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Dr. Cara Martin

Assistant Professor (Histopathology)

Assistant Professor (Molecular Medicine Ireland)

Dr Cara Martin is an Assistant Professor in Molecular Pathology and Tumour Biology at the Department of Histopathology, Trinity College Dublin. She obtained her PhD from Trinity College in 2004, her MSc in Biotechnology from National University of Ireland, Galway in 1998, and BSc (Hons) from National University of Ireland, Galway in 1996. She currently leads the HPV Research Group based in Trinity College and the Coombe Women and Infant's University Hospital. Her research programme consists of translational health services based research and basic research approaches in female gynecological cancers, head and neck cancers and other HPV associated cancers. She is co-founder, lead investigator and programme manager of CERVIVA, The Irish Cervical Screening Research Consortium (, which is a health services based research program Cara leads the molecular epidemiology work packages within the various CERVIVA projects and is leading the HPV primary screening pilot study and the ECHO Study [Epidemiology of HPV in Oral Cancers in Ireland]. She was PI/co-ordinator on a number of European FP7 funded projects in the area of cervical cancer screening and diagnostics, including SYSTEMCERV, AUTOCAST and MicroActive. To date, she has published 81 peer reviewed publication and has filed 2 patents. Her-h index is 27 and she has >3500 citations.
  Apoptosis   Apoptosis, molecular control   Autism   Bioinformatics   Biology   Cancer genetics and cell biology including metastasis   Cell cycle control   Cervical cancer   Chromosome structure and dynamics   Commercialisation of scientific research   Community health and general practice   Cytology and Cancerology   DNA polymorphisms, evaluate chimerism after bone marrow transplant   DNA transcription and translation   DNA typing   Drug development and evaluation   Environmental Carcinogenesis   Epidemiology   Gene therapy   Gene transcription in human cancer   Genetic/Molecular epidemiology   Genomic structure and function, molecular approaches to gene function   Gynaecology oncology   Health attitudes and behaviour   Health management   Host, Pathogen interactions   Human genetics   Imaging Techniques   Infertility   Intra and intercellular signalling   Medical Sciences, Research   Medical technology   Membrane and protein trafficking   Molecular population genetics   Nuclei acid chemistry, structure and folding   Oncogenes, apoptosis and tumour development   Pathology   Population based intervention trials   Regulatory methods of gene expression   RNA processing, stability and degradation   Stem Cell biology and hematopoiesis   Therapeutic and Clinical oncology   Tumour immunology and immunotherapy   Virology and viral pathogenesis
 CERVIVA-Vax: Monitoring the impact of HPV vaccination in Ireland
 Enhancing the Evidence Base for Cost-Effectiveness Analysis in Ireland: Building Improvements from the Intervention-Specific to System-Wide Levels
 CERVIVA: The HPV Educate Project
 What influences cervical screening uptake in older women and how can screening programmes translate this knowledge into behaviour changing strategies? A CERVIVA-CervicalCheck co-production project
 CERVIVA studentship for ECHO study

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Traynor D, Kearney P, Ramos I, Martin CM, O'Leary JJ, Lyng FM., A study of hormonal effects in cervical smear samples using Raman spectroscopy., Journal of biophotonics, 2018, pe201700240-, Journal Article, PUBLISHED  DOI
Traynor D, Duraipandian S, Martin CM, O'Leary JJ, Lyng FM. , Improved removal of blood contamination from ThinPrep cervical cytology samples for Raman spectroscopic analysis, J Biomed Opt, 23, (5), 2018, Notes: [. J Biomed Opt. 2018 May;23(5):1-8. . PubMed PMID: 29729092. ], Journal Article, PUBLISHED
Kearney P, Traynor D, Bonnier F, Lyng FM, O'Leary JJ, Martin CM., Raman spectral signatures of cervical exfoliated cells from liquid-based cytology samples., Journal of biomedical optics, 22, (10), 2017, p1-10 , Journal Article, PUBLISHED  DOI
Varga N, Mózes J, Keegan H, White C, Kelly L, Pilkington L, Benczik M, Zsuzsanna S, Sobel G, Koiss R, Babarczi E, Nyíri M, Kovács L, Attila S, Kaltenecker B, Géresi A, Kocsis A, O'Leary J, Martin CM, Jeney C., The Value of a Novel Panel of Cervical Cancer Biomarkers for Triage of HPV Positive Patients and for Detecting Disease Progression., Pathology oncology research : POR, 23, (2), 2017, p295-305 , Journal Article, PUBLISHED  DOI
Woods RSR, Keegan H, White C, Tewari P, Toner M, Kennedy S, O'Regan EM, Martin CM, Timon CVI, O'Leary JJ., Cytokeratin 7 in Oropharyngeal Squamous Cell Carcinoma: A Junctional Biomarker for Human Papillomavirus-Related Tumors., Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 26, (5), 2017, p702-710 , Journal Article, PUBLISHED  DOI
O'Connor M, O'Brien K, Waller J, Gallagher P, D'Arcy T, Flannelly G, Martin CM, McRae J, Prendiville W, Ruttle C, White C, Pilkington L, O'Leary JJ, Sharp L, Irish Cervical Screening Research Consortium (CERVIVA)., Physical after-effects of colposcopy and related procedures, and their inter-relationship with psychological distress: a longitudinal survey., BJOG : an international journal of obstetrics and gynaecology, 124, (9), 2017, p1402-1410 , Journal Article, PUBLISHED  DOI
Ó Céilleachair A, O'Mahony JF, O'Connor M, O'Leary J, Normand C, Martin C, Sharp L., Health-related quality of life as measured by the EQ-5D in the prevention, screening and management of cervical disease: A systematic review., Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 26, (11), 2017, p2885-2897 , Journal Article, PUBLISHED  DOI
O'Connor M, Gallagher P, Waller J, Martin CM, O'Leary JJ, Sharp L, Irish Cervical Screening Research Consortium (CERVIVA)., Adverse psychological outcomes following colposcopy and related procedures: a systematic review., BJOG : an international journal of obstetrics and gynaecology, 123, (1), 2016, p24-38 , Journal Article, PUBLISHED  DOI
O'Connor M, O'Leary E, Waller J, Gallagher P, D'Arcy T, Flannelly G, Martin C.M, McRae J, Prendiville W, Ruttle C, White C, Pilkington L, O'Leary J.J, Sharp L, Trends in, and predictors of, anxiety and specific worries following colposcopy: A 12-month longitudinal study, Psycho-Oncology, 25, (5), 2016, p597 - 604, Notes: [Cited By :1 Export Date: 27 January 2017], Journal Article, PUBLISHED  DOI  URL
White C, Bakhiet S, Bates M, Keegan H, Pilkington L, Ruttle C, Sharp L, O' Toole S, Fitzpatrick M, Flannelly G, O' Leary JJ, Martin CM. , Triage of LSIL/ASC-US with p16/Ki-67 dual staining and human papillomavirus testing: a 2-year prospective study. , Cytopathology, 27, (4), 2016, p269 - 276, Journal Article, PUBLISHED

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Martin C, Astbury, K, O'Leary, JJ. , Molecular Biomarkers in Cervical Cancer, Cancerwise, 4, (2), 2005, p15 - 19, Journal Article, PUBLISHED