| Staff Details | ||||
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| Personal Information | ||
| Name | Corvin, Aiden Peter | |
| Main Department | Psychiatry | |
| College Title | Associate Professor Consultant | |
| acorvin@tcd.ie | ||
| College Tel | +353 1 896 2468 | |
| Web | http://people.tcd.ie/acorvin | |
| Biography | |
| I completed my medical degree at University College Cork in 1993. Following additional medical training I joined the Dublin University Training Scheme in Psychiatry in 1995 and completed my Membership of the Royal College of Psychiatrists (UK) in 1998. As a research fellow working on the UK-Irish Bipolar Sibling Pair Study at TCD I developed an interest in genetics and was subsequently awarded a Wellcome Trust Training Fellowship in 1999 to investigate the genetics of schizophrenia and other psychotic disorders. This was the seed for the Psychosis Research Group at the Neuropsychiatric Genetics Laboratory, TCD. I completed Higher Specialist Training in Psychiatry in 2005, the year in which I completed my PhD in Molecular Genetics. I was appointed Senior Lecturer in Psychiatry at TCD and Consultant Psychiatrist at St James's Hospital, Dublin in 2006. My research focus is on developing a better understanding of the molecular aetiology of psychotic disorders (e.g. schizophrenia and bipolar disorder) and to translate this into improvements in clinical care. This work involves a highly motivated, talented and multidisciplinary team of researchers. Our group have published more than 50 peer-reviewed research articles in journals including Nature, Nature Genetics, Archives of General Psychiatry and Biological Psychiatry since 2001. We receive substantial research funding from many sources including the Wellcome Trust, Science Foundation Ireland, Health Research Board and NIH. | |
| Description of Research Interests |
| I am interested in applying genomics methods to improving understanding of heritable major mental disorders and cognitive processes. Specifically, my research involves the identification and characterization of genes/molecular pathways contributing to disorders such as schizophrenia and bipolar disorder. I have headed the Psychosis Research Group at the Neuropsychiatric Genetics Laboratory since 1999. The group's research activities span from the genome to clinical symptoms (including genomics, biostatistics, bioinformatics, clinical phenotyping, neuropsychology, electrophysiology and neuroimaging). We collaborate with local researchers at the Institute of Molecular Medicine, Department of Genetics and TCIN. We are members of the International Schizophrenia Consortium and collaborate with researchers in the UK, Italy, Australia and US. I am also involved in projects relating to the genetics of cognition and synaesthesia. |
| Research Interests | |||
| Aetiology of mental illness | Cognitive dysfunction in psychotic disorders | Neurodegenerative diseases including schizophrenia & Alzheimer's disease | Neurogenetics |
| Psychiatric genetics | Schizophrenia |
| Publications |
| Peer Reviewed |
| Hill MJ, Kenny E, Roche S, Morris DW, Corvin A, Hawi Z, Gill M, Anney RJ., Allelic expression imbalance of the schizophrenia susceptibility gene CHI3L1: evidence of cis-acting variation and tissue specific variation. , Psychiatric Genetics, 21, (6), 2011, p281 - 286 Notes: [PMID: 21642896] DOI |
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| O'Donoghue T, Morris DW, Fahey C, Costa AD, Foxe JJ, Hoerold D, Tropea D, Gill M, Corvin A, Donohoe G, A NOS1 variant implicated in cognitive performance influences evoked neural responses during a hight density EEG study of early visual perception. , Human Brain Mapping, 2011 Notes: [PMID: 21520349] Url DOI |
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| Cummings E, Donohoe G, Morris DW, Gill M, Corvin A. , Clinical symptomatology and the psychosis risk gene, ZNF804A, Schizophrenia Research, 122, (1-3), 2010, p273-275 Url TARA - Full Text DOI |
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| International Schizophrenia Consortium, Common polygenic variation contributes to risk of schizophrenia and bipolar disorder., Nature, 460, (7256), 2009, p748-752 Notes: [PMID: 19571811] DOI |
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| International Schizophrenia Consortium, Greater burden of rare copy number variants in schizophrenia, Nature, 7210, (455), 2008, p237 - 241 Notes: [pmid: 18668038] Url DOI |
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| More Publications>>> | |
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