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Professor Michael Rowan

Fellow Emeritus (Pharmacology & Therapeutics)

 

Fellow Emeritus (Trinity Inst. of Neurosciences (TCIN))


 Mechanisms of the synaptic plasticity disrupting actions of Aß
  Neurocardiovascular influences on cognitive functioning
 MEMOLOAD

Ondrejcak T, Klyubin I, Hu NW, Yang Y, Zhang Q, Rodriguez BJ and Rowan MJ, Rapidly reversible persistent long-term potentiation inhibition by patient-derived brain tau and amyloid ß proteins, Philosophical Transactions of the Royal Society B, (379), 2024, p20230234 , Journal Article, IN_PRESS  DOI
Neng-Wei Hu, Tomas Ondrejcak, Igor Klyubin, Yin Yang, Dominic M. Walsh, Frederick J. Livesey, and Michael J. Rowan, Patient-derived tau and amyloid-ß facilitate long-term depression in vivo: role of tumor necrosis factor alpha and the integrated stress response, Brain Communications, 2024, p10.1093/braincomms/fcae333 , Journal Article, ACCEPTED  TARA - Full Text  DOI
Hu Z, Ondrejcak T, Yu P, Zhang Y, Yang Y, Klyubin I, Rowan MJ, Kennelly SP, Hu NW, Do tau-synaptic long-term depression interactions in the hippocampus play a pivotal role in the progression of Alzheimer's disease?, Neural Regeneration Research, 18, (6), 2023, p1213-1219 , Journal Article, PUBLISHED  DOI
Ondrejcak T, Klyubin I, Hu NW, O'Malley TT, Corbett GT, Winters R, Perkinton MS, Billinton A, Prenderville JA, Walsh DM, Rowan MJ, Tau and amyloid ß protein in patient-derived aqueous brain extracts act concomitantly to disrupt LTP in vivo, The Journal of Neuroscience, 43, (32), 2023, p5870--5879 , Journal Article, PUBLISHED  DOI
Yin Yang, Tomas Ondrejcak, Neng-Wei Hu, Sadia Islam, Eugene O'Rourke, Richard Reilly, Colm Cunningham, Michael Rowan, Igor Klyubin, Gamma-patterned sensory stimulation reverses synaptic plasticity deficits in rat models of early Alzheimer's disease, European Journal of Neuroscience, 58, (6), 2023, p3402 - 3411, Journal Article, PUBLISHED  DOI
Hu Z, Yu P, Zhang Y, Yang Y, Zhu M, Qin S, Xu JT, Duan D, Wu Y, Wang D, Rowan MJ and Hu NW, Inhibition of the ISR abrogates mGluR5-dependent long-term depression and spatial memory deficits in a rat model of Alzheimer's disease, Translational Psychiatry, 12, (1), 2022, Journal Article, PUBLISHED  DOI
Zhang Y, Yang Y, Hu Z, Zhu M, Qin S, Yu P, Li B, Xu J, Ondrejcak T, Klyubin I and Rowan MJ, Hu NW, Long-term depression-inducing low frequency stimulation enhances p-Tau181 and p-Tau217 in an age-dependent manner in live rats, Journal of Alzheimer's Disease, 89, (1), 2022, p335--350 , Journal Article, PUBLISHED  DOI
Klyubin I, Ondrejcak T, Hu NW, Rowan MJ, Glucocorticoids, synaptic plasticity and Alzheimer's disease, Current Opinion in Endocrine and Metabolic Research, 25, 2022, p100365 , Journal Article, PUBLISHED  DOI
Qi Y, Klyubin I, Ondrejcak T, Hu NW, Rowan Mj, Enduring glucocorticoid-evoked exacerbation of synaptic plasticity disruption in male rats modelling early Alzheimer's disease amyloidosis, Neuropsychopharmacology, 46, (12), 2021, p2170 - 2179, Journal Article, PUBLISHED  DOI
Sosulina, L. and Mittag, M. and Geis, H.-R. and Hoffmann, K. and Klyubin, I. and Qi, Y. and Steffen, J. and Friedrichs, D. and Henneberg, N. and Fuhrmann, F. and Justus, D. and Keppler, K. and Cuello, A.C. and Rowan, M.J. and Fuhrmann, M. and Remy, S., Hippocampal hyperactivity in a rat model of Alzheimer†s disease, Journal of Neurochemistry, 157, (6), 2021, p2128-2144 , Notes: [cited By 5], Journal Article, PUBLISHED  DOI
  

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