Professor Rustom Manecksha

Summary

Randomized control trial to compare the efficacy and safety of percutaneous nephrostomy with retrograde ureteric stenting for emergency renal decompression in cases of obstruction and sepsis associated with ureteric calculi. The obstructed kidney in the setting of urosepsis is a urological emergency. Stone manipulation in the setting of active, untreated infection with concomitant urinary tract obstruction can lead to life-threatening sepsis. Therefore, urgent decompression of the collecting system is warranted. There are two options for urgent decompression of an obstructed collecting system: Image-guided percutaneous nephrostomy tube placement Cystoscopic retrograde placement of a ureteric stent This strategy allows drainage of infected urine and penetration of antibiotics to the affected renal unit. Definitive stone manipulation should be delayed until the infection is cleared following an appropriate course of antimicrobial therapy. Both the European Association of Urology (EAU) and the American Urological Association (AUA) provide guidelines for management of an obstructed kidney. Both organisations provide evidence-based statements of the highest recommendation that urgent decompression of the kidney is mandated in the setting of sepsis. However, neither organisation recommend one decompression modality over the other. There is a lack of high quality up-to-date evidence to support a consensus view that one method of decompression is superior to the other. This study aims to determine the most effective method of renal decompression in cases of obstruction and sepsis associated with ureteric calculi.

Funding Agency

Self funded

Project Type

RCT

Summary

The Men and Sexual Health Prostate Cancer Study is a joint Cancer Council Queensland and Griffith University Queensland project, led by Professor Suzanne Chambers of Griffith University, and coordinated in Ireland by Mr Rustom Manecksha, Consultant Urological Surgeon at St James's and Tallaght Hospitals. This online study will assess concerns about sexual health and what contributes to a man's decision to seek support for their sexual concerns. Part of the purpose of this study is to allow researchers/clinicians to better understand the needs of men so that they can then devise various programmes and resource their rehabilitation accordingly.

Funding Agency

Cancer Council Queensland

Summary

Prospective study of risk factors that increase the likelihood of damage to reusable flexible ureteroscopes. A collaborative study with The Austin Hospital, Melbourne

Funding Agency

no funding

Project Type

Prospective