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Dr. Patrick Walsh

Associate Professor (Clinical Medicine)


  Immunology, Immunotherapy   Medicine
 Targetting the IL-36 pathway in IBD

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Details Date From Date To
International Cytokine Society 2018
Faculty member of F1000 Biology 2012
Irish Society of Immunology 2008
British Society of Immunology 2008
Leon G, Hussey S, Walsh PT., The Diverse Roles of the IL-36 Family in Gastrointestinal Inflammation and Resolution., Inflammatory bowel diseases, 27, (3), 2021, p440-450 , Journal Article, PUBLISHED  DOI
Interleukin-1 in, editor(s)Offermmans S and Rosenthal W , Encyclopedia of Molecular Pharmacology, Springer Reference, 2020, [Lucitt MB and Walsh PT], Book Chapter, PUBLISHED
Hernández-Santana YE, Leon G, St Leger D, Fallon PG, Walsh PT., Keratinocyte interleukin-36 receptor expression orchestrates psoriasiform inflammation in mice., Life Sci Alliance, 3, (4), 2020, Journal Article, PUBLISHED  DOI
Emma B. O'Connor, Natalia Muñoz-Wolf, Gemma Leon, Ed C. Lavelle, Kingston H. G. Mills, Patrick T. Walsh and Richard K. Porter, UCP3 reciprocally controls CD4+ Th17 and Treg cell differentiation, PLoS ONE, 15, (11), 2020, pe02-, Journal Article, PUBLISHED  TARA - Full Text  DOI
Giannoudaki E, Hernandez-Santana YE, Mulfaul K, Doyle SL, Hams E, Fallon PG, Mat A, O'Shea D, Kopf M, Hogan AE, Walsh PT., Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction., Nature communications, 10, (1), 2019, p4003 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Hernandez-Santana YE, Giannoudaki E, Leon G, Lucitt MB, Walsh PT., Current perspectives on the interleukin-1 family as targets for inflammatory disease., European journal of immunology, 2019, Journal Article, PUBLISHED  TARA - Full Text  DOI
Hernandez-Santana YE, Taylor DK, Humbles A, Walsh PT., Advancing the therapeutic potential of the IL-1 family in inflammatory diseases - Meeting report., European journal of immunology, 49, (1), 2019, p8-10 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Schwartz C, Moran T, Saunders S.P, Kaszlikowska A, Floudas A, Bom J, Nunez G, Iwakura Y, O†Neill L, Irvine A.D, McKenzie A.N.J, Ogg G, Walsh P.T, Demengeot J, Fallon P.G, Spontaneous atopic dermatitis in mice with a defective skin barrier is independent of ILC2 and mediated by IL-1β, Allergy: European Journal of Allergy and Clinical Immunology, 2019, p1--, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Mcdonnell, C.J. and Soule, E.E. and Walsh, P.T. and O'donnell, J.S. and Preston, R.J.S., The Immunoregulatory Activities of Activated Protein C in Inflammatory Disease, Seminars in Thrombosis and Hemostasis, 2018, p167 - 175, Journal Article, PUBLISHED  DOI
Boland AJ, Gangadharan N, Kavanagh P, Hemeryck L, Kieran J, Barry M, Walsh PT, Lucitt M., Simvastatin Suppresses Interleukin Iβ Release in Human Peripheral Blood Mononuclear Cells Stimulated With Cholesterol Crystals., J Cardiovasc Pharmacol Ther., 2018, Journal Article, PUBLISHED  DOI

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Patrick Walsh, The role of the IL-1 family of cytokines as mediators of Inflammatory Disease, 2019, TCD and Royal Irish Academy, (1), 49, European Journal of Immunology, 8-10, Meetings /Conferences Organised, PUBLISHED


Award Date
President of Ireland Young Researcher Award SFI 2011-16
Faculty member F1000 Biology 2011
Recipient of GlaxoSmithKline, R&D Exceptional Science Award 2008
Marie Curie Fellow 2009-2013
American Society Of Transplantation Council's Fellowship 2004-2006,
Irish Refining PLC Full University Scholarship, 1997