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Professor Thorfinnur Gunnlaugsson

Professor (Chemistry)
BIOMEDICAL SCIENCES INSTITUTE

 gunnlaut@tcd.ie

 3531896 3459

Professor (CRANN)

 (3531896) 3459


Biography

Thorfinnur (Thorri) Gunnlaugsson was born in Iceland, where he received his early education in his home town of Hafnarfjörður, before obtaining a B.Sc. in Chemistry from University of Iceland (UI). During his studies at UI he visited the laboratory of Professor A. P. de Silva at Queen's University of Belfast (Northern Ireland), as a research summer student and became fascinated by the world of supramolecular photochemistry, under the magic supervision of 'A.P.'. After receiving a Ph.D. from Queen's University in 1996, under A.P.'s direction, he joined the research group of Professor David Parker at University of Durham (England) as a postdoctoral fellow. Under the guidance of David the world of coordination chemistry and lanthanide luminescence was explored and the excitement continued!

He was appointed as the Kinerton (IPSEN) Lecturer in Medicinal Organic Chemistry at the School of Chemistry, University of Dublin, Trinity College, in October 1998 and a Lecturer in Organic Chemistry in 2000. He was made a Fellow of Trinity College Dublin in 2003. In October 2004 he was appointed as an Associate Professor of Organic Chemistry at the same department and in 2008 a personal chair and Professor in Chemistry. He was a Visiting Professor at Faculty of Science and Technology- School of Life and Environmental Sciences. Deakin University, Victoria, Australia in 2005. In 2008 he was a visiting Professor in Bordeaux I CNRS in 2008.

Research Tags

  Development of ribonuclease and ribozyme mimics using lanthanide ion complexes   Synthesis & testing of novel anticancer drugs for leukaemia   Synthesis of novel contrast agents for MRI and CT   Synthesis of novel fluorescent and lanthanide luminescient chemosensors for critical care analysis   Synthesis of novel oligonucleosides and modified nucleotides

