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Dr. Igor Klyubin

Senior Research Fellow (Pharmacology & Therapeutics)

An K, Klyubin I, Kim Y, Jung JH, Mably AJ, O'Dowd ST, Lynch T, Kanmert D, Lemere CA, Finan GM, Park JW, Kim TW, Walsh DM, Rowan MJ, Kim JH, Exosomes neutralize synaptic-plasticity-disrupting activity of Aß assemblies in vivo., Molecular brain, 6, 2013, p47 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Klyubin, I, Wang, Q, Reed, MN, Irving, EA, Upton, N, Hofmeister, J, Cleary, JP, Anwyl, R, Rowan, MJ, Protection against Abeta-mediated rapid disruption of synaptic plasticity and memory by memantine., Neurobiology of Aging, 32, 2011, p614 - 633, Journal Article, PUBLISHED  DOI
Freir DB, Nicoll AJ, Klyubin I, Panico S, Mc Donald JM, Risse E, Asante EA, Farrow MA, Sessions RB, Saibil HR, Clarke AR, Rowan MJ, Walsh DM, Collinge J, Interaction between prion protein and toxic amyloid ß assemblies can be therapeutically targeted at multiple sites., Nature Communications, 2, (336), 2011, Journal Article, PUBLISHED  TARA - Full Text  DOI
Barry, A.E., Klyubin, I., McDonald, J.M., Mably, A.J., Farrell, M.A., Scott, M., Walsh, D.M., Rowan, M.J., Alzheimer's disease brain-derived amyloid-ß-mediated inhibition of LTP In Vivo is prevented by immunotargeting cellular prion protein, Journal of Neuroscience, 31, (20), 2011, p7259-7263 , Journal Article, PUBLISHED  TARA - Full Text
Hu, N.-W., Klyubin, I., Anwyl, R., Rowan, M.J., GluN2B subunit-containing NMDA receptor antagonists prevent Abeta-mediated synaptic plasticity disruption in vivo , Proceedings of the National Academy of Sciences of the United States of America, 106, (48), 2010, p20504-20509 , Journal Article, PUBLISHED  TARA - Full Text
Klyubin I, Betts V, Welzel AT, Blennow K, Zetterberg H, Wallin A, Lemere CA, Cullen WK, Peng Y, Wisniewski T, Selkoe DJ, Anwyl R, Walsh DM, Rowan MJ, Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization., The Journal of Neuroscience, 28, (16), 2008, p4231-7 , Journal Article, PUBLISHED  TARA - Full Text  DOI