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Professor John Reynolds

Professor & Head of Department (Surgery)

  Anti-oxidants in inflammatory disease   Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus   Liver and gut immune function in patients undergoing complex major surgery   Molecular predictors of response and resistance to chemotherapy and radiation therapy   Transcription factors in inflammation and neoplasia of the oesophagus   Upper gastrointestinal physiology
Details Date
Member, DMMC Inflammation, Immunity & Infection Principal Investigators, DMMC Principal Investigators leading research in inflammation, immunit and infection.
Member, Centre for Molecular Research in Cancer (Proposed), This consortium combines researchers with common interest in understanding cell cycle signaling and regulation with specific focus on two key cancer-related processes (cell cycle control, apoptosis) and/or three specific malignancy types (oesophageal, prostate and haematological).
Member, Colorectal & GI Cancer Research Group (Proposed), Speculative idea to cluster PI's around collaborative study on Upper GI and Colon Cancers.Deliberately wide selection of surgeons, pathologists and academic researchers based on stated interest or publication in fields of oesophageal or colorectal cancer.
Member, PHG Funded PI's and Researchers, All Researchers funded under Cycle 3 PRTLI - Programme for Human Genomics
O'NEILL L., GUINAN E., DOYLE S., CONNOLLY D., O'SULLIVAN J., BENNETT A., SHEILL G., SEGURADO R., KNAPP P., FAIRMAN C., NORMAND C., GEOGHEGAN J., CONLON K., REYNOLDS JV., HUSSEY J., 'Rehabilitation strategies following oesophagogastric and hepatopancreaticobiliary cancer (ReStOre II): a protocol for a randomised controlled trial', 2020, -, Protocol or guideline, PUBLISHED  DOI
O'Neill L., Reynolds S., Sheill G., Guinan E., Mockler D., Geoghegan J., Conlon K., Reynolds, J.V., Hussey J., Physical function in patients with resectable cancer of the pancreas and liver-a systematic review, Journal of Cancer Survivorship, 2020, Journal Article, PUBLISHED  DOI
Sheill G., Guinan E., O'Neill L., Normand C., Doyle SL., Moore S., Newell J., McDermott G., Ryan R., Reynolds JV., Hussey J., Preoperative exercise to improve fitness in patients undergoing complex surgery for cancer of the lung or oesophagus (PREHIIT): protocol for a randomized controlled trial, BMC Cancer, 2020, Journal Article, PUBLISHED  DOI
Sheill G., Reynolds S., O'Neill L., Mockler D., Reynolds JV., Hussey J., Guinan E.,, Cardiopulmonary Exercise Testing in Oesophagogastric Surgery: a Systematic Review, Cardiopulmonary Exercise Testing in Oesophagogastric Surgery: a Systematic Review, 2020, p12 , Journal Article, PUBLISHED  DOI
O'Neill L., Knapp P., Doyle SL., Guinan E., Parker A.,Segurado R., Connolly D., O'Sullivan J., Reynolds JV., Hussey J, 'Patient and family co-developed participant information to improve recruitment rates, retention, and patient understanding in the Rehabilitation Strategies Following Oesophago-gastric and Hepatopancreaticobiliary Cancer (ReStOre II) trial: Protocol for a study within a trial (SWAT) [version 1; peer review: awaiting peer review]', 2019, -, Protocol or guideline, PUBLISHED  DOI
