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Dr. Norita Gildea

Assistant Professor (Physiology)
      
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Dr. Norita Gildea

Assistant Professor (Physiology)

 ngildea@tcd.ie

 


Dr Norita Gildea obtained her PhD in Exercise Physiology in 2017 from Trinity College Dublin. Her doctoral research was centered on exercise intolerance and microvascular dysfunction in individuals with type 2 diabetes. Her research interests extend to understanding the cellular mechanisms that influence macro- and microvascular function within prediabetes and ageing and the effect of different exercise training and lifestyle interventions on vascular and metabolic adaptations therein. Her work is focused on how personalised exercise prescription and other novel therapeutic interventions can improve both glycaemic and blood pressure control and reduce cardiovascular and cerebrovascular risk factors that are central to reducing the burden of prediabetes, and its progression to overt type 2 diabetes, in a plight for successful ageing.
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E. Curtin, M.E. Weston, P. Buys, T. Bissoonauth, H. Al-Shammary, O. Ojelabi, A. Osman, J. Li, T. Wickramasinghe, Y. Lim, Z. Ching, M. Carey, E. Rooney, M. Egaña, N. Gildea, The effects of sex and fitness on cerebrovascular reactivity and cerebral autoregulation in healthy young adults., Proc Physiol Soc, Physiology in Focus 2024, Newcastle UK, July 2024, 2024, Conference Paper, PUBLISHED
P. Buys, E. Curtin, C. Brady, C. Rooney, A. Alshahrabally, P. McConkey, S. Donohoe, H. Darwish, S. Spring, G. Hagon, C. Gallagher, A. Mahon, N. Gildea, M. Egaña, M.E. Weston., The acute effect of maximal sprint exercise on cerebrovascular reactivity in healthy young adults, Proc Physiol Soc, Physiology in Focus 2024, Newcastle UK, July 2024, 2024, Conference Paper, PUBLISHED
M.E. Weston, P. Buys, E. Curtin, D. Guichard, E. Harbison, A. Croce, E. Ng, C. Delle Monache, A. Maero, G. Tan Tan, T. Khoo, A. Sreekanth, N. Gildea, M. Egaña, Dynamic cerebral autoregulation is unchanged following maximal sprint exercise in healthy young adults, Proc Physiol Soc, Physiology in Focus 2024, Newcastle UK, July 2024, 2024, Conference Paper, PUBLISHED
McDermott A, Nevin A, Gildea N, Rocha J, O'Shea D, Egaña M., Muscle deoxygenation during ramp incremental cycle exercise in older adults with type 2 diabetes., European Journal of Applied Physiology, Feb, (124(2)), 2024, p561 - 571, Notes: [doi: 10.1007/s00421-023-05297-y], Journal Article, PUBLISHED  URL
Gildea N, McDermott A, Rocha J, Nevin A, O'Shea D, Green S & Egaña M, Influence of HIIT and MICT on the effects of "priming" exercise on oxygen uptake kinetics during moderate-intensity exercise in individuals with type 2 diabetes, Proc Physiol Soc., Europhysiology , Copenhagen, Denmark, September, 2022, Conference Paper, PUBLISHED
Gildea N, McDermott A, Rocha J, Crognale D, Nevin A, O'Shea D, Green S & Egaña M , Low-volume HIIT and MICT speed VO2 kinetics during high-intensity "work-to-work" cycling with a similar time-course in type 2 diabetes., J Appl Physiol, (133), 2022, p273 - 287, Journal Article, PUBLISHED  TARA - Full Text
Green S, Kiely C, O'Connor E, Gildea N, O'Shea D & Egaña M, Differential effects of sex on adaptive responses of skeletal muscle vasodilation to exercise training in type 2 diabetes., J Diabetes Complications, (36), 2022, Journal Article, PUBLISHED
Rocha J, Gildea N, O'Shea D, Green S, Egaña M, Priming exercise accelerates oxygen uptake kinetics during high-intensity cycle exercise in middle-aged individuals with type 2 diabetes., Frontiers in Physiology, 18, (13), 2022, Journal Article, PUBLISHED
Egaña M, Allen L, Gleeson K, Gildea N & Warmington S, Post-exercise cold water immersion does not improve subsequent 4-km cycling time-trial compared with passive and active recovery in normothermia, Front Sports Act Living, (25), 2021, Journal Article, PUBLISHED
Gildea N, McDermott A, Rocha J, Green S, O'Shea D & Egaña M, Time-course of VO2 kinetics responses during moderate-intensity exercise subsequent to HIIT versus moderate-intensity continuous training in type 2 diabetes, J Appl Physiol , (130), 2021, p1646 - 1659, Journal Article, PUBLISHED
  

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Dr. Gildea's research interests in type 2 diabetes also extend to understanding the cellular mechanisms that influence macro- and microvascular function within prediabetes and ageing and the effect of different exercise training and lifestyle interventions on vascular and metabolic adaptations therein. Her work is focused on how personalised exercise prescription and other novel therapeutic interventions can improve both glycaemic and blood pressure control and reduce modifiable cardiovascular and cerebrovascular risk factors that are central to reducing the burden of prediabetes, and its progression to overt type 2 diabetes, in a plight for healthy ageing. Given the increased propensity for the development of cerebrovascular disease in both type 2 diabetes and prediabetes, therapeutic interventions to either, help restore decreased cerebrovascular function, or ameliorate further deficits leading to potential cognitive decline are paramount in these burgeoning populations. Dr. Gildea hopes to bolster current efforts to advance translational science and global health by addressing the dose-response relationship of exercise on cerebrovascular health in accordance with disease and population specificity. Ultimately serving to delay potential stroke, cognitive decline and/or dementia in those living with type 2 diabetes or prediabetes, and subsequently bestow corresponding benefits upon patient's families, the healthcare system, and society in general.