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Dr. Donal Cox

Research Fellow (Clinical Medicine)

 docox@tcd.ie

 


Research Tags

  Ageing   HUMAN MACROPHAGES   Immunometabolism   Infection and immunity   NEURODEGENERATIVE DISEASE   TB immunology
Murphy DM, Walsh A, Stein L, Petrasca A, Cox DJ, Brown K, Duffin E, Jameson G, Connolly SA, O'Connell F, O'Sullivan J, Basdeo SA, Keane J, Phelan JJ., Human Macrophages Activate Bystander Neutrophils' Metabolism and Effector Functions When Challenged with Mycobacterium tuberculosis., International journal of molecular sciences, 25, (5), 2024, p2898 , Journal Article, PUBLISHED  DOI
Murphy, D.M., Cox, D.J., Connolly, S.A., Breen, E.P., Brugman, A.A.I., Phelan, J.J., Keane, J., Basdeo, S.A., Trained immunity is induced in humans after immunization with an adenoviral vector COVID-19 vaccine, Journal of Clinical Investigation, 133, (2), 2023, Journal Article, PUBLISHED  DOI
Christina Cahill, Dónal J. Cox, Fiona O'Connell, Sharee A. Basdeo, Karl M. Gogan, Cilian Ó'Maoldomhnaigh, Jacintha O'Sullivan, Joseph Keane and James J. Phelan., The Effect of Tuberculosis Antimicrobials on the Immunometabolic Profiles of Primary Human Macrophages Stimulated with Mycobacterium tuberculosis, International Journal of Molecular Sciences, 2021, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Cilian Ó Maoldomhnaigh, Donal J Cox, James Joseph Phelan, Karl M. Gogan, Kate McQuaid, Amy Martina Coleman, Sharee Ann Basdeo and Joseph Keane., Lactate alters metabolism in human macrophages and improves their ability to kill Mycobacterium tuberculosis, Frontiers in Immunology, 2021, Journal Article, PUBLISHED
Ó Maoldomhnaigh C, Cox DJ, Phelan JJ, Malone FD, Keane J, Basdeo SA., The Warburg Effect Occurs Rapidly in Stimulated Human Adult but Not Umbilical Cord Blood Derived Macrophages., Frontiers in immunology, 12, 2021, p657261 , Journal Article, PUBLISHED  DOI
Cahill C, O'Connell F, Gogan KM, Cox DJ, Basdeo SA, O'Sullivan J, Gordon SV, Keane J, Phelan JJ., The Iron Chelator Desferrioxamine Increases the Efficacy of Bedaquiline in Primary Human Macrophages Infected with BCG., International journal of molecular sciences, 22, (6), 2021, Journal Article, PUBLISHED  DOI
Cox, D.J., Coleman, A.M., Gogan, K.M., Phelan, J.J., Maoldomhnaigh, C., Dunne, P.J., Basdeo, S.A. and Keane, J., Inhibiting histone deacetylases in human macrophages promotes glycolysis, IL-1β and T helper cell responses to Mycobacterium tuberculosis, Frontiers in Immunology, 2020, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Phelan J.J., McQuaid, K., Kenny C., Gogan K.M., Cox D.J., Basdeo S.A., O'Leary S., Tazoll S.C., Ó Maoldomhnaigh C., O'Sullivan M.P., O'Neill LA, O'Sullivan M.J. & Keane J., Desferrioxamine supports metabolic function in primary human macrophages infected with Mycobacterium tuberculosis, Frontiers in Immunology, 2020, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Nazmi, A., Field, R.H., Griffin, E.W., Haugh, O., Hennessy, E., Cox, D., Reis, R., Tortorelli, L., Murray, C.L., Lopez-Rodriguez, A.B., Lavelle, E.C., Dunne, A. and Cunningham,C. , Chronic neurodegeneration induces Type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression, Glia, 67, 2019, p1254 - 1276 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Dunne, Pádraic J., Lynch, Julie, Prihodova, Lucia, O'Leary, Caoimhe, Ghoreyshi, Atiyeh, Basdeo, Sharee A., Cox, Donal J., Breen, Rachel, Sheikhi, Ali, Carroll, Áine, Walsh, Cathal, McMahon, Geraldine, White, Barry, Burnout in the emergency department: Randomized controlled trial of an attention-based training program, Journal of Integrative Medicine, 2019, Journal Article, PUBLISHED  DOI
  

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