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Professor John Reynolds

Professor & Head of Department (Surgery)

  Anti-oxidants in inflammatory disease   Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus   Liver and gut immune function in patients undergoing complex major surgery   Molecular predictors of response and resistance to chemotherapy and radiation therapy   Transcription factors in inflammation and neoplasia of the oesophagus   Upper gastrointestinal physiology
Details Date
Member, DMMC Inflammation, Immunity & Infection Principal Investigators, DMMC Principal Investigators leading research in inflammation, immunit and infection.
Member, Centre for Molecular Research in Cancer (Proposed), This consortium combines researchers with common interest in understanding cell cycle signaling and regulation with specific focus on two key cancer-related processes (cell cycle control, apoptosis) and/or three specific malignancy types (oesophageal, prostate and haematological).
Member, Colorectal & GI Cancer Research Group (Proposed), Speculative idea to cluster PI's around collaborative study on Upper GI and Colon Cancers.Deliberately wide selection of surgeons, pathologists and academic researchers based on stated interest or publication in fields of oesophageal or colorectal cancer.
Member, PHG Funded PI's and Researchers, All Researchers funded under Cycle 3 PRTLI - Programme for Human Genomics
Bennett, A.E., O'Neill, L., Connolly, D., Guinan, E.M., Boland, L., Doyle, S.L., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Patient experiences of a physiotherapy-led multidisciplinary rehabilitative intervention after successful treatment for oesophago-gastric cancer, Supportive Care in Cancer, 26, (8), 2018, p2615 - 2623, Journal Article, PUBLISHED  DOI  URL
Sheil, F. and Donohoe, C.L. and King, S. and O†Toole, D. and Cunningham, M. and Cuffe, S. and Ravi, N. and Reynolds, J.V., Outcomes for Esophageal Squamous Cell Carcinoma Treated with Curative Intent in a Western Cohort: Should Multimodal Therapy Be the Gold Standard?, World Journal of Surgery, 2018, p1485-1495 , Journal Article, PUBLISHED  DOI
O'Neill, L.M., Guinan, E., Doyle, S.L., Bennett, A.E., Murphy, C., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., Hussey, J., The RESTORE Randomized Controlled Trial: Impact of a multidisciplinary rehabilitative program on cardiorespiratory fitness in esophagogastric cancer survivorship, Annals of Surgery, 2018, p1 - 9, Journal Article, PUBLISHED  DOI  URL
O†Neill, L. and Moran, J. and Guinan, E.M. and Reynolds, J.V. and Hussey, J., Physical decline and its implications in the management of oesophageal and gastric cancer: a systematic review, Journal of Cancer Survivorship, 12, (4), 2018, p601-618 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
O†sullivan, K.E. and Michielsen, A.J. and O†regan, E. and Cathcart, M.C. and Moore, G. and Breen, E. and Segurado, R. and Reynolds, J.V. and Lysaght, J. and O†sullivan, J., pSTAT3 levels have divergent expression patterns and associations with survival in squamous cell carcinoma and adenocarcinoma of the oesophagus, International Journal of Molecular Sciences, 19, (6), 2018, p1720-, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
