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Dr. Clair Gardiner

Professor (Biochemistry)


  IMMUNOLOGY
Details Date From Date To
British Society for Immunology
Irish Society for Immunology
Woods E, Mena A, Sierpinska S, Carr E, STTAR Bioresource, Hagan R, Crowley J, Bergin C, Clark D, Brophy C, Macallan D, Gardiner CM., Reduced IFNL1 and/or IFNL2, but not IFNL3 is associated with worse outcome in patients with COVID-19., Clinical and experimental immunology, 2024, puxae047 , Journal Article, PUBLISHED  DOI
Slattery K., Breheny M., Woods E., Keating S., Brennan K., Rooney C., Augustine S., Ryan A., Owens C., Gardiner C.M., Heightened metabolic responses in NK cells from patients with neuroblastoma suggests increased potential for immunotherapy, Frontiers in Oncology, 12, 2022, Journal Article, PUBLISHED  DOI
O'Brien, K.L. and Assmann, N. and O'Connor, E. and Keane, C. and Walls, J. and Choi, C. and Oefner, P.J. and Gardiner, C.M. and Dettmer, K. and Finlay, D.K., De novo polyamine synthesis supports metabolic and functional responses in activated murine NK cells, European Journal of Immunology, 51, (1), 2021, p91-102 , Notes: [cited By 7], Journal Article, PUBLISHED  DOI
Nidhi Kedia-Mehta, Laura Tobin, Vanessa Zaiatz-Bittencourt, Marta M Pisarska, Conor De Barra, Chloe Choi, Einas Elamin, Donal O'Shea , Clair M Gardiner, David K Finlay, Andrew E Hogan , Cytokine-induced natural killer cell training is dependent on cellular metabolism and is defective in obesity, Blood Advances, 5, (21), 2021, p4447-4455 , Journal Article, PUBLISHED
Slattery K., Woods E., Zaiatz-Bittencourt V., Marks S., Chew S., Conroy M., Goggin C., Maceochagain C., Kennedy J., Lucas S., Finlay D.K., Gardiner C.M., TGFß drives NK cell metabolic dysfunction in human metastatic breast cancer, Journal for ImmunoTherapy of Cancer, 9, (2), 2021, Journal Article, PUBLISHED  DOI
Jessica F. Walls, Jeff J. Subleski, Erika M. Palmieri, Marieli Gonzalez Cotto, Clair M. Gardiner, Daniel W. McVicar, David K. Finlay, Metabolic but not transcriptional regulation by PKM2 is important for Natural Killer cell responses, eLIFE, 2020, Journal Article, PUBLISHED  TARA - Full Text  DOI
Slattery, K. and Gardiner, C.M., NK Cell Metabolism and TGFβ â€" Implications for Immunotherapy, Frontiers in Immunology, 10, (2915), 2019, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
Cluxton, C.D. and Spillane, C. and O†Toole, S.A. and Sheils, O. and Gardiner, C.M. and O†Leary, J.J., Suppression of Natural Killer cell NKG2D and CD226 anti-tumour cascades by platelet cloaked cancer cells: Implications for the metastatic cascade, PLoS ONE, 14, (3), 2019, Notes: [cited By 2], Journal Article, PUBLISHED  TARA - Full Text  DOI
Hartnell, F. and Brown, A. and Capone, S. and Kopycinski, J. and Bliss, C. and Makvandi-Nejad, S. and Swadling, L. and Ghaffari, E. and Cicconi, P. and Sorbo, M.D. and Sbrocchi, R. and Esposito, I. and Vassilev, V. and Marriott, P. and Gardiner, C.M. and Bannan, C. and Bergin, C. and Hoffmann, M. and Turner, B. and Nicosia, A. and Folgori, A. and Hanke, T. and Barnes, E. and Dorrell, L., A novel vaccine strategy employing serologically different chimpanzee adenoviral vectors for the prevention of HIV-1 and HCV coinfection, Frontiers in Immunology, 10, (JAN), 2019, Notes: [cited By 5], Journal Article, PUBLISHED  TARA - Full Text  DOI
Gardiner, C.M., How to wake a killer, Nature Immunology, 20, (12), 2019, p1561-1563 , Journal Article, PUBLISHED  DOI
  

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Gardiner CM, Breakthroughs in understanding NK cell metabolism, Seminar Series, Stanford University, July, 2014, Prof. Peter Parham, Invited Talk, PRESENTED
Gardiner CM, Natural Killer cells in cancer, Seminar Series, NUI Maynooth, November, 2013, Prof. Paul Moynagh, Invited Talk, PUBLISHED