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Dr. John Southern

Assistant Professor (Chemistry)

Details Date
Reviewer of Dublin City University's Periodic Programme Review - a review of the BSc in Chemical and Pharmacuetical Sciences. 2020
Details Date From Date To
Chartered Chemist and Member of the Royal Society of Chemistry
Mashael A. Alqasem,a Claire Fergus,a J. Mike Southern, *b Stephen J. Connon *b and Vincent P. Kelly, The eukaryotic tRNA-guanine transglycosylase enzyme inserts queuine into tRNA via a sequential bi-bi mechanism, Chemical communications, 56, 2020, p3915 - 3918, Journal Article, PUBLISHED  URL
Mangan D., Mcnabola N., Clark E.H., Bermudez I., Wonnacott S., Southern J.M., Ethyl-for-methyl substitution enhances the subtype specificity of mecamylamine analogues, Organic and Biomolecular Chemistry, 17, (46), 2019, p9892 - 9905, Journal Article, PUBLISHED  DOI
Varghese S, Cotter M, Chevot F, Fergus C, Cunningham C, Mills KH, Connon SJ, Southern JM, Kelly VP. , In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis, Nucleic Acid Research, 45, (4), 2017, p2029 - 2039, Journal Article, PUBLISHED  URL
David Mangan, Neasa McNabola, Emily H. Clark, Isabel Bermudez, Susan Wonnacott and J. Mike Southern, A new synthesis and preliminary evaluation of some analogues of mecamylamine - a compound with anti-addiction properties, Organic and Biomolecular Chemistry, 14, 2016, p10787 - 10798, Journal Article, PUBLISHED  URL
S.J. Connon and J.M. Southern, 'Substituted Pyrimidine Derivatives useful in the Treatment of Autoimmune Diseases', Rouse, WO2016050804 (A1), 2016, Patent, SUBMITTED  URL
Neasa McNabola, Cornelius J. O'Connor, Mark D. Roydhouse, Michael D. Wall, J. Mike Southern, A one-pot synthesis of 3-nitrothiophene and 3-nitro-2-substituted thiophenes, Tetrahedron, 71, (28), 2015, p4598 - 4603, Journal Article, PUBLISHED  URL
Introduction to Aromatic Chemistry in, editor(s)Chris Rostron Jill Barber , Pharmaceutical Chemistry (Integrated Foundations of Pharmacy), Oxford University Press, 2013, [Mike Southern], Book Chapter, PUBLISHED
Michael Southern and David Mangan, 'Derivatives of mecamylamine', Tomkins, 2013, Patent, SUBMITTED  URL
O'Connor, CJ, Roydhouse, MD, Przybyl, AM, Wall, MD, Southern, JM, Facile Synthesis of 3-Nitro-2-substituted Thiophenes, JOURNAL OF ORGANIC CHEMISTRY, 75, (8), 2010, p2534-2538 , Journal Article, PUBLISHED  DOI
Southern, J. Mike; O'Neil, Ian A.; Kearns, Peter, A concise synthesis of highly functionalised 4-thiosugar derivatives, Synlett, 14, 2008, p2158 - 2160, Journal Article, PUBLISHED

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J.M. Southern, Commercialisation of research, 1st year medicinal chemistry external lecture series, DIT, 2019, Invited Talk, PUBLISHED


Award Date
Visiting Professor, Louvain-la-Neuve University, Belgium Jan-Apr 2006