Skip to main content

Trinity College Dublin, The University of Dublin

Menu Search


Trinity College Dublin By using this website you consent to the use of cookies in accordance with the Trinity cookie policy. For more information on cookies see our cookie policy.

      
Profile Photo

Professor Padraic Fallon

Professor of Translational Immunology (Clinical Medicine)
Interim IMM Director (Molecular Medicine Ireland)
      
Profile Photo

Professor Padraic Fallon

Professor of Translational Immunology (Clinical Medicine)

 pfallon@tcd.ie

 3531896 3297

Interim IMM Director (Molecular Medicine Ireland)


Professor Padraic Fallon is Dean of the Faculty of Health Sciences and Professor of Translational Immunology at the School of Medicine. Prof. Fallon has 30 years of experience in academic research and leadership, including as a Wellcome Trust Fellow (University of Cambridge, UK) and a NATO Visiting Scientist (Cornell University, USA). Leadership roles include Associate Dean of Research (TCD), and he is the current Director of the all-island Irish Clinical Academic Training Programme (ICAT). Prof. Fallon has supervised over 30 MSc and 13 PhD students and mentored >30 Postdoctoral fellows. Fallon is a key opinion leader in translational immunology, having made several seminal contributions to the field. He has been ranked in the top 1% of scientists worldwide by citations in immunology (Clarivate). He is an author of over 230 peer- reviewed publications. Examples from TCD include: Nature (2008, 2010, 2014, 2018, 2026); Science (2012, 2024); Science Immunology (2022); Cell (2018); Science Translational Medicine (2014, 2015, 2016, 2022, 2023); Proceedings of the National Academy of Sciences (2013, 2013,2014); Immunity (2002, 2014, 2016, 2017, 2018, 2019, 2020, 2026); and Nature Communications (2012, 2015, 2016, 2015, 2019, 2019, 2019,2023, 2024); Blood (2009, 2016, 2018, 2025). Professor Fallon has secured over €20 million in research funding as Principal Investigator (Science Foundation Ireland, Wellcome Trust, EU, Health Research Board and industry) and an additional €120 million as co- applicant, supporting extensive programmes across immunology, infection, and inflammatory disease. In 2026, Prof. Fallon is PI on a Research Ireland award and is a co- applicant on Rinn Advanced Therapies (€51 million) and a PI on Rinn Medical Devices (€64 million). Prof. Fallon serves on national bodies, such as the Board of Dublin Dental University Hospital, and on international agencies, e.g. ERC grant panels. Fallon has received various awards, including an SFI Stokes Professorship (2008), Membership of the Royal Irish Academy (2014), and Doctor of Science (University of Wales, UK, 2015).
  Allergies   ALLERGY   Animal Models   ANIMAL-MODELS   Asthma   CYTOKINE RESPONSES   DISEASE MODELS   EXPERIMENTAL COLITIS   Helminths   Immunotherapies   INFECTION   Inflammatory Bowel Disease   MATERNAL-FETAL INTERFACE   Parasites   Transgenic Mice
Dyer AH, Dolphin H, Morrison L, Kenny T, Fallon PG, Cunningham C, O'Connor A, Lawlor B, O'Farrelly C, Bourke NM, Kennelly SP, NILVAD Study Group, Systemic inflammation, delirium and clinical progression in mild-moderate Alzheimer disease., EBioMedicine, 2026, Journal Article, PUBLISHED  DOI
Alexandre Fagnan, Cristina Di Genua, Yiran Meng, Roy Drissen, Zishan Zhang, Bo Zhang, Padraic G. Fallon, Vassilis Pachnis, Erika J. Mancini, Fränze Progatzky, Claus Nerlov, A mechanism to initiate emergency type 2 myelopoiesis, Nature, 653, (8113), 2026, p212 - 220, p212-220 , Journal Article, PUBLISHED  DOI
Heike C. Hawerkamp, Aoife Yeow, Ciara Byrne, Anne Chevalier, Laura Matarazzo, AJ Lawrence, Daniel Ivers, Tatenda Murangi, Niamh A. O"Dowd, Anne"Marije Hulshof, Ferdows Atiq, Jamie M. O"Sullivan, Vincent P. Kelly, Conor M. Finlay, Henry J. McSorley, Bagirath Gangadharan, Birgit M. Reipert, James S. O"Donnell, Peter L. Turecek, Padraic G. Fallon, The interleukin-33 receptor (ST2) is a novel therapeutic target to attenuate the progression of hemophilic arthropathy, Blood, 146, (16), 2025, p1979 - 1990, p1979-1990 , Journal Article, PUBLISHED  DOI
