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Professor Tríona Lally

Professor in BioEngineering (Mechanical, Manuf & Biomedical Eng)
PARSONS BUILDING

 lallyca@tcd.ie

 3531896 3159


Biography

Dr. Caitríona Lally received her BEng (Mechanical Engineering) and MEng (Biomedical Engineering) degrees from University of Limerick and later obtained a PhD from Trinity College Dublin in the area of arterial biomechanics and cardiovascular stenting. In March 2004 she took up a lecturing position in the School of Mechanical & Manufacturing Engineering at Dublin City University, and was appointed senior lecturer in 2014. In 2015, she joined the Department of Mechanical & Manufacturing Engineering in Trinity College Dublin as a Professor in Bioengineering where she continues to carry out research focused on arterial tissue mechanics, vascular imaging, vascular mechanobiology and tissue engineering. She has secured considerable research funding from SFI, Enterprise Ireland and the IRC and was awarded an ERC starting grant in 2014.

Representations

Details Date
Research Committee Member

Memberships

Membership of Professional Institutions, Associations, Societies

Details Date From Date To
Member of the Institution of Engineers of Ireland (MIEI) and member of the committee for the Biomedical Division of the IEI (2006-2009) Member of the Royal Academy of Medicine of Ireland (RAMI) and the European Society of Biomechanics. PI in the Trinity Centre for Bioengineering
Johnston, Robert D., Ghasemi, Milad, Lally, Caitríona, Inverse material parameter estimation of patient"specific finite element models at the carotid bifurcation: The impact of excluding the zero"pressure configuration and residual stress, International Journal for Numerical Methods in Biomedical Engineering, 39, (1), 2023, Journal Article, PUBLISHED  DOI
Tornifoglio B., Johnston R.D., Stone A.J., Kerskens C., Lally C., Microstructural and mechanical insight into atherosclerotic plaques: an ex vivo DTI study to better assess plaque vulnerability, Biomechanics and Modeling in Mechanobiology, 2023, Journal Article, PUBLISHED  DOI
Tornifoglio B., Stone A.J., Kerskens C., Lally C., Ex Vivo Study Using Diffusion Tensor Imaging to Identify Biomarkers of Atherosclerotic Disease in Human Cadaveric Carotid Arteries, Arteriosclerosis, Thrombosis, and Vascular Biology, 42, (11), 2022, p1398 - 1412, p1398-1412 , Journal Article, PUBLISHED  DOI
Brooke Tornifoglio, Alan J. Stone, Robert D. Johnston, Salmon S. Shahid, Christian Kerskens, Caitriona Lally, Diffusion tensor imaging and arterial tissue: establishing the influence of arterial tissue microstructure on fractional anisotropy, mean diffusivity and tractography, Scientific Reports, 2021, Journal Article, PUBLISHED  TARA - Full Text
Ghasemi M., Nolan D.R., Lally C., Assessment of mechanical indicators of carotid plaque vulnerability: Geometrical curvature metric, plaque stresses and damage in tissue fibres, Journal of the Mechanical Behavior of Biomedical Materials, 103, 2020, Journal Article, PUBLISHED  DOI
Mathieu P.S., Fitzpatrick E., Di Luca M., Cahill P.A., Lally C., Resident multipotent vascular stem cells exhibit amplitude dependent strain avoidance similar to that of vascular smooth muscle cells, Biochemical and Biophysical Research Communications, 521, (3), 2020, p762 - 768, p762-768 , Journal Article, PUBLISHED  DOI
Alix Whelan, Elizabeth Williams, David Nolan, Bruce Murphy, Paul Gunning, David O'Reilly, Caitríona Lally, Bovine pericardium of high fibre dispersion has high fatigue life and increased collagen content; potentially an untapped source of heart valve leaflet tissue , Annals of Biomedical Engineering, 2020, Journal Article, PUBLISHED  TARA - Full Text
Alix Whelan, Collagen fibre orientation and dispersion govern ultimate tensile strength, stiffness and the fatigue performance of bovine pericardium, Journal of the Mechanical Behavior of Biomedical Materials, 90, 2019, p54 - 60, Journal Article, PUBLISHED  TARA - Full Text  DOI
Clarkin O.M., Wu B., Cahill P.A., Brougham D.F., Banerjee D., Brady S.A., Fox E.K., Lally C., Novel injectable gallium-based self-setting glass-alginate hydrogel composite for cardiovascular tissue engineering, Carbohydrate Polymers, 217, 2019, p152 - 159, p152-159 , Journal Article, PUBLISHED  DOI
Schipani, R. and Nolan, D.R. and Lally, C. and Kelly, D.J., Integrating finite element modelling and 3D printing to engineer biomimetic polymeric scaffolds for tissue engineering, Connective Tissue Research, 2019, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
  

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Robert Gaul, Caitriona Lally, Strain mediated enzyme degradation of arterial tissue characterised by small angle light scattering, Proceedings of the 23rd Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland., Belfast, Ireland, 2017, Oral Presentation, PRESENTED
Alix Whelan, Robert Gaul, Paul Gunning, Caitriona Lally, Investigation of Collagen Fibre Orientation in Bovine Pericardium, Proceedings of the 23rd Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, Belfast, 20/01/17, 2017, Oral Presentation, PRESENTED
Robert Gaul, Caitriona Lally, Load induced changes in collagen fibre architecture in arteries characterised by small angle light scattering, Proceedings of the 22nd Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, Galway, Ireland, 2016, Oral Presentation, PRESENTED
Robert Gaul, Caitriona Lally, The use of small angle light scattering for the characterisation of collagen fibre orientation in arteries, Proceedings of the 21st Annual Conference of the Section of Bioengineering of the Royal Academy of Medicine in Ireland, Kildare, Ireland, 2015, Oral Presentation, PRESENTED
Simulation of in-stent restenosis for the design of cardiovascular stents in, G. Holzpafel & R. Ogden , Mechanics of Biological Tissue, Springer, 2006, pp255 - 267, [Lally, C, Prendergast, PJ], Book Chapter, PUBLISHED

  

Awards and Honours

Award Date
ERC Starting Grant 2014
Senior author on research paper which was awarded 2nd prize for the Engineers Ireland - IMECHE Young Engineers Research Award 2012
Career Start Grant (DCU) 2005
Royal Society of Medicine in Ireland, 1st prize for best student paper 2004
Royal Society of Medicine in Ireland, 2nd prize for best student paper 2002
Bernard Crossland Symposium, 2nd prize for best student paper 2002
Sylvestor O'Halloran Surgical Meeting, 1st prize in poster presentation 2002