Representations

Details Date
Member, DMMC Cancer Principal Investigators, Trans-institutional grouping of Principal Investigators leading research on Cancer themes
Member, Core Technology PI's, DMMC Principal Investigators leading the development of core technology platforms.
Member, Imaging Focus Group Meeting, 1-Day meeting on Biomedical Imaging - 8th June 2004 run in conjunction with TCINFrom single cell & molecular through to organ & whole bodyLast Revised : 22 May 2004
Hegarty, I.N. and Bradberry, S.J. and Lovitt, J.I. and Delente, J.M. and Willis-Fox, N. and Daly, R. and Gunnlaugsson, T., Luminescent (metallo-supramolecular) cross-linked lanthanide hydrogels from a btp (2,3-bis(1,2,3-triazol-4-yl)picolinamide) monomer give rise to strong Tb(iii) and Eu(iii) centred emissions, Materials Chemistry Frontiers, 2023, Notes: [cited By 1], Journal Article, PUBLISHED  DOI
Hegarty, I.N. and Henwood, A.F. and Bradberry, S.J. and Gunnlaugsson, T., Generating water/MeOH-soluble and luminescent polymers by grafting 2,6-bis(1,2,3-triazol-4-yl)pyridine (btp) ligands onto a poly(ethylene-alt-maleic anhydride) polymer and cross-linking with terbium(iii), Organic and Biomolecular Chemistry, 2023, Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Ryan, G.J. and Gunnlaugsson, T. and Quinn, S.J., Hook, Line, and Sinker! Spectroscopic Studies of Bi-Modular Mono- and Bis-1,8-naphthalimide-Ru(bpy)3-conjugates as DNA "Light Switches", Inorganic Chemistry, 61, (31), 2022, p12073-12086 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Mohan, B. and Estalayo-Adrián, S. and Umadevi, D. and La Cour Poulsen, B. and Blasco, S. and McManus, G.J. and Gunnlaugsson, T. and Shanmugaraju, S., Design, Synthesis, and Anticancer Studies of a p-Cymene-Ru(II)-Curcumin Organometallic Conjugate Based on a Fluorescent 4-Amino-1,8-naphthalimide Tröger's Base Scaffold, Inorganic Chemistry, 61, (30), 2022, p11592-11599 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Gorai, T. and Lovitt, J.I. and Umadevi, D. and McManus, G. and Gunnlaugsson, T., Hierarchical supramolecular co-assembly formation employing multi-component light-harvesting charge transfer interactions giving rise to long-wavelength emitting luminescent microspheres, Chemical Science, 13, (26), 2022, p7805-7813 , Notes: [cited By 1], Journal Article, PUBLISHED  DOI
Kotova, O. and O'Reilly, C. and Barwich, S.T. and Mackenzie, L.E. and Lynes, A.D. and Savyasachi, A.J. and Ruether, M. and Pal, R. and Möbius, M.E. and Gunnlaugsson, T., Lanthanide luminescence from supramolecular hydrogels consisting of bio-conjugated picolinic-acid-based guanosine quadruplexes, Chem, 8, (5), 2022, p1395-1414 , Notes: [cited By 2], Journal Article, PUBLISHED  DOI
Calatrava-Pérez, E. and Marchetti, L.A. and McManus, G.J. and Lynch, D.M. and Elmes, R.B.P. and Williams, D.C. and Gunnlaugsson, T. and Scanlan, E.M., Real-Time Multi-Photon Tracking and Bioimaging of Glycosylated Theranostic Prodrugs upon Specific Enzyme Triggered Release, Chemistry - A European Journal, 28, (3), 2022, Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Martin, H. and Lázaro, L.R. and Gunnlaugsson, T. and Scanlan, E.M., Glycosidase activated prodrugs for targeted cancer therapy, Chemical Society Reviews, 51, (23), 2022, p9694-9716 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Keane, P.M. and Zehe, C. and Poynton, F.E. and Bright, S.A. and Estayalo-Adrián, S. and Devereux, S.J. and Donaldson, P.M. and Sazanovich, I.V. and Towrie, M. and Botchway, S.W. and Cardin, C.J. and Williams, D.C. and Gunnlaugsson, T. and Long, C. and Kelly, J.M. and Quinn, S.J., Time-resolved infra-red studies of photo-excited porphyrins in the presence of nucleic acids and in HeLa tumour cells: insights into binding site and electron transfer dynamics, Physical Chemistry Chemical Physics, 24, (44), 2022, p27524-27531 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Lynes, A.D. and Lovitt, J.I. and Rotella, C. and Boland, J.J. and Gunnlaugsson, T. and Hawes, C.S., Crystal engineering studies of a series of pyridine-3,5-dicarboxamide ligands possessing alkyl ester arms, and their coordination chemistry, Results in Chemistry, 4, (100679), 2022, Notes: [cited By 0], Journal Article, PUBLISHED  DOI
  

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Hawes C.S, Lynes A.D, Byrne K, Schmitt W, Ryan G, Mobius M.E, Gunnlaugsson T, A resilient and luminescent stimuli-responsive hydrogel from a heterotopic 1,8-naphthalimide-derived ligand, Chemical Communications, 53, (44), 2017, p5989 - 5992, Journal Article, PUBLISHED
Meriel Huggard, Sensor Research, US-Ireland F&D Partnership - Sensor Workshop, Crowne Plaza Hotel, Dublin, 20-21 February 2007, 2007, Poster, PUBLISHED
Stanley E. Porter, Michael A. Hayes and David Tombs, eds, Images of Christ, Sheffield Academic Press, Sheffield, 1997, Book, PUBLISHED

  

Awards and Honours

Award Date
Erskine Fellowship 2009

Research Interests

Description Of Research Interests

His research interests are in theareas of supramolecular organic and inorganic chemistry and bio and medicinal chemistry, with emphasis on the recognition and targeting of biologically important ions and molecules.