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Dr. Nigel Stevenson

Associate Professor (Biochemistry)
      
Profile Photo

Dr. Nigel Stevenson

Associate Professor (Biochemistry)

 N.Stevenson@tcd.ie

 3531896 1574


  ANTIVIRAL ACTIVITY   CELL SIGNALLING   HEPATITIS B   HEPATITIS C   HIV   IMMUNOLOGY   Innate immunology   INTERFERON ALPHA
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Zhang Y, Stevenson NJ., MERS-CoV and SARS-CoV-1 proteins inhibit the IFN-" JAK/STAT pathway of epithelial cells, via IFN-lamda-induced USP18., Frontiers in immunology, 17, 2026, p1739662 , Journal Article, PUBLISHED  DOI
Herrera-Uribe, Juber and Convery, Orla and ALmohammadi, Daniah and Weinberg, Fabienne Ingrid and Stevenson, Nigel J., The Neglected Suppressor of Cytokine Signalling (SOCS): SOCS4-7, Inflammation, 2025, Notes: [Cited by: 1], Journal Article, PUBLISHED  DOI
Herrera-Uribe J, Stevenson NJ., SOCS Proteins: Key Players in Immune Regulation During SARS-CoV-2 Infection., European journal of immunology, 55, (8), 2025, pe51645 , Journal Article, PUBLISHED  DOI
Jeremiah, S.S. and Das, P. and Venkatesan, M. and Albinzayed, R. and Ahmed, A. and Stevenson, N.J. and Corbally, M. and Alqahtani, M. and Al-Wedaie, F. and Farid, E. and Hejres, S., Humoral and Innate Immunological Profile of Paediatric Recipients of Pfizer-BioNTech BNT162b2 mRNA Vaccine, Microorganisms, 12, (7), 2024, Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Efstathiou, C. and Zhang, Y. and Kandwal, S. and Fayne, D. and Molloy, E.J. and Stevenson, N.J., Respiratory syncytial virus NS1 inhibits anti-viral Interferon-α-induced JAK/STAT signaling, by limiting the nuclear translocation of STAT1, Frontiers in Immunology, 15, (1395809), 2024, Notes: [cited By 1], Journal Article, PUBLISHED  DOI
Zhang, Y. and Kandwal, S. and Fayne, D. and Stevenson, N.J., MERS-CoV-nsp5 expression in human epithelial BEAS 2b cells attenuates type I interferon production by inhibiting IRF3 nuclear translocation, Cellular and Molecular Life Sciences, 81, (1), 2024, Notes: [Cited by: 5; All Open Access, Hybrid Gold Open Access], Journal Article, PUBLISHED  DOI
Ashraf, M.A. and Mustafa, B.E. and Wahaab, A. and Batool, H. and Ashraf, M. and Said, M.B. and Sevinc, F. and Stevenson, N.J., Conventional and molecular diagnosis of parasites, 2023, 56-72pp, Notes: [cited By 0], Book, PUBLISHED  DOI
Herrera-Uribe J, Naylor P, Rajab E Coskuner G, Jassim MS Jassim, Al-Qahtani M & Stevenson NJ., Long term detection and quantification of SARS-CoV-2 RNA in wastewater in Bahrain., Journal of Hazardous Material Advances, 7, 2022, p1 - 9, p1-9 , Journal Article, PUBLISHED  TARA - Full Text  URL
Zhang, Y. and Gargan, S. and Roche, F.M. and Frieman, M. and Stevenson, N.J., Inhibition of the IFN-α JAK/STAT Pathway by MERS-CoV and SARS-CoV-1 Proteins in Human Epithelial Cells, Viruses, 14, (4), 2022, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
Wahaab, A. and Mustafa, B.E. and Hameed, M. and Stevenson, N.J. and Anwar, M.N. and Liu, K. and Wei, J. and Qiu, Y. and Ma, Z., Potential role of flavivirus ns2b-ns3 proteases in viral pathogenesis and anti-flavivirus drug discovery employing animal cells and models: A review, Viruses, 14, (1), 2022, Notes: [cited By 1], Journal Article, PUBLISHED  TARA - Full Text  DOI
  

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Kelly A, Fahey R, Keogh C, Stevenson NJ, CarrollA , Siddachari R, Geoghegan J, Hegarty JE, Ryan EJ, O'Farrelly C, Cd141+ (bdca-3+) interferon lambda (ifn-λ)-producing dendritic cells are depleted in hepatitis C virus-infected liver, Immunology, 2011, 135, 2011, pp111 , Conference Paper, PUBLISHED
Stevenson NJ, Ryan EJ, Keogh CA, Lloyd AT, Cormican P, Hegarty JE, O'Farrelly C. , Hepatitis C virus (HCV) regulates signal transducer and activator of transcription (STAT) protein expression to escape interferon-alpha (IFN-alpha) responses. , Immunology, 125, (1), 2008, pp71 , Conference Paper, PUBLISHED
Armstrong MA, McClurg AE, Stevenson NJ, Hawkins SA, Johnston JA. , Timing of exposure to interferon beta can alter conventional dendritic cell precursor cell differentiation by upregulating IKBzeta and downregulating NFkB2/p52. , Immunology, 120, (1), 2007, pp36 , Conference Paper, PUBLISHED
Stevenson NJ, Addely M, Greaves D, Johnston J. , Chemokines regulate innate immunity and chemotaxis through Suppressor Of Cytokine Signalling (SOCS) proteins., Clinical Immunology, 2006, ppS127 , Conference Paper, PUBLISHED
Stevenson NJ, Haan S, McClurg A, Armstrong MA, Heinrich P, Johnston JA. , The chemoattractants IL-8 and fMLP regulate G-CSF signalling by inducing suppressor of cytokine signalling (SOCS)-1 expression., Immunology, 116, (1), 2005, pp73 , Conference Paper, PUBLISHED
Stevenson NJ, Haan S, McClurg AE, McGrattan MJ, Armstrong MA, Heinrich PC, JA Johnston, The Chemoattractants, IL-8 and Formyl-Methionyl-Leucyl-Phenylalanine, Regulate Granulocyte Colony-Stimulating Factor Signaling by Inducing Suppressor of Cytokine, Journal of Immunology, 173, (5), 2004, pp3243 - 3249, Conference Paper, PUBLISHED