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Dr. Emma Creagh

Associate Professor (Biochemistry)
      
Profile Photo

Dr. Emma Creagh

Associate Professor (Biochemistry)


  CANCER   CANCER IMMUNOLOGY   CASPASES   Inflammasome-mediated inflammation   INFLAMMATION
Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
Details Date From Date To
Irish Association for Cancer Research (Senior Council Member, 2020-2024) 2000 Present
American Society for Immunology 2014 Present
International Society for Mucosal Immunology 2015 Present
Irish Society of Gastroenterology 2012 Present
Irish Society of Immunology 2010 Present
Irish Epithelial Physiology Group 2016 Present
C Mchale, S Sharma, Aidan Agnew, Chiara DeSanti, Emma M. Creagh, Sinéad C. Corr, K Boland, Jennifer K. Dowling, P0099 Investigating Arginase-2 target site blockers as a therapeutic strategy in acute Inflammatory Bowel Disease, Journal of Crohn s and Colitis, 20, (Supplement_1), 2026, Journal Article, PUBLISHED  DOI
Ana López"Garza, David H. James, Emma M. Creagh, James T. Murray, Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs, Molecular Oncology, 19, (11), 2025, p3427 - 3444, p3427-3444 , Journal Article, PUBLISHED  DOI
Laura Kane, Brian Flood, Joan Manils, Donna E McSkeane, Aoife P. Smith, Miriam Tosetto, Fatema Alalawi, Joanna Fay, Elaine W. Kay, Cara Dunne, Stephen McQuaid, Maurice B. Loughrey, Jacintha O"Sullivan, Elizabeth J. Ryan, Kieran Sheahan, Glen Doherty, Emma M. Creagh, Caspase-4 has potential utility as a colorectal tissue biomarker for dysplasia and early-stage cancer, Gastro Hep Advances, 4, (2), 2024, p100552 - 100552, p100552-100552 , Journal Article, PUBLISHED  DOI
Muñoz-Wolf, N. and Ward, R.W. and Hearnden, C.H. and Sharp, F.A. and Geoghegan, J. and O'Grady, K. and McEntee, C.P. and Shanahan, K.A. and Guy, C. and Bowie, A.G. and Campbell, M. and Roces, C.B. and Anderluzzi, G. and Webb, C. and Perrie, Y. and Creagh, E. and Lavelle, E.C., Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles, Cell Reports Medicine, 4, (1), 2023, Notes: [cited By 1], Journal Article, PUBLISHED  TARA - Full Text  DOI
Ryan, T.A.J. and Hooftman, A. and Rehill, A.M. and Johansen, M.D. and Brien, E.C.O. and Toller-Kawahisa, J.E. and Wilk, M.M. and Day, E.A. and Weiss, H.J. and Sarvari, P. and Vozza, E.G. and Schramm, F. and Peace, C.G. and Zotta, A. and Miemczyk, S. and Nalkurthi, C. and Hansbro, N.G. and McManus, G. and O†Doherty, L. and Gargan, S. and Long, A. and Dunne, J. and Cheallaigh, C.N. and Conlon, N. and Carty, M. and Fallon, P.G. and Mills, K.H.G. and Creagh, E.M. and Donnell, J.S.O. and Hertzog, P.J. and Hansbro, P.M. and McLoughlin, R.M. and Wygrecka, M. and Preston, R.J.S. and ZasÅ'ona, Z. and Neill, L.A.J.O., Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon, Nature Communications, 14, (1), 2023, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
Aoife P. Smith, Emma M. Creagh, Caspase-4 and -5 Biology in the Pathogenesis of Inflammatory Bowel Disease, Frontiers in Pharmacology, 13, 2022, p919567 - 919567, p919567-919567 , Review Article, PUBLISHED  DOI
Evaluating host responses to Helicobacter pylori using ELISA and Western Blot. in, Methods in Molecular Biology, Springer, 2021, pp175-190 , [C. Nulty, G. Barber, E. Flis, E.M. Creagh. ], Book Chapter, PUBLISHED  DOI
E. Flis, G. Barber, C. Nulty, B. Keogh, P. McGuirk, A. Anand, J. O'Sullivan, M. Quante, E.M. Creagh. , Identification of TLR2 signalling mechanisms which Contribute to Barrett's and Oesophageal Adenocarcinoma Disease Progression, Cancers (Basel) , 13, (9), 2021, p2065 - 2081, Journal Article, PUBLISHED  DOI
Agnew, A., Nulty, C., Creagh, E.M., Regulation, Activation and Function of Caspase-11 during Health and Disease., International Journal of Molecular Science, 22, (4), 2021, p1506-, Journal Article, PUBLISHED  DOI
Zaslona Z, Flis E, Nulty C, Kearney J, Fitzgerald R, Douglas AR, McNamara D, Smith S, O'Neill LAJ, Creagh EM., Caspase-4: A Therapeutic Target for Peptic Ulcer Disease, Immunohorizons, 4, (10), 2021, p627 - 633, Journal Article, PUBLISHED  DOI
  

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Creagh, E.M., Contribution of Inflammatory caspases to IBD & CRC, INITIative Network meeting, Dublin, Ireland, 23rd November 2018, 2018, Invited Talk, PRESENTED
Flis, E and Creagh, E.M., Role of TLR2 in Oesophageal Adenocarcinoma Progression, Training in Cancer Mechanisms & Therapeutics Meeting, Queens University, Belfast, 16th April 2018, 2018, Oral Presentation, PRESENTED
Caspase detection and analysis in, editor(s)Edited by D. Hughes and H. Mehmet , Cell Proliferation and Apoptosis , Oxford, UK, Bios Scientific Publishers, 2003, pp233 - 253, [Creagh, E. M., Adrain C., and S.J Martin], Book Chapter, PUBLISHED
Caspase cascades in apoptosis in, editor(s)M. Los and H. Walczak , In Caspases-Their role in Cell Death and Cell Survival, New York, USA, Landes Bioscience/Kluwer Academic/Plenum Publishers, 2002, pp41 - 51, [S.J Martin], Book Chapter, PUBLISHED

  


Award Date
Wellcome Trust Career Development Fellowship 2006-2011
Broad Medical Research Program Fellowship 2010-2012
TCD Pathfinder Award 2015
Winner - Oral presentation - Irish Society of Gastroenterology Meeting 2016
Voted 'Favorite Woman in Science' 2017, 2018 and 2019 by TCD General Science Students 2017-2019
Senior Council Member - Irish Association for Cancer Research (IACR). 2020