Skip to main content

Trinity College Dublin, The University of Dublin

Menu Search


Trinity College Dublin By using this website you consent to the use of cookies in accordance with the Trinity cookie policy. For more information on cookies see our cookie policy.

      
Profile Photo

Dr. Mary O'Sullivan

Research Fellow (Clinical Medicine)
Associate Research Lecturer (Trinity Translational Medicine Institute)
      
Profile Photo

Dr. Mary O'Sullivan

Research Fellow (Clinical Medicine)

 Mary.OSullivan@tcd.ie

 3531896 4296

Associate Research Lecturer (Trinity Translational Medicine Institute)


  Apoptosis   Autophagy   Caspase proteases   CELL DEATH   Host, Pathogen interactions   Imaging Techniques   Immunology   Infectious diseases   Inflammation   Innate immunology   Intra and intercellular signalling   Metabolism   Mycobacterium tuberculosis
Project Title
 Investigation of the fungicidal activity of macrophages against the fungal pathogen Aspergillus fumigatus with an automated live cell imaging microscope.
From
To
Summary
Funding Agency
TTMI BEHR funding
Project Title
 Investigation of the fungicidal activity of macrophages against the fungal pathogen Aspergillus fumigatus with an automated live cell imaging microscope.
From
To
Summary
Funding Agency
Trinity Translational Medicine Institute Bursary
Project Title
 Correcting Pulmonary Immunity through manipulation of CFTR
From
2021
To
2023
Summary
Funding Agency
HRCI/HRB
Programme
HRCI/HRB Joint Funding Scheme 2020
Project Title
 Defining the role of human dendritic cell subsets in host immune responses to mycobacterial infection.
From
2013
To
31-12-2017
Summary
Funding Agency
HRB
Programme
HRA
Person Months
36
Project Title
 Immunometabolic manipulation of pulmonary immunity - towards TB host directed therapy
From
2019
To
Summary
Funding Agency
HRB
Programme
ILP

Page 1 of 2
Details Date
Member, Imaging Focus Group Meeting, 1-Day meeting on Biomedical Imaging - 8th June 2004 run in conjunction with TCINFrom single cell & molecular through to organ & whole bodyLast Revised : 22 May 2004
Member, PHG Funded PI's and Researchers, All Researchers funded under Cycle 3 PRTLI - Programme for Human Genomics
Details Date From Date To
American Association for the Advancement of Science 1995 Present
American Thoracic Society 2009
Conor Grant, Emily Duffin, Finbarr O'Connell, Parthiban Nadarajan, Colm Bergin, Joseph Keane, Mary P. O'Sullivan, Human Alveolar Macrophages Detect SARS-CoV-2 Envelope Protein Through TLR2 and TLR4 and Secrete Cytokines in Response, Immunology, 2025, Journal Article, PUBLISHED  DOI
Thong L, Sandby Thomas O, Ó Gallchobhair O, Duffin E, Yennemadi AS, Leisching G, Murphy DM, Nadarajan P, O'Connell F, O'Sullivan MP, Basdeo SA, Cox DJ, Keane J., Dexamethasone inhibits Mycobacterium tuberculosis-induced glycolysis but preserves antimicrobial function in primary human macrophages., Scientific Reports, 15, (1), 2025, p34310 , Journal Article, PUBLISHED  DOI
Brown K, Walsh A, Yennemadi A, O'Leary S, O'Sullivan M, Nadarajan P, Basdeo S, Leisching G, Keane J, Mycobacterium tuberculosis Induces Warburg Metabolism in Human Alveolar Macrophages: A Transcriptomic Analysis., American Journal of Respiratory Cell and Molecular Biology, 2025, Journal Article, PUBLISHED  DOI
Brown K, Walsh A, Yennemadi A, O'Leary S, O'Sullivan M, Nadarajan P, Basdeo S, Leisching G, Keane J, <i>Mycobacterium tuberculosis</i> Induces Warburg Metabolism in Human Alveolar Macrophages: A Transcriptomic Analysis., American journal of respiratory cell and molecular biology, 2025, Journal Article, PUBLISHED  DOI
Conor Grant, Colm Bergin, Joseph Keane, Mary P. O'Sullivan, All Trans Retinoic Acid as a Host-directed Therapy for Nontuberculous Mycobacteria, American Thoracic Society, 2024, ppA6273-, Conference Paper, PUBLISHED  DOI
Bahlool AZ, Cavanagh B, Sullivan AO, MacLoughlin R, Keane J, O'Sullivan MP, Cryan SA., Microfluidics produced ATRA-loaded PLGA NPs reduced tuberculosis burden in alveolar epithelial cells and enabled high delivered dose under simulated human breathing pattern in 3D printed head models., European Journal of Pharmaceutical Sciences : official journal of the European Federation for Pharmaceutical Sciences, 2024, p106734 , Journal Article, PUBLISHED  DOI
Triglia D, Gogan KM, Keane J, O'Sullivan MP., Glucose metabolism and its role in the maturation and migration of human CD1c+ dendritic cells following exposure to BCG., Frontiers in Cellular and Infection Microbiology, 13, 2023, p1113744 , Journal Article, PUBLISHED  DOI
Bedard M, van der Niet S, Bernard EM, Babunovic GH, Cheng TY, Aylan B, Grootemaat AE, Raman S, Botella L, Ishikawa E, O'Sullivan MP, O'Leary S, Mayfield JA, Buter J, Minnaard AJ, Fortune SM, Murphy LO, Ory DS, Keane J, Yamasaki S, Gutierrez MG, van der Wel N, Moody DB., A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages., The Journal of Clinical Investigation, 133, (6), 2023, pe161944 , Journal Article, PUBLISHED  DOI
Bahlool AZ, Grant C, Cryan SA, Keane J, O'Sullivan MP., All trans retinoic acid as a host-directed immunotherapy for tuberculosis., Curr Res Immunol, 3, 2022, p54-72 , Journal Article, PUBLISHED  DOI
Bahlool AZ, Fattah S, O'Sullivan A, Cavanagh B, MacLoughlin R, Keane J, O'Sullivan MP, Cryan SA., Development of Inhalable ATRA-Loaded PLGA Nanoparticles as Host-Directed Immunotherapy against Tuberculosis., Pharmaceutics, 14, (8), 2022, p1745 , Journal Article, PUBLISHED  DOI
  

Page 1 of 5
Regulation of epithelial-leukocyte interaction and epithelial immune-response genes in, Asthma and Rhinitis, Cambridge, MA, Blackwell Scientific, 2000, pp784 - 800, [MJ Holtzman, M Castro, DC Look, M O'Sullivan, MJ Walter], Book Chapter, PUBLISHED

  


Award Date
Dean's Research Initiatives Research Fund Bursary February 2016
American Thoracic Society Travel Award 2007
Irish Thoracic Society Award for Best Oral Presentation 2008