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Dr. Anne Molloy

Fellow Emeritus (Clinical Medicine)

 amolloy@tcd.ie

 

Fellow Emeritus (Biochemistry)


Research Tags

  Age related diseases   Folate, Vitamin B12   Metabolism and metabolic diseases   Molecular nutrition   Population based intervention trials

Representations

Details Date
Folic acid Review Group, organized by Food Safety authority of Ireland, Ireland September 2014-ongoing
Expert Advisor WHO guideline development meeting on 'Optimal blood folate concentrations in women of reproductive age for prevention on Folate and Vitamin B12 deficiencies' September 2013
Research Ethics Committee, Coombe womens' Hospital 2002-2012
Editorial Board, British Journal of Nutrition 2004-2009
Expert Advisor at the Biomarkers of Nutrition for Development (BOND) Vitamin B12 Consultation, Office of Dietary Supplements, NIH, Washington, September 2012
Expert Advisor at the Biomarkers of Nutrition for Development (BOND) Vitamin B12 Consultation, Office of Dietary Supplements, NIH, Washington, December 2012
Expert Panel for the project "Identifying Research Needs for Assessing Safe Use of High Intakes of Folic Acid" organized by the Office of Health Assessment and Translation, (NIEHS and ODS, National Institutes of Health, USA) 2014-2015
WHO Technical Consultant on Folate and Vitamin B12 Deficiencies October 2005
Expert advisor at the NHANES Folate and Vitamin B12 Assessment Round-Table meeting hosted by the Office of Dietary Supplements, NIH, Washington, 15th -16th July 2010
Meeting Chair and Expert advisor at the World health Organization/Centers for Disease Control (WHO/CDC) Technical Consultation on "Optimal blood folate concentrations in women of reproductive age for prevention of neural tube defects" Atlanta, Georgia, USA . August 2012
Member of the planning committee (coordinator Professor Lindsay Allen, University of California, Davis) for Track 2 of the Micronutrient Forum Conference, held in Addis Ababa, Ethiopia, June 2014 2013-2014

