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Professor Juliette Hussey

Vice President Global Relations (TCD Global)
EAST THEATRE

Professor (Physiotherapy)

Professor Hussey has been in Trinity for over 20 years and was head of the discipline of Physiotherapy from 2003-2014. During that time she led on developing programmes in Physiotherapy and allied health sciences which are delivered in Singapore. She was elected to fellowship in 2011, promoted to associate professor in 2006 and to Professor in 2015. She is currently in her second term in the position of Vice President for Global Relations. As well as being a college officer for the last four years Professor Hussey leads a group working in the area of exercise rehabilitation in patients with cancer. Her research is translational and is aimed at scientifically improving exercise prescription to optimise therapeutic responses. This includes evaluating means of improving physical capacity preoperatively to reduce postoperative morbidity for patients undergoing complex cancer surgery. A challenge in the area of exercise and cancer is to determine underlying mechanisms and her group is working with clinical scientists in this respect. Her current research in oesophageal, hepatopancreaticobiliary and thoracic cancer is funded by the Health Research Board and the Irish Cancer Society. Recently completed work in the areas of oesophageal and prostate cancer was funded by the Health Research Board and the World Cancer Research Fund. Professor Hussey has a strong publication record which numbers over 70 full paper publications. In addition, she has co-edited three books and 12 book chapters. In terms of research supervision, she has supervised 30 post graduate students to completion ( 9 PhD and 21 MSc).
 Rehabilitation strategies following oesphagogastric and hepatopancreaticobiliary cancer
 Preoperative exercise to improve fitness in patients undergoing complex surgery for cancer of the lung or oesphagus
 Rehabilitation following Oesphageal Cancer: Identifying Rehabiltative Needs and Strategies
 
 Evasion of immune editing by circulating tumour cells is an exercise modifiable mechanism in obese men with prostate cance ( ExPeCT)

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Details Date
External Examiner to three MScs in University College London 2016-2019
Member of the Irish Cancer Society- Cancer Support Committee 2017-present
Representative for allied health professions on HSE Education, Research and Training Committee 2008-2010
Member Scientific Advisory Committee of the second phase of the National Longitudinal Study in Children (TCD/ESRI) 2014
Sole allied health representative on the Research and Education Committees of the National Children's Hopspital 2009-2012
Member of the Department of Health Therapy Research Strategy Committee tasked with developing a research strategy for allied health professions in Ireland 2008
Member of the Health Service Executive Steering Group fore the Therapy Project Office 2007
Judging panel Irish Undergraduate Awards 2009
Founding member of the Rehabilitation and Therapy Research Society and Treasurer of the Society 2007
Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
French Fluent Medium Fluent
Details Date From Date To
Member of the Irish Society of Chartered Physiotherapists 1983 Present
Guinan, E.M., Bennett, A.E., Doyle, S.L., O'Neill, L, Gannon, J., Foley, G., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Measuring the impact of oesophagectomy on physical functioning and physical activity participation: a prospective study, BMC Cancer, 19, (682), 2019, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Brady L, Sheil G, Baird AM, Allott EH, Vlajnic T, Greene J, Casey O, Hussey J, Examining the link between obesity, inflammation, and exercise in patients with metastatic prostate cancer- an interim analysis from the ExPeCT trial, Cancer Research, 78, 2018, ppA057 - A057, Conference Paper, PUBLISHED
Sheil G, Brady L, Guinan EM,Hussey J, Hevey D, Vlanjic T, Casey O, Lifestyle and health related quality of life in men with metastatic prostate cancer, Cancer Research, 78, 2018, ppA059 - A059, Conference Paper, PUBLISHED
Sheill G, Guinan E, Neill LO, Hevey D, Hussey J, Physical activity and advanced cancer: The views of chartered physiotherapists in Ireland, Physiotherapy Theory and Practice, 2018, p1 - 8, Journal Article, PUBLISHED
Guinan, E.M., Doyle, S.L., Bennett, A.E., O'Neill, L, Gannon, J., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Sarcopenia during neoadjuvant therapy for oesophageal cancer: characterising the impact on muscle strength and physical performance, Supportive Care in Cancer, 26, (5), 2018, p1569 - 1576, Journal Article, PUBLISHED  DOI  URL
Bennett, A.E., O'Neill, L., Connolly, D., Guinan, E.M., Boland, L., Doyle, S.L., O'Sullivan, J., Reynolds, J.V., & Hussey, J., Patient experiences of a physiotherapy-led multidisciplinary rehabilitative intervention after successful treatment for oesophago-gastric cancer, Supportive Care in Cancer, 26, (8), 2018, p2615 - 2623, Journal Article, PUBLISHED  DOI  URL
O'Neill, L.M., Guinan, E., Doyle, S.L., Bennett, A.E., Murphy, C., Elliott, J.A., O'Sullivan, J., Reynolds, J.V., Hussey, J., The RESTORE Randomized Controlled Trial: Impact of a multidisciplinary rehabilitative program on cardiorespiratory fitness in esophagogastric cancer survivorship, Annals of Surgery, 268, (5), 2018, p747 - 755, Journal Article, PUBLISHED  DOI  URL
Mulcahy S, Prendergast J, Foley G, O'Hare A, Murphy E, Guinan EM, Hussey J, Exercise Rehabilitation services provided by physiotherapy departments in Ireland., Irish Medical Journal , 111, (9), 2018, Journal Article, PUBLISHED
Hussey JM, Yang T, Dowds J, O'Connor L, Reynolds JV, Guinan EM., Quantifying postoperative mobilisation following oesophagectomy., Physiotherapy, 2018, Journal Article, PUBLISHED  DOI
O'Neill, L. and Moran, J. and Guinan, E.M. and Reynolds, J.V. and Hussey, J., Physical decline and its implications in the management of oesophageal and gastric cancer: a systematic review, Journal of Cancer Survivorship, 12, (4), 2018, p601-618 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
  