Guinan, E.M., Bennett, A.E., Doyle, S.L., O'Neill, L, Gannon, J., Foley, G., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Measuring the impact of oesophagectomy on physical functioning and physical activity participation: a prospective study, BMC Cancer, 19, (682), 2019, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Hagens, E.R.C. and Van Berge Henegouwen, M.I. and Van Sandick, J.W. and Cuesta, M.A. and Van Der Peet, D.L. and Heisterkamp, J. and Nieuwenhuijzen, G.A.P. and Rosman, C. and Scheepers, J.J.G. and Sosef, M.N. and Van Hillegersberg, R. and Lagarde, S.M. and Nilsson, M. and RÀsÀnen, J. and Nafteux, P. and Pattyn, P. and Hölscher, A.H. and Schröder, W. and Schneider, P.M. and Mariette, C. and Castoro, C. and Bonavina, L. and Rosati, R. and De Manzoni, G. and Mattioli, S. and Garcia, J.R. and Pera, M. and Griffin, M. and Wilkerson, P. and Chaudry, M.A. and Sgromo, B. and Tucker, O. and Cheong, E. and Moorthy, K. and Walsh, T.N. and Reynolds, J. and Tachimori, Y. and Inoue, H. and Matsubara, H. and Kosugi, S.-I. and Chen, H. and Law, S.Y.K. and Pramesh, C.S. and Puntambekar, S.P. and Murthy, S. and Linden, P. and Hofstetter, W.L. and Kuppusamy, M.K. and Shen, K.R. and Darling, G.E. and Sabino, F.D. and Grimminger, P.P. and Meijer, S.L. and Bergman, J.J.G.H.M. and Hulshof, M.C.C.M. and Van Laarhoven, H.W.M. and Mearadji, B. and Bennink, R.J. and Annema, J.T. and Dijkgraaf, M.G.W. and Gisbertz, S.S., Distribution of lymph node metastases in esophageal carcinoma [TIGER study]: Study protocol of a multinational observational study, BMC Cancer, 19, (1), 2019, Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Elliott, J.A. and O'Byrne, L. and Foley, G. and Murphy, C.F. and Doyle, S.L. and King, S. and Guinan, E.M. and Ravi, N. and Reynolds, J.V., Effect of neoadjuvant chemoradiation on preoperative pulmonary physiology, postoperative respiratory complications and quality of life in patients with oesophageal cancer, British Journal of Surgery, 2019, Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Melo, Ashanty M., O'Brien, Aisling M., Phelan, James J., Kennedy, Susan A., Wood, Nicole A. W., Veerapen, Natacha, Besra, Gurdyal S., Clarke, Niamh E., Foley, Emma K., Ravi, Akshaya, MacCarthy, Finbar, O'Toole, Dermot, Ravi, Narayamasami, Reynolds, John V., Conroy, Melissa J., Hogan, Andrew E., O'Sullivan, Jacintha, Dunne, Margaret R., Mucosal-Associated Invariant T Cells Display Diminished Effector Capacity in Oesophageal Adenocarcinoma, Frontiers in Immunology, 10, 2019, Journal Article, PUBLISHED  TARA - Full Text  DOI
Bundred, J.R. and Kamarajah, S.K. and Siaw-Acheampong, K. and Nepogodiev, D. and Jefferies, B. and Singh, P. and Evans, R. and Griffiths, E.A. and Alderson, D. and Gossage, J. and McKay, S. and Mohamed, I. and van Hillegersberg, R. and Vohra, R. and Wanigsooriya, K. and Whitehouse, T. and Bagajevas, A. and Bekele, A. and Blanco-Colino, R. and Da Roit, A. and El Kafsi-Mawley, J. and Gjata, A. and Gockel, I. and Castro, R.G. and Harustiak, T. and Hsu, P.