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Trinity College Dublin

Personal Information
College Photo Name Corvin, Aiden Peter
Main Department Psychiatry
College Title Professor Consultant
E-mail acorvin@tcd.ie
College Tel +353 1 896 2468
Web http://people.tcd.ie/acorvin
 
Biography
I completed my medical degree at University College Cork in 1993. Following additional medical training I joined the Dublin University Training Scheme in Psychiatry in 1995 and completed my Membership of the Royal College of Psychiatrists (UK) in 1998. As a research fellow working on the UK-Irish Bipolar Sibling Pair Study at TCD I developed an interest in genetics and was subsequently awarded a Wellcome Trust Training Fellowship in 1999 to investigate the genetics of schizophrenia and other psychotic disorders. This was the seed for the Psychosis Research Group at the Neuropsychiatric Genetics Laboratory, TCD. I completed Higher Specialist Training in Psychiatry in 2005, the year in which I completed my PhD in Molecular Genetics. I was appointed Senior Lecturer in Psychiatry at TCD and Consultant Psychiatrist at St James's Hospital, Dublin in 2006. My research focus is on developing a better understanding of the molecular aetiology of psychotic disorders (e.g. schizophrenia and bipolar disorder) and to translate this into improvements in clinical care. This work involves a highly motivated, talented and multidisciplinary team of researchers. Our group have published more than 50 peer-reviewed research articles in journals including Nature, Nature Genetics, Archives of General Psychiatry and Biological Psychiatry since 2001. We receive substantial research funding from many sources including the Wellcome Trust, Science Foundation Ireland, Health Research Board and NIH.
 
Description of Research Interests
I am interested in applying genomics methods to improving understanding of heritable major mental disorders and cognitive processes. Specifically, my research involves the identification and characterization of genes/molecular pathways contributing to disorders such as schizophrenia and bipolar disorder. I have headed the Psychosis Research Group at the Neuropsychiatric Genetics Laboratory since 1999. The group's research activities span from the genome to clinical symptoms (including genomics, biostatistics, bioinformatics, clinical phenotyping, neuropsychology, electrophysiology and neuroimaging). We collaborate with local researchers at the Institute of Molecular Medicine, Department of Genetics and TCIN. We are members of the International Schizophrenia Consortium and collaborate with researchers in the UK, Italy, Australia and US. I am also involved in projects relating to the genetics of cognition and synaesthesia.
 
Research Interests
Aetiology of mental illness Cognitive dysfunction in psychotic disorders Neurodegenerative diseases including schizophrenia & Alzheimer's disease Neurogenetics
Psychiatric genetics Schizophrenia
 
Publications and Other Research Outputs
Peer Reviewed
Donohoe G, Walters J, Hargreaves A, Rose EJ, Morris DW, Fahey C, Bellini S, Cummins E, Giegling I, Hartmann AM, Möller HJ, Muglia P, Owen MJ, Gill M, O'Donovan MC, Tropea D, Rujescu D, Corvin A, Neuropsychological Effects Of The CSMD1 Genome-Wide Associated Schizophrenia Risk Variant rs10503253., Genes, Brain, and Behavior, 12, (12), 2013, p203- 209
Notes: [PMID: 23320435]
DOI
Ruderfer DM, Chambert K, Moran J, Talkowski M, Chen ES, Gigek C, Gusella JF, Blackwood DH, Corvin A, Gurling HM, Hultman CM, Kirov G, Magnusson P, O'Donovan MC, Owen MJ, Pato C, St Clair D, Sullivan PF, Purcell SM, Sklar P, Ernst C, Mosaic copy number variation in schizophrenia., European journal of human genetics : EJHG, 2013
Notes: [pre-print]
DOI
Quinn EM, Cormican P, Kenny EM, Hill M, Anney R, Gill M, Corvin A, Morris DW. , Development of strategies for SNP detection in RNA-seq data: application to lymphoblastoid cell lines and evaluation using 1000 genomes data., PLos One, 2013
Hamshere M, Walters JT, Smith R, et al., Genome-wide significant associations in schizophrenia to ITHIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the schizophrenia PGC., Molecular Psychiatry, 18, (6), 2013, p708-712
DOI
More Publications and Other Research Outputs >>>
 

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Last Updated:24-APR-2014