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Dr. Rachel Mary Mc Loughlin

Professor in Immunology (Biochemistry)

 Skin delivery and tissue-resident T cell responses: implications for innovative vaccines
 Characterisation and exploitation of skin resident memory CD4 T cells for novel vaccines for Staphylococcus aureus
 Vaccination:Knowledge is Power
 Delineating immune memory to Staphylococcus aureus
 Staphylococcus aureus induced immunosuppressive memory: consequences for bug and for host

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Details Date
Member of the Welcome Immune System in Health and Disease Expert Review Group 2020
Associate editor PLOS Pathogens. 2020
Editorial board member Infection and Immunity 2019
Details Date From Date To
International Cytokine Society 2002 to date
British Society Immunology 2010 to date
American Association of Immunology 2005 2013
Infectious Diseases Society of America 2006-2009
American Association of Microbiology 2011 to date
Clowry Juliann, Dempsey Daniel J, Claxton Tracey J, Towell Aisling M, Turley Mary B, Sutton Marti, Geoghegan Joan A, Kezic Sanj, Jakasa Ivon, White Arthu, Irvine Alan D, McLoughlin Rachel M, Distinct T cell signatures are associated with Staphylococcus aureus skin infection in pediatric atopic dermatitis, 9, (9), 2024, p1-19 , Journal Article, PUBLISHED  DOI  URL
Mannion JM, McLoughlin RM, Lalor SJ, The Airway Microbiome-IL-17 Axis: a Critical Regulator of Chronic Inflammatory Disease, Clinical Reviews in Allergy & Immunology,, March 11, 2022, Journal Article, PUBLISHED  DOI
Townsend L, Dyer AH, Naughton A, Imangaliyev S, Dunne J, Kiersey R, Holden D, Mooney A, Leavy D, Ridge K, Sugrue J, Aldoseri M, Kelliher JH, NĂ­ Cheallaigh C, Severe COVID-19 is characterised by inflammation and immature myeloid cells early in disease progression, Heliyon, 8, (4), 2022, pe09230 - e09236, Journal Article, PUBLISHED
Cooper AJR, Clegg J, Cassidy FC, Hogan AE, McLoughlin RM., Human MAIT Cells Respond to Staphylococcus aureus with Enhanced Anti-Bacterial Activity., Microorganisms, 10, (1), 2022, Journal Article, PUBLISHED  DOI
Megan B. O"Brien, Charlotte L. Beynon, Rachel M. McLoughlin, Kieran G. Meade, The immune response in bovine primary dermal fibroblasts is influenced by Interleukin 8 promoter haplotype and vitamin D, Veterinary Immunology and Immunopathology, 238, 2021, p110291 , Journal Article, PUBLISHED
Clegg J, Soldaini E, McLoughlin RM, Rittenhouse S, Bagnoli F, Phogat S, Staphylococcus aureus Vaccine Research and Development: The Past, Present and Future, Including Novel Therapeutic Strategies., Frontiers in immunology, 2021, Journal Article, PUBLISHED
Douglas E, Brignoli T, Recker M, O"Brien E, McLoughlin RM, Massey RC, Self-sensitisation of Staphylococcus aureus to the antimicrobial factors found in human blood, 2021, Journal Article, PUBLISHED
O'Brien MB, McLoughlin RM, Roche C, Nelson CD, Meade KG, Effect of IL-8 haplotype on temporal profile in circulating concentrations of interleukin 8 and 25(OH) vitamin D in Holstein-Friesian calves., Veterinary immunology and immunopathology, 2021, Journal Article, PUBLISHED
Vozza EG, Mulcahy ME, McLoughlin RM, Making the Most of the Host; Targeting the Autophagy Pathway Facilitates Staphylococcus aureus Intracellular Survival in Neutrophils., Frontiers in immunology, 2021, Journal Article, PUBLISHED
Fox PG, Schiavetti F, Rappuoli R, McLoughlin RM, Bagnoli F, Staphylococcal Protein A Induces Leukocyte Necrosis by Complexing with Human Immunoglobulins., mBio, 2021, Journal Article, PUBLISHED

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Award Date
Elected to Fellowship Trinity College Dublin 2016