-K. and Isik, A. and Kechagias, A. and Kennedy, A. and Kidane, B. and Mahendran, H.A. and Mejia, L. and Moreno, J.I. and Negoi, I. and Santiago, A.J. and Sayyed, R. and Schneider, P. and Soares, A.S. and Sousa, M. and Takeda, F.R. and Vanstraten, S. and Wallner, B. and Wijnhoven, B. and Achiam, M. and Agustin, T. and Akbar, A. and Al-Bahrani, A. and Al-Khyatt, W. and Albertsmeier, M. and Alghunaim, E. and Alkhaffaf, B. and Allum, W. and Am, F. and Andreollo, N. and Arndt, A. and Babor, R. and Barbosa, J. and Bardini, R. and Beardsmore, D. and Beban, G. and Bernardes, A. and Berrisford, R. and Bianchi, A. and Bjelovic, M. and Boddy, A. and Bolca, C. and Bonavina, L. and Bryce, G. and Byrom, R. and Casaca, R. and Chan, D. and Charalabopoulos, A. and Cheong, E. and Ciotola, F. and Colak, E. and Collins, C. and Constantinoiu, S. and Costa, R. and Dahlke, M. and Darling, G. and Dawas, K. and de Manzoni, G. and Denewer, A. and Devadas, M. and Dexter, S. and Dikinis, S. and Dimitrios, T. and Dolan, J. and Duong, C. and Egberts, J.-H. and Elgharably, Y. and Elhadi, M. and Elmahi, S. and Farias, F.A. and Fekaj, E. and Fernández, J. and Forshaw, M. and Freire, J. and French, D. and Gacevski, G. and Gaedcke, J. and Gananadha, S. and Gijon, M.M. and Gokhale, J. and Gordon, A. and Grimminger, P. and Guevara, R. and Guner, A. and Gutknecht, S. and Mahmoodzadeh, H. and Halldestam, I. and Hedberg, J. and Heisterkamp, J. and Higgs, S. and Hii, M. and Hindmarsh, A. and Hoppner, J. and Isaza, A. and Izbicki, J. and Jacobs, R. and Jain, P. and Johansson, J. and Johnston, B. and Kafsi, J. and Kassa, S. and Kelty, C. and Khan, I. and Khoo, D. and Khyatt, S. and Kjaer, D. and Korkolis, D. and Kreuser, N. and Larsen, M. and Lau, P. and Leite, J. and Lewis, W. and Liakakos, T. and Loureiro, C. and Mahendran, A. and Maynard, N. and Mcgregor, R. and Mcnally, S. and Medina-Franco, H. and Meguid, R. and Melhado, R. and Mercer, S. and Migliore, M. and Mingol, F. and Mogoanta, S. and Mohri, Y. and Mönig, S. and Moreno, J. and Motas, N. and Murphy, T. and Naqi, S. and Ni, R. and Niazi, S. and Oglesby, S. and Okonta, K. and Ortiz, S.R. and Pal, K. and Palazzo, F. and Pascher, A. and Pascual, M. and Pata, G. and Pera, M. and Puig, S. and Ramirez, J. and Raptis, D. and RÀsÀnen, J. and Reim, D. and Reynolds, J. and Robb, W. and Robertson, K. and Rosero, G. and Rosman, C. and Rossaak, J. and Saarnio, J. and Santiago, A. and Schiesser, M. and Scurtu, R.-R. and Sekhniaidze, D. and Sevinç, B. and Skipworth, R. and So, J. and Trugeda, M.S. and Syed, A. and Takahashi, A.M.L. and Takeda, F. and Talbot, M. and Tareen, M. and Terashima, M. and Testini, M. and Tewari, N. and Tez, M. and Thomas, M. and Tirnaksiz, M. and Tonini, V. and Tu, C.-C. and Turner, P. and Underwood, T. and Uzair, A. and Vallve-Bernal, M. and Valmasoni, M. and Vicente, C. and Videira, J.F. and Viswanath, Y. and Weindelmayer, J. and White, R. and Wigle, D. and Wilkerson, P. and Wills, V. and Zacharakis, E. and Zuluaga, M., International Variation in Surgical Practices in Units Performing Oesophagectomy for Oesophageal Cancer: A Unit Survey from the Oesophago-Gastric Anastomosis Audit (OGAA), World Journal of Surgery, 2019, Notes: [cited By 0], Journal Article, PUBLISHED  DOI

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Anti-oxidants in inflammatory disease. Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus. Liver and gut immune function in patients undergoing complex major surgery. Molecular predictors of response and resistance to chemotherapy and radiation therapy. Transcription factors in inflammation and neoplasia of the oesophagus. Upper gastrointestinal physiology.