Baiocchi, G.L. and Giacopuzzi, S. and Marrelli, D. and Reim, D. and Piessen, G. and Matos da Costa, P. and Reynolds, J.V. and Meyer, H.-J. and Morgagni, P. and Gockel, I. and Lara Santos, L. and Jensen, L.S. and Murphy, T. and Preston, S.R. and Ter-Ovanesov, M. and Fumagalli Romario, U. and Degiuli, M. and Kielan, W. and Mönig, S. and KoÅ'odziejczyk, P. and Polkowski, W. and Hardwick, R. and Pera, M. and Johansson, J. and Schneider, P.M. and de Steur, W.O. and Gisbertz, S.S. and Hartgrink, H. and van Sandick, J.W. and Portolani, N. and Hölscher, A.H. and Botticini, M. and Roviello, F. and Mariette, C. and Allum, W. and de Manzoni, G., International consensus on a complications list after gastrectomy for cancer, Gastric Cancer, 2018, p1-18 , Notes: [cited By 0; Article in Press], Journal Article, PUBLISHED  DOI
Galvin KC, Conroy MJ, Doyle SL, Dunne MR, Fahey R, Foley E, O'Sullivan KE, Doherty DG, Geoghegan JG, Ravi N, O'Farrelly C, Reynolds JV, Lysaght J, Extratumoral PD-1 blockade does not perpetuate obesity-associated inflammation in esophageal adenocarcinoma, Cancer Letters, 418, 2018, 230 - 238, Journal Article, PUBLISHED  URL
Valkenet, K. and Trappenburg, J.C.A. and Ruurda, J.P. and Guinan, E.M. and Reynolds, J.V. and Nafteux, P. and Fontaine, M. and Rodrigo, H.E. and van der Peet, D.L. and Hania, S.W. and Sosef, M.N. and Willms, J. and Rosman, C. and Pieters, H. and Scheepers, J.J.G. and Faber, T. and Kouwenhoven, E.A. and Tinselboer, M. and RÀsÀnen, J. and RyynÀnen, H. and Gosselink, R. and van Hillegersberg, R. and Backx, F.J.G., Multicentre randomized clinical trial of inspiratory muscle training versus usual care before surgery for oesophageal cancer, British Journal of Surgery, 105, (5), 2018, p502-511 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Bell, A. and Conway, N. and Courtney, J. and Kennedy, K. and Raubenheimer, Z. and Rice, N. and Kevans, D. and Donohoe, C.L. and Reynolds, J.V., Point prevalence of adult intestinal failure in Republic of Ireland, Irish Medical Journal, 111, (2), 2018, p688 , Notes: [cited By 0], Journal Article, PUBLISHED
Brookes, S.T. and Chalmers, K.A. and Avery, K.N.L. and Coulman, K. and Blazeby, J.M. and Alderson, D. and Whiting, J. and Alkhaffaf, B. and Allum, W. and Attwood, S. and Barr, H. and Hewin, D. and Higgs, S. and Vipond, M. and Batiwalla, I. and Blackshaw, G. and Bolter, M. and Goulding, C. and Berrisford, R. and Sanders, G. and Wheatley, T. and Botha, A. and Mason, R. and Byrne, J. and Kelly, J. and Callan, J. and Couper, G. and Deans, C. and Paterson-Brown, S. and Dawas, K. and Mughal, M. and Galloway, S. and George, M. and Gokhale, J. and Goodman, M. and Hardwick, R. and Hassn, A. and Henwood, M. and Kryzstopik, R. and Lewis, M. and Tallett, J. and MacKay, C. and Manson, J. and Moxon, R. and Osborne, S. and Page, R. and Shackcloth, M. and Parameswaran, R. and Parsons, S. and Welch, N. and Phillips, A. and Sgromo, B. and Preston, S. and Pursnani, K. and Ward, J. and Reynolds, J. and Titcomb, D. and Barham, C.P. and Falk, S. and Hollowood, A. and Tucker, O. and Underwood, T. and Vickers, J. and Walker, L. and Price, J. and Sedman, P. and Walsh, T. and Donovan, J. and Noble, S. and Elliott, J. and Goldin, R. and Hanna, G., Impact of question order on prioritisation of outcomes in the development of a core outcome set: A randomised controlled trial, Trials, 19, (1), 2018, Notes: [cited By 1], Journal Article, PUBLISHED  DOI

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Anti-oxidants in inflammatory disease. Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus. Liver and gut immune function in patients undergoing complex major surgery. Molecular predictors of response and resistance to chemotherapy and radiation therapy. Transcription factors in inflammation and neoplasia of the oesophagus. Upper gastrointestinal physiology.