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Dr. Silvin Knight

Senior Research Fellow (Medical Gerontology)

 SILVIN.KNIGHT@tcd.ie

 


Biography

Dr. Silvin Knight currently works as a Senior Research Fellow within the FRAILMatics research programme and The Irish Longitudinal Study on Ageing (TILDA), TCD. His current research interests include quantitative modelling of haemodynamics and autoregulation (measured using Near-infrared Spectroscopy (NIRS), Finometer, and Arterial Spin Labelling (ASL) MRI), as well as developing data-driven and machine learning approaches for the analysis of these neurocardiovascular networks. Prior to joining TILDA, Silvin's research was largely focused on developing model systems and methodologies for improving / characterising the accuracy and precision of a number of quantitative MRI and ultrasound imaging techniques. Silvin completed his PhD at Trinity College Dublin in 2018 (funded by a four year research scholarship from the Irish Cancer Society), which was focused on improving the sensitivity and specificity of dynamic contrast enhanced (DCE) MRI for the detection of prostate cancer. He received his BSc in Physics (with Medical Physics and Bioengineering) from Dublin Institute of Technology in 2013, graduating with first-class honours. Prior to the career change into physics / biomedical engineering in 2010, he worked for over 10 years in the design / advertising industry as a graphic designer / project manager.

Representations

Details Date
Associate Editor for The IEEE Journal of Translational Engineering in Health and Medicine (JTEHM) 1/1/2022
A., Shirsath M., O'Connor J.D., Boyle R., Newman L., Knight S.P., Hernandez B., Whelan R., Meaney J.F., Kenny R.A., Slower speed of blood pressure recovery after standing is associated with accelerated brain aging: Evidence from The Irish Longitudinal Study on Ageing (TILDA), Cerebral Circulation - Cognition and Behavior, 6, 2024, Journal Article, PUBLISHED  DOI  DOI
Feng Xue, Silvin P. Knight, Emma Connolly, Aisling M. O"Halloran, Morgana Afonso Shirsath, Louise Newman, Eoin Duggan, Rose Anne Kenny, Roman Romero-Ortuno, Were Frailty Identification Criteria Created Equal? A Comparative Case Study on Continuous Non-Invasively Collected Neurocardiovascular Signals during an Active Standing Test in the Irish Longitudinal Study on Ageing (TILDA), Sensors, 2024, Journal Article, IN_PRESS  TARA - Full Text  DOI  URL
Simon C, Bolton DAE, Meaney JF, Kenny RA, Simon VA, De Looze C, Knight S, Ruddy KL., White matter fibre density in the brain's inhibitory control network is associated with falling in low activity older adults., The European journal of neuroscience, 2024, Journal Article, PUBLISHED  DOI
De Looze C, Demnitz N, Knight S, Carey D, Meaney J, Kenny RA, McCrory C., Examining the impact of socio-economic position (SEP) across the life course on cognitive function and brain structure in healthy ageing., The journals of gerontology. Series A, Biological sciences and medical sciences, 2023, pglad068 , Journal Article, PUBLISHED  DOI
Knight SP, Ward M, Duggan E, Xue F, Kenny RA, Romero-Ortuno R., Evaluation of a 3-Item Health Index in Predicting Mortality Risk: A 12-Year Follow-Up Study, Diagnostics, 2023, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Gutiérrez-Zúñiga R, Davis J.R., Boyle R, De Looze C, Meaney J, Whelan R, Kenny R.A., Knight S.P., Romero-Ortuño R, Brain connectivity in frailty: insights from The Irish Longitudinal Study on Ageing (TILDA), Neurobiology of Aging, 2023, Journal Article, PUBLISHED  DOI  URL
Doran S, Carey D, Knight S, Meaney JF, Kenny RA, De Looze C., Relationship between hippocampal subfield volumes and cognitive decline in healthy subjects., Frontiers in aging neuroscience, 15, 2023, p1284619 , Journal Article, PUBLISHED  DOI
Gutiérrez-Zúñiga R, Davis J.R., Ruddy K, De Looze C, Carey D, Meaney J, Kenny R.A., Knight S.P. and Romero-Ortuno R, Structural brain signatures of frailty, defined as accumulation of self-reported health deficits in older adults, Frontiers in Aging Neuroscience, 2023, Journal Article, PUBLISHED  DOI  URL
Eoin Duggan, Silvin P. Knight, Roman Romero-Ortuno, Relationship Between Sarcopenia and Orthostatic Blood Pressure Recovery in Older Falls Clinic Attendees, European Geriatric Medicine, 2023, Journal Article, PUBLISHED  TARA - Full Text  DOI
Silvin P. Knight, "Dancing with Atoms": A tribute to Sheila Tinney, Leonardo, 56, (6), 2023, p592-597 , Journal Article, PUBLISHED  DOI  URL
  

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