Memberships

Membership of Professional Institutions, Associations, Societies

Details Date From Date To
The Biochemical Society 1976 2008
The Nutrition Society 2005 date
American society of Nutrition 2011 date
Deirdre M. A. O"Connor, Siobhan Scarlett, Céline De Looze, Aisling M. O"Halloran, Eamon Laird, Anne M. Molloy, Robert Clarke , Christine A. McGarrigle and Rose Anne Kenny, Low folate predicts accelerated cognitive decline: 8-year follow-up of 3140 older adults in Ireland, European Journal of Clinical Nutrition, 76, 2022, p950-957 , Notes: [doi:https://doi.org/10.1038/s41430-021-01057-3], Journal Article, PUBLISHED  TARA - Full Text  DOI
Eamon Laird and Aisling M. O'Halloran and Anne M Molloy and Martin Healy and Belinda Hernandez and Deirdre O'Connor and Rose Anne Kenny and Robert Briggs, Low vitamin B 12 but not folate is associated with incident depressive symptoms in community-dwelling older adults: a 4-year longitudinal study, British Journal of Nutrition, 2021, p1--22 , Journal Article, PUBLISHED  TARA - Full Text  DOI
O'Connor DMA, Laird EJ, Carey D, O'Halloran AM, Clarke R, Kenny RA, Molloy AM., Plasma concentrations of vitamin B12 and folate and global cognitive function in an older population: Cross-sectional findings from The Irish Longitudinal Study on Ageing (TILDA)., The British journal of nutrition, 2020, p1-25 , Journal Article, PUBLISHED  DOI
Deirdre M A O'Connor, Eamon J Laird, Daniel Carey, Aisling M O'Halloran, Robert Clarke, R A Kenny, Anne M Molloy, Plasma concentrations of vitamin B12 and folate and global cognitive function in an older population: cross-sectional findings from The Irish Longitudinal Study on Ageing (TILDA), British Journal of Nutrition, 124, 2020, p602-610 , Notes: [doi: doi:10.1017/S0007114520001427], Journal Article, PUBLISHED  TARA - Full Text  DOI
Cawley S, O'Malley EG, Kennedy RAK, Reynolds CME, Molloy AM, Turner MJ., The relationship between maternal plasma homocysteine in early pregnancy and birth weight., J Matern Fetal Neonatal Med, 2019, p1-5 , Journal Article, PUBLISHED  DOI
Moore K, Hughes CF, Hoey L, Ward M, Cunningham C, Molloy AM, Strain JJ, McCarroll K, Casey MC, Tracey F, Laird E, O'Kane M, McNulty H., B-vitamins in Relation to Depression in Older Adults Over 60 Years of Age: The Trinity Ulster Department of Agriculture (TUDA) Cohort Study., Journal of the American Medical Directors Association, 2019, p551-557.e1 , Journal Article, PUBLISHED  DOI
McNulty H, Rollins M, Cassidy T, Caffrey A, Marshall B, Dornan J, McLaughlin M, McNulty BA, Ward M, Strain JJ, Molloy AM, Lees-Murdock DJ, Walsh CP, Pentieva K., Effect of continued folic acid supplementation beyond the first trimester of pregnancy on cognitive performance in the child: a follow-up study from a randomized controlled trial (FASSTT Offspring Trial)., BMC medicine, 17, (1), 2019, p196 , Journal Article, PUBLISHED  DOI
Stevelink R, Pangilinan F, Jansen FE, Braun KPJ, International League Against Epilepsy Consortium on Complex Epilepsies, Molloy AM, Brody LC, Koeleman BPC., Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy., Molecular genetics and metabolism reports, 21, 2019, p100518 , Journal Article, PUBLISHED  DOI
O'Halloran AM, Laird EJ, Feeney J, Healy M, Moran R, Beatty S, Nolan FM, Molloy AM, Kenny RA. , Circulating micronutrient biomarkers are associated with three measures of frailty: Evidence from The Irish Longitudinal Study on Ageing (TILDA). , JAMDA, 2019, Journal Article, IN_PRESS  TARA - Full Text  DOI
Laird EJ, McNicholas T, O'Halloran AM, Healy M, Molloy AM, Carey D, O'Connor D, McCarroll K, Kenny RA., Vitamin D Status Is Not Associated With Orthostatic Hypotension in Older Adults., Hypertension (Dallas, Tex. : 1979), 74, (3), 2019, p639-644 , Journal Article, PUBLISHED  TARA - Full Text  DOI
  

Page 1 of 22
Deirdre O'Connor , Anne M. Molloy , Eamon Laird, Rose Anne Kenny and Aisling M. O"Halloran, Sustaining an ageing population: the role of micronutrients in frailty and cognitive impairment, Proceedings of the Nutrition Society, Conference on `Food and nutrition: Pathways to a sustainable future" Symposium four: Sustaining an ageing population, (82), 2023, pp315-328 , Conference Paper, PUBLISHED
Molloy AM, Pentieva K, McNulty B, McNulty H., Reply to SW D'Souza et al, American Journal of Clinical Nutrition, 98, (6), 2013, p1598 - 1598, Journal Article, PUBLISHED
A.M. Molloy, J.M. Scott., Nutrition and metabolism., Current Opinions in Lipidology , 16, (4), 2005, p494-496 , Review, PUBLISHED

  

Awards and Honours

Award Date
Fellow, Trinity College Dublin 2015
Global Experts Network on Spina Bifida and Hydrocephalus 2014

Research Interests

Description Of Research Interests

. The role of folate and vitamin B12 in pregnancy: This incorporates two principal areas; (1) the cause of folate responsive neural tube defects, in particular the nutritional, biochemical and genetic parameters associated with these disorders and (2) the effects of inadequate folate or vitamin B12 nutrition on complications of pregnancy and adverse pregnancy outcomes. The role of these vitamins in other congenital disorders including oro-facial clefts and congenital heart disease is an extension of this area of interest. . The uptake and utilisation of folates in normal and deficient states: A particular area of interest is the effect of genetic variants in folate related enzymes on folate status and metabolism. Research methods include cell culture studies and studies on nutritional status in human subjects, stratified according to a genotype of interest. . The development and application of new techniques in the analysis of folates and folate related metabolites. including HPLC methods, amino acid analysis, radioisotope methods, microbiological assays and cell culture technology. . Links between folate and vitamin B12; specifically, the influence of folate and vitamin B12 status on methylation reactions and s-adenosylmethionine metabolism.