Alicia Martinek, Andrea Deinzer, Roman G. Gerlach, Jana Petzold, Lea Semmler, Christof Vorsatz, Padraic G. Fallon, Christian Schwartz, Obesity Impairs Skin Barrier Function and Facilitates Allergic Sensitization in Mice, Allergy, 81, (2), 2025, p498 - 512, p498-512 , Journal Article, PUBLISHED  DOI
Yin M, Wadhwa R, Marshall JE, Gillis CM, Kim RY, Dua K, Palsson-McDermott EM, Fallon PG, Hansbro PM, O'Neill LAJ., 4-Octyl Itaconate Alleviates Airway Eosinophilic Inflammation by Suppressing Chemokines and Eosinophil Development., Journal of immunology (Baltimore, Md. : 1950), 212, (1), 2024, p13-23 , Journal Article, PUBLISHED  DOI
Szeto ACH, Clark PA, Ferreira ACF, Heycock M, Griffiths EL, Jou E, Mannion J, Luan SL, Storrar S, Knolle MD, Kozik P, Jolin HE, Fallon PG, McKenzie ANJ., Mef2d potentiates type-2 immune responses and allergic lung inflammation., Science (New York, N.Y.), 384, (6703), 2024, peadl0370 , Journal Article, PUBLISHED  DOI
Tchen J, Simon Q, Chapart L, Thaminy MK, Vibhushan S, Saveanu L, Lamri Y, Saidoune F, Pacreau E, Pellefigues C, Bex-Coudrat J, Karasuyama H, Miyake K, Hidalgo J, Fallon PG, Papo T, Blank U, Benhamou M, Hanouna G, Sacre K, Daugas E, Charles N., PD-L1- and IL-4-expressing basophils promote pathogenic accumulation of T follicular helper cells in lupus., Nature communications, 15, (1), 2024, p3389 , Journal Article, PUBLISHED  DOI
Schneider AK, Domingos-Pereira S, Cesson V, Polak L, Fallon PG, Zhu J, Roth B, Nardelli-Haefliger D, Derré L., Type 2 innate lymphoid cells are not involved in mouse bladder tumor development, Frontiers in Immunology, 14, 2024, p1335326 , Notes: [DOI: 10.3389/fimmu.2023.1335326], Journal Article, PUBLISHED  DOI
Dwivedi, A. and Mhaonaigh, A.U. and Carroll, M. and Khosravi, B. and Batten, I. and Ballantine, R.S. and Phelan, S.H. and O†Doherty, L. and George, A.M. and Sui, J. and Hawerkamp, H.C. and Fallon, P.G. and Noppe, E. and Mason, S. and Conlon, N. and Cheallaigh, C.N. and Finlay, C.M. and Little, M.A., Emergence of dysfunctional neutrophils with a defect in arginase-1 release in severe COVID-19, JCI Insight, 9, (17), 2024, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
Michelle E. Armstrong, Aoife McElroy, Rosangela Invernizzi, Joanna Laskowska, Aisling O"Neill, Mohammad Doroudian, Andrew Bowie, Padraic G. Fallon, Toby M. Maher, Cory M. Hogaboam, Philip L. Molyneaux, Nik Hirani, Seamas C. Donnelly, Toll-like Receptor 3 Leu412Phe: A Candidate Polymorphism in Lung Microbiome Dysregulation and Acute Exacerbation in Idiopathic Pulmonary Fibrosis Patients, 2024, pA4889 - A4889, pA4889-A4889 , Journal Article, PUBLISHED  DOI
  

Page 1 of 26

  


Award Date
Member Royal Irish Academy (MRIA) 2014
Doctor of Science 2015
Stokes Professorship from Science Foundation Ireland. 2008
Fellow Trinity College Dublin (FTCD) 2009
RESEARCH Research involves overlapping translational immunology themes. i. Using mice as models, transgenics and mutant strains, to study basic innate and adaptive immunity mechanisms in inflammatory and infectious diseases. ii. Immune phenotyping of patients with inflammatory diseases such as atopic dermatitis, asthma and pulmonary fibrosis. iii. Research on inflammatory diseases of patients across the lifespan, from skin diseases in infants and asthma in adults to metabolic syndrome in the elderly. Research aims to elucidate novel mechanisms that modulate innate and adaptive cellular immunity, thereby altering inflammation and offering therapeutic potential. The primary diseases addressed are fibrotic disorders, allergic lung and skin inflammation, and inflammatory bowel disease. A growing emphasis is placed on applying extensive expertise in animal models of human inflammatory diseases and the general pathophysiology of inflammation to the functional analysis of new therapeutic molecules/strategies, in collaboration with clinical partners and pharma.