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Professor John Reynolds

Professor & Head of Department (Surgery)
TRINITY CENTRE, S J H


  Anti-oxidants in inflammatory disease   Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus   Liver and gut immune function in patients undergoing complex major surgery   Molecular predictors of response and resistance to chemotherapy and radiation therapy   Transcription factors in inflammation and neoplasia of the oesophagus   Upper gastrointestinal physiology
Details Date
Member, DMMC Inflammation, Immunity & Infection Principal Investigators, DMMC Principal Investigators leading research in inflammation, immunit and infection.
Member, Centre for Molecular Research in Cancer (Proposed), This consortium combines researchers with common interest in understanding cell cycle signaling and regulation with specific focus on two key cancer-related processes (cell cycle control, apoptosis) and/or three specific malignancy types (oesophageal, prostate and haematological).
Member, Colorectal & GI Cancer Research Group (Proposed), Speculative idea to cluster PI's around collaborative study on Upper GI and Colon Cancers.Deliberately wide selection of surgeons, pathologists and academic researchers based on stated interest or publication in fields of oesophageal or colorectal cancer.
Member, PHG Funded PI's and Researchers, All Researchers funded under Cycle 3 PRTLI - Programme for Human Genomics
Low DE, Alderson D, Cecconello I, Chang AC, Darling GE, D"Journo XB, Griffin SM, Hölscher AH, Hofstetter WL, Jobe BA, Kitagawa Y, Kucharczuk JC, Law SY, Lerut TE, Maynard N, Pera M, Peters JH, Pramesh CS, Reynolds JV, Smithers BM, van Lanschot JJ, International Consensus on Standardization of Data Collection for Complications Associated With Esophagectomy: Esophagectomy Complications Consensus Group (ECCG)., Annals of surgery, 2015, Journal Article, PUBLISHED
Abdel-Latif MM, Kelleher D, Reynolds JV, Molecular mechanisms of constitutive and inducible NF-kappaB activation in oesophageal adenocarcinoma., European journal of cancer (Oxford, England : 1990), 2015, Journal Article, PUBLISHED
Palles C, Chegwidden L, Li X, Findlay JM, Farnham G, Castro Giner F, Peppelenbosch MP, Kovac M, Adams CL, Prenen H, Briggs S, Harrison R, Sanders S, MacDonald D, Haigh C, Tucker A, Love S, Nanji M, deCaestecker J, Ferry D, Rathbone B, Hapeshi J, Barr H, Moayyedi P, Watson P, Zietek B, Maroo N, Gay L, Underwood T, Boulter L, McMurtry H, Monk D, Patel P, Ragunath K, Al Dulaimi D, Murray I, Koss K, Veitch A, Trudgill N, Nwokolo C, Rembacken B, Atherfold P, Green E, Ang Y, Kuipers EJ, Chow W, Paterson S, Kadri S, Beales I, Grimley C, Mullins P, Beckett C, Farrant M, Dixon A, Kelly S, Johnson M, Wajed S, Dhar A, Sawyer E, Roylance R, Onstad L, Gammon MD, Corley DA, Shaheen NJ, Bird NC, Hardie LJ, Reid BJ, Ye W, Liu G, Romero Y, Bernstein L, Wu AH, Casson AG, Fitzgerald R, Whiteman DC, Risch HA, Levine DM, Vaughan TL, Verhaar AP, van den Brande J, Toxopeus EL, Spaander MC, Wijnhoven BP, van der Laan LJ, Krishnadath K, Wijmenga C, Trynka G, McManus R, Reynolds JV, O'Sullivan J, MacMathuna P, McGarrigle SA, Kelleher D, Vermeire S, Cleynen I, Bisschops R, Tomlinson I, Jankowski J, Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett's Esophagus., Gastroenterology, 148, (2), 2015, p367-78 , Journal Article, PUBLISHED  TARA - Full Text  DOI
de Steur, W. O. Henneman, D. Allum, W. H. Dikken, J. L. van Sandick, J. W. Reynolds, J. Mariette, C. Jensen, L. Johansson, J. Kolodziejczyk, P. Hardwick, R. H. van de Velde, C. J. H., Common data items in seven European oesophagogastric cancer surgery registries: Towards a European Upper GI Cancer Audit (EURECCA Upper GI), European Journal of Surgical Oncology (EJSO), 40, (3), 2014, p325 - 329, Journal Article, PUBLISHED  TARA - Full Text
Da Mota, Benoit Fritsch, Virgile Varoquaux, Gaël Banaschewski, Tobias Barker, Gareth J. Bokde, Arun L. W. Bromberg, Uli Conrod, Patricia Gallinat, Jürgen Garavan, Hugh Martinot, Jean-Luc Nees, Frauke Paus, Tomas Pausova, Zdenka Rietschel, Marcella Smolka, Michael N. Ströhle, Andreas Frouin, Vincent Poline, Jean-Baptiste Thirion, Bertrand, Randomized parcellation based inference, NeuroImage, 2014, Journal Article, PUBLISHED
Kavanagh, M.E., O'Sullivan, K.E., O'Hanlon, C., (...), Lysaght, J., Reynolds, J.V., The esophagitis to adenocarcinoma sequence; the role of inflammation, Cancer Letters, 345, (2), 2014, p182-189 , Journal Article, PUBLISHED  DOI
O'Sullivan KE, Reynolds JV, O'Hanlon C, O'Sullivan JN, Lysaght J, Could signal transducer and activator of transcription 3 be a therapeutic target in obesity-related gastrointestinal malignancy?, Journal of gastrointestinal cancer, 45, (1), 2014, p1-11 , Journal Article, PUBLISHED  DOI
Donohoe CL, Reynolds JV, Defining a successful esophagectomy., Annals of surgery, 259, (5), 2014, pe82 , Journal Article, PUBLISHED  DOI
Howard JM, Cathcart MC, Healy L, Beddy P, Muldoon C, Pidgeon GP, Reynolds JV, Leptin and adiponectin receptor expression in oesophageal cancer., The British journal of surgery, 101, (6), 2014, p643-52 , Journal Article, PUBLISHED  DOI
Valkenet K, Trappenburg JC, Gosselink R, Sosef MN, Willms J, Rosman C, Pieters H, Scheepers JJ, de Heus SC, Reynolds JV, Guinan E, Ruurda JP, Rodrigo EH, Nafteux P, Fontaine M, Kouwenhoven EA, Kerkemeyer M, van der Peet DL, Hania SW, van Hillegersberg R, Backx FJ, Preoperative inspiratory muscle training to prevent postoperative pulmonary complications in patients undergoing esophageal resection (PREPARE study): study protocol for a randomized controlled trial., Trials, 15, (1), 2014, p144 , Journal Article, PUBLISHED  TARA - Full Text  DOI
  

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Anti-oxidants in inflammatory disease. Genetic polymorphisms in upper gastrointestinal cancer and Barrett's oesophagus. Liver and gut immune function in patients undergoing complex major surgery. Molecular predictors of response and resistance to chemotherapy and radiation therapy. Transcription factors in inflammation and neoplasia of the oesophagus. Upper gastrointestinal physiology.