birth is associated with reduced risk of atopic dermatitis and a distinct allergic comorbidity profile in early childhood, British Journal of Dermatology, 195, (3), 2026, p496 - 505, p496-505 , Journal Article, PUBLISHED  DOI
Guttman-Yassky E., Irvine A.D., Gooderham M., Weidinger S., Spelman L., Silverberg J.I., Crane H., ElMaraghy H., DeLuca-Carter L., Piruzeli M.L.B., Martimianaki G., Pierce E., Agell H., Thaci D., Three-Year Efficacy and Safety of Lebrikizumab in Patients with Moderate-to-Severe Atopic Dermatitis: A Long-Term Extension (ADjoin), Dermatology and Therapy, 16, (8), 2026, p4021 - 4039, p4021-4039 , Journal Article, PUBLISHED  DOI
Silverberg J.I., Irvine A.D., Foley P., Del Rosso J., Puig L., Stein Gold L., Kamata M., Wollenberg A., Hong H.C.-H., Chu C.-Y., Binamer Y., Dossenbach M., Casillas M., Gallo G., Akmaz B., Rand K., Chovatiya R., A Durability Index for Atopic Dermatitis: Indirect Comparison of Lebrikizumab, Dupilumab, and Tralokinumab in Maintaining Efficacy Under Variable Treatment Adherence, Dermatology and Therapy, 16, (8), 2026, p4001 - 4020, p4001-4020 , Journal Article, PUBLISHED  DOI
Chivardi C., Gribaleva E., Coker B., Tsoi M.F., Carroll R., Prieto Merino D., Baden M., Beattie P.E., Brown S.J., Burton T., Hearn R., Ingram J.R., Irvine A.D., Johnston G.A., Man I., Ogg G., Wan M., Warren R.B., Woolf R.T., Reynolds N.J., Ardern-Jones M.R., Flohr C., Manca A., Ali M., Ardern-Jones M.R., Baldago J., Bale T., Beattie P.E., Brown S.J., Brown V., Cork M.J., Chua S.-L., Darne S., Fahy C., Ferguson L., Flohr C., Hearn R., Housam N., Ingram J.R., Johnston G.A., Ladoyanni E., Layton A., Leitch C., Simpson R., Man I., Moffit D., Newell L., Searle J., Paget S., Petrof G., Popli U., Rennie C., Reynolds N.J., Rouhani N., Sergeant A., Thompson B., Wahie S., Warren R.B., Weller R., Wernham A., Woolf R.T., Healthcare resource use, costs and health-related quality of life in the UK"Irish Atopic eczema Systemic Therapy Register (A-STAR): a pilot study, Skin Health and Disease, 6, (4), 2026, p459 - 467, p459-467 , Journal Article, PUBLISHED  DOI
Zhiyong Zheng, Manon Dechêne-Tempier, Telmo O. Paiva, Can Wang, Sophie Dunn, Julianne Clowry, Alan D. Irvine, Joan A. Geoghegan, Yves Dufrêne, Nanoscale Mechanics of FnBPB-Mediated Adhesion of Staphylococcus aureus to Skin Ligands, ACS Nano, 20, (8), 2026, p7279 - 7290, p7279-7290 , Journal Article, PUBLISHED  DOI
Amy S. Paller, Alan D. Irvine, Eulàlia Baselga, Marlies de Graaf, Elaine C. Siegfried, Michael J. Cork, Michele Ramien, Lawrence F. Eichenfield, Bryan Adams, Rajan Gupta, Marius Ardeleanu, Annie Zhang, Growth Assessment in Children Under 12 Years With Moderate"to"Severe Atopic Dermatitis Included in the PEDISTAD Observational Registry, Pediatric Dermatology, 2026, Journal Article, PUBLISHED  DOI
Cristina Grechin, Alan D. Irvine, Natasha Jordan, Niamh Leonard, Talulla Dunne, Bairbre Wynne, Pachydermoperiostosis: a mimicker of inflammatory arthritis, Clinical and Experimental Dermatology, 2026, Journal Article, PUBLISHED  DOI
  

Page 1 of 57

  


Award Date
Fellow, Royal Society of Biology, London, United Kingdom 2024
Fellow, Trinity College Dublin, Trinity College Dublin, Dublin, Ireland 2024
ESDR Plenary Lecture at EADV Annual Meeting, European Society for Dermatological Research, Geneva, Switzerland 2022
International Fellowship (IntFRSE), Royal Society of Edinburgh, Edinburgh, United Kingdom 2021
Parkes Weber Lecture, Royal College of Physicians of London, London, United Kingdom 2021
Hurwitz Lecture, Society For Pediatric Dermatology, Indianapolis, United States 2021
Membership, Academia Europaea, London, United Kingdom 2020
Honorary Membership, Société Française de Dermatologie et de Pathologie Sexuellement Transmissible, Paris, France 2019
Membership (MRIA), Royal Irish Academy, Dublin, Ireland 2019
Honig Honorary Lecture, Children's Hospital of Philadelphia, Philadelphia, United States 2018
Marion Sulzberger Memorial Lecture, American Academy of Dermatology, Schaumburg, United States 2018
RW Goltz International Lectureship, University of Minnesota, Minneapolis, United States 2016
Sydney Watson Smith Lecture/Medal, Royal College of Physicians of Edinburgh, Edinburgh, United Kingdom 2015
Jerry Dolovich Memorial Lectureship, American Academy of Allergy, Asthma and Immunology, Milwaukee, United States 2013
Paul Gerson Unna Award, Deutsche Dermatologische Gesellschaft, Berlin, Germany 2007
Prix de La Foundation La Roche-Posay 2006
Research Project of the Year, Times Higher Education Supplement, London, United Kingdom 2006
Geoffrey Dowling Fellowship, British Association of Dermatologists 2000
Fulbright Scholar, Fulbright Association, Washington, United States 2000
Canadian Dermatology Association (CDA) Trophy, British Association of Dermatologists, London, United Kingdom 2000
Young Investigator Fellowship, British Society for Investigative Dermatology 1999
Disease mechanisms and therapeutic development in inflammatory skin diseases, vascular anomalies and rare genetic skin disease