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Research in cancer rehabilitation is a relatively recent but rapidly expanding field. In the last 20-30 years there have been significant advances in both diagnostics and therapeutic interventions for patients with cancer. An increasing number of people are successfully treated of their disease or are living with cancer. This has led to an increased population of cancer survivors many of whom have physical and psychological needs that require interventions in order to optimise quality of life. Physical functioning is effected by both the disease itself and the adverse side effects of treatment (surgery, chemotherapy, radiation) and we have shown in many studies that patients complete initial treatment with significantly reduced physical performance ( poor exercise tolerance, muscle weakness and lower levels of muscles mass with increased body fat). These impairments need to be managed to enable the patient to return to pre morbid functioning (e.g. manage daily life, return to participating in family life, return to work etc). In addition to optimising return to function addressing the adverse changes in body composition and physical performance may assist in the prevention of secondary disease particularly cardiovascular disease which cancer survivors are at a greater risk of developing. Over the last 12 years I have secured over 2m euro as PI in grant funding to support my research in this area. The research is multidisciplinary and is focused both on outcomes and underlying mechanisms ( working with clinical scientists). I have successfully supervised 30 post graduate students (nine PhD) and have published over 75 full papers and 100 scientific presentations at leading conferences internationally. My research achievements in this area need to be considered in the context of an emerging field of work and a very low research base in the discipline of Physiotherapy here and internationally. When I commenced in Trinity there were no academics with a PhD or active in research and no laboratory facilities. Along with a colleague I developed two self financing MSc programmes from which we were able to fund basic research equipment to investigate exercise responses and monitor physical activity. My current research is funded by the Health Research Board (rehabilitation strategies in oesophageal and hepatopancreaticobiliary cancer) and the Health Research Board/Irish Cancer Society (prehabilitation in oesophageal and thoracic surgery). I am part of a number of international research groups including TopCap a Cancer-Epidemiology group from Harvard, Trinity, UCD, Kings College London, and Upsalla and we were a partner on an EU funded study PREPARE led by Utrecht. I also am a co-investigator on HRB funded grant ( PI Joanne Lysaght) Elucidating the pathological role of obesity, inflammation, immunity in cancer related sarcopenia in upper gastrointestinal cancers (Euro 336,590). Recently completed research was funded by the HRB and WCRF ( World Cancer Research Fund)where I was a co-aplicant. I also collaborate in other clinical areas where the impact of exercise is being investigated such as the effect of exercise on cognitive function. I have collaborated with Prof Brian Lawlor and Prof Ian Robertson in developing exercise interventions for patients with cognitive impairment.