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Dr. Barry Moran

Experimental Officer (Biochemistry)

Details Date From Date To
International Society for Advancement of Cytometry
Royal Microscopical Society
Irish Society for Immunology
British Society for Immunology
Cytometry Society of Ireland
Borkner L, Curham LM, Wilk MM, Moran B, Mills KHG., IL-17 mediates protective immunity against nasal infection with Bordetella pertussis by mobilizing neutrophils, especially Siglec-F+ neutrophils., Mucosal immunology, 2021, Journal Article, PUBLISHED  TARA - Full Text  DOI
Anindya Mukhopadhya, Jessie Santoro, Barry Moran, Zivile Useckaite, Lorraine O'Driscoll , Optimisation and comparison of orthogonal methods for separation and characterisation of extracellular vesicles to investigate how representative infant milk formula is of milk, Food Chemistry, 353, 2021, p129309-, Journal Article, PUBLISHED  DOI  URL
Fletcher JM, Moran B, Petrasca A, Smith CM., IL-17 in inflammatory skin diseases psoriasis and hidradenitis suppurativa., Clinical and experimental immunology, 201, (2), 2020, p121-134 , Journal Article, PUBLISHED  DOI
Edwards, S.C. and Sutton, C.E. and Ladell, K. and Grant, E.J. and McLaren, J.E. and Roche, F. and Dash, P. and Apiwattanakul, N. and Awad, W. and Miners, K.L. and Lalor, S.J. and Ribot, J.C. and Baik, S. and Moran, B. and McGinley, A. and Pivorunas, V. and Dowding, L. and Macoritto, M. and Paez-Cortez, J. and Slavin, A. and Anderson, G. and Silva-Santos, B. and Hokamp, K. and Price, D.A. and Thomas, P.G. and McLoughlin, R.M. and Mills, K.H.G., A population of proinflammatory T cells coexpresses αβ and γΎ T cell receptors in mice and humans, Journal of Experimental Medicine, 217, (5), 2020, Notes: [cited By 1], Journal Article, PUBLISHED  TARA - Full Text  DOI
Lecordier L, Uzureau S, Vanwalleghem G, Deleu M, Crowet JM, Barry P, Moran B, Voorheis P, Dumitru AC, Yamaryo-Botté Y, Dieu M, Tebabi P, Vanhollebeke B, Lins L, Botté CY, Alsteens D, Dufrêne Y, Pérez-Morga D, Nolan DP, Pays E., The Trypanosoma Brucei KIFC1 Kinesin Ensures the Fast Antibody Clearance Required for Parasite Infectivity., iScience, 23, (9), 2020, p101476 , Journal Article, PUBLISHED  DOI
Useckaite Z, Mukhopadhya A, Moran B, O'Driscoll L., Extracellular vesicles report on the MET status of their cells of origin regardless of the method used for their isolation., Scientific reports, 10, (1), 2020, p19020 , Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Sulaimani J, Cluxton D, Clowry J, Petrasca A, Molloy OE, Moran B, Sweeney CM, Malara A, McNicholas N, McGuigan C, Kirby B, Fletcher JM., Dimethyl fumarate modulates the Treg-Th17 cell axis in patients with psoriasis., The British journal of dermatology, 2020, Journal Article, PUBLISHED  DOI
Floudas A, Neto N, Marzaioli V, Murray K, Moran B, Monaghan MG, Low C, Mullan RH, Rao N, Krishna V, Nagpal S, Veale DJ, Fearon U., Pathogenic, glycolytic PD-1+ B cells accumulate in the hypoxic RA joint., JCI insight, 5, (21), 2020, Journal Article, PUBLISHED  DOI
Moran B, Gallagher C, Tobin AM, Fletcher JM., Enrichment of polyfunctional IL-17 producing T cells in paradoxical psoriasis skin lesions., The Journal of investigative dermatology, 2019, Journal Article, PUBLISHED  DOI
Cluxton D, Petrasca A, Moran B, Fletcher JM, Differential regulation of human Treg and Th17 cells by fatty acid synthesis and glycolysis, Frontiers in Immunology, 10, 2019, p115-, Journal Article, PUBLISHED  TARA - Full Text  DOI

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Dr Barry Moran runs the Flow Cytometry Facility, within the Trinity Biomedical Sciences Institute. Flow cytometry is a complex technology used to interrogate the phenotype and function of cells in many areas of life science and biomedical research, including immunology and cancer. It involves sensitive, precision-based cellular analysis of multiple parameters on individual cells at incredibly high speeds. Millions of data points can be generated per second, requiring sophisticated analysis tools. Key infrastructure within TBSI's Flow Cytometry Facility include high-end platforms (high-speed cell sorter, imaging cytometer, high-dimensional spectral analyser) and four advanced cytometer analysers. Dr Moran has a particular interest in immune dysfunction in the skin, primarily in the disease hidradenitis suppurativa.