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Dr. Fabio Boylan

Associate Professor (Pharmacy)
25/6/7 WESTLAND ROW


Born in Rio de Janeiro, Brazil, in 15 of February of 1972. Fabio Boylan studied Pharmacy at Rio de Janeiro Federal University, in Rio de Janeiro, Brazil. From February 1996 to February 1998, he was Lecturer at the Department of Pharmacognosy, Faculdade de Farmacia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. His Master project "Phylogenetic Trends within Lamiiflorae" was sponsored by CNPq, a Brazilian Governmental Agency for 1.5 years and he got the degree after being evaluated by Dr. Otto Richard Gottlieb. His Ph.D. project "Chemical and Pharmacological Studies on Raphiodon echinus and Marsypianthes chamaedrys" was sponsored by CAPES, another Brazilian Governmental Agency. In several years he was awarded with grants from FAPERJ (Rio de Janeiro Research Supporting Agency) and FINEP in 2003 when he had the opportunity to chair the XII Italian-Latin-American Conference on Ethnomedicine. Also in 2003 he was awarded with a special grant from CNPq due to his scientific collaboration to the Brazilian Science. Fabio stepped up as a senior lecturer at the Faculty of Pharmacy, Federal University of Rio de Janeiro in 1998. In 2006, he started his sabbatical year in the School of Pharmacy and Pharmaceutical Sciences, TCD, where he further served as a research coordinator from 2007-2008 and now is a full time lecturer in Pharmacognosy. He acts an ad hoc reviewer for the following scientific journals: Brazilian Journal of Pharmacognosy, Brazilian Journal of Medicinal Plants, Brazilian Journal of Microbiology, Brazilian Journal of Pharmaceutical Sciences, Phytochemistry, Iheringia Zoologia (Section Botany), Phytotherapy Research, Current Medicinal Chemistry, African Journal of Pharmacology and Pharmaceutical Sciences, Molecules, Frontiers in Pharmacology, Antioxidants, Journal of Chromatography, among others.
  Antiinflammatory drugs   Biochemistry, metabolism   Chemistry of drug metabolism   Chemistry of drug receptor interactions   Development of drugs for malaria, Cancer and inflammatory diseases   Drug development   Drug discovery   Herbal medicine   Medicinal Chemistry   Medicinal plants   Microencapsulation methodologies   Molecular markers and recognition   Molecular systematics   Organic chemistry   Pharmaceutical products   Pharmacognosy   Pharmacological Sciences   Phytochemical and pharmacological evaluations of native and foreign plants   Phytomedicines   Plant and algal cell monocultures   Plant Biochemistry   Plant biology   Plant systematics   Plant tissue culture   Secondary plant metabolism   Traditional and Indigenous health systems in developing countries
 Orbignya speciosa (Arecacea) as a potencial source of novel therapeutic agents: from traditional medicine information to the pharmacological evaluation of its chemical constituents.
 Chemical and pharmacological studies on Jambu and Piquia, two medicinal plants from the Amazon Region: development of new health products with nutraceutical and medicinal properties.
 Chemical and Pharmacological studies on Medicinal Plants from Kazakh Flora
 Investigation on the anti-inflammatory properties of selected Saudi Medicinal Plants and correlation of their activity with their chemistry
 The scents of St. Stephen's Green: would a Dublin city centre park be hiding a chemical treasure?

Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
French Fluent Basic Medium
Italian Fluent Medium Medium
Portuguese Fluent Fluent Fluent
Spanish Fluent Medium Medium
Details Date From Date To
Phytochemical Society of North America 1992
Brazilian Society of Pharmacognosy 2000
GA - Society for Medicinal Plant and Natural Product Research 2022
Mladenovic Marko Z, Ristic Milenko N, Bogdanovic Andrija I, Ristic Novica R, Boylan Fabi, Radulovic Niko S, Wax Composition of Serbian Dianthus spp. (Caryophyllaceae): Identification of New Metabolites and Chemotaxonomic Implications, PLANTS-BASEL, 12, (11), 2023, Journal Article, PUBLISHED  DOI
Silveira Damari, Boylan Fabio, Medicinal Plants: Advances in Phytochemistry and Ethnobotany, PLANTS-BASEL, 12, (8), 2023, Journal Article, PUBLISHED  DOI
Fernandes Felipe Hugo Alenca, Soares Sabrina da Silv, Bekbolatova Elmir, Boylan Fabio, Salgado Herida Regina Nune, Pharmacological, toxicological and phytochemical analysis of Spondias dulcis parkinson, NATURAL PRODUCT RESEARCH, 38, (6), 2024, p10149 - 1053, Journal Article, PUBLISHED  DOI
Radulovic Niko S, Mladenovic Marko Z, Dekic Milan S, Boylan Fabio, Synthesis of Small Libraries of Natural Products: Part II: Identification of a New Natural Product from the Essential Oil of Pleurospermum austriacum (L.) Hoffm. (Apiaceae), MOLECULES, 28, (12), 2023, Journal Article, PUBLISHED  DOI
MENSOR, L. L. ; MENEZES, F. S. ; LEITÃO, Gilda Guimarães ; REIS, A. S. ; SANTOS, T. C. ; COUBE, C. S. ; LEITÃO, Suzana Guimarães , Screening of Brazilian Plant Extracts for Antioxidant Activity by the Use of DPPH Free Radical Method, Phytotherapy Research, 15, (2), 2001, p127 - 130, Journal Article, PUBLISHED  DOI
SILVA, Carmelita G ; HERDEIRO, R S ; MATHIAS, C J ; PANEK, Anita Dolly ; SILVEIRA, Cristiane Silva ; RODRIGUES, Verônica Pinto ; RENNÓ, Magdalena Nascimento ; FALCÃO, Deborah Quintanilha ; CERQUEIRA, Débora Malta ; MINTO, Andréa Barreto Mattos ; NOGUEIRA, Fábio Luis Pereira ; QUARESMA, Carla Holandino ; SILVA, Joaquim Fernando Mendes da ; MENEZES, F. S. ; ELEUTHERIO, Elis Cristina de Araújo, Evaluation of Antioxidant Activity of Brazilian Plants, Pharmacological Research, 52, (3), 2005, p229 - 233, Journal Article, PUBLISHED  DOI
MATHEUS, Maria Eline ; BERRONDO, Luciane Fátima ; VIEITAS, Eniana Campolina ; MENEZES, F. S. ; FERNANDES, Patrícia Dias , Evaluation of the Antinociceptive Properties from Brillantaisia palisotii Lindau Stems Extracts, Journal of Ethnopharmacology, 102, (3), 2005, p377 - 381, Journal Article, PUBLISHED  DOI
Amado, NG; Cerqueira, DM; Menezes, FS; Silva, JFM; Neto, V.M.; Abreu, J.G., Isoquercitrin isolated from Hyptis fasciculata reduces glioblastoma cell proliferation and changes B-catenin cellular localization, Anti Cancer Drugs, 20, (7), 2009, p543 - 552, Journal Article, PUBLISHED  DOI
de Sousa, VP, Crean, J, Borges, VRD, Rodrigues, CR, Tajber, L, Boylan, F, Cabral, LM, Nanostructured systems containing babassu (Orbignya speciosa) oil as a potential alternative therapy for benign prostatic hyperplasia, INTERNATIONAL JOURNAL OF NANOMEDICINE, 8, 2013, p3129-3139 , Journal Article, PUBLISHED  DOI
C.G. Silva, R. Raulino, D.M. Cerqueira, M.D. Pereira, A.D. Panek, J.F.M. Silva, E.C.A. Eleutherio, F.S. Menezes., In vitro and in vivo determination of antioxidant activity and mode ofaction of isoquercitrin and Hyptis fasciculata, Phytomedicine, 2009, Journal Article, PUBLISHED  DOI
  

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Award Date
Cum Laude Diploma 1992
Global Relations Certificate of Excellence 2015-2016
My line of research can be summarized by: 1- The discovery of the scientific basis of natural medicines used by disadvantaged communities (poor or absent of primary health care) or communities with a strong belief in Medicinal Plants usage is a crucial point of my research. 2- The evaluation of the chemistry of Bioactive Volatile Organic Compounds (BVOCs) and their importance in food and Pharmacy became a more robust aspect of my research since my last application. 3- The discovery of harmful or even severely toxic effects from various natural medicines is constantly under scrutiny in my research. Based on recent findings of my current research in the School of Pharmacy and Pharmaceutical Sciences - TCD, the main aims for future research are outlined below. A) To investigate medicinal plants from Saudi Arabia used locally as anti-inflammatories. It aims to understand further the molecular mechanisms that explain their activities. B) A similar approach will be developed concerning Brazilian Plants I have been working with in conjunction with my Brazilian Collaborators. The aim here is to validate the popular use of Brazilian medicinal plants and their molecular interaction with biological systems. C) Continue the research developed in conjunction with the Republic of Kazakhstan. As a visiting professor at the Kazakh National Medical University, specifically in the area of Natural Products using a similar approach to the ethnopharmacological understanding of their plants, the aim is to validate endemic plants' chemical and pharmacological properties. D) St. Stephen's Green Park houses over 100 species of plants belonging to over 20 different botanical families. One of my following projects proposes the investigation of the essential oil (EO) constituents of plants growing in the park. The potential mechanism of their anticancer activity will be investigated for the EOs and EO constituents. The best candidates from those with the highest anticancer activity may be selected for further research in Pharmaceutics for their formulation using reverse micellar and silver nanoparticle production. Since my last promotion, I have published 50 research papers, with an average IF for those at 4.6 (average IF in the area of Natural Products is around 3.5). These papers were published due to the intense supervision of graduate students both in Ireland and outside of Ireland. My research is of international significance and has been widely published in academia, amongst the journals considered most favourably in the field of Pharmacy and Natural Products. I have achieved a high level of publication over a sustained period in international and peer-reviewed journals for over 15 years. According to the Researchgate database, my research interest score (2,640) is higher than 98% of Pharmacy scientists, I have authored a total of 124 publications that have had 33,308 reads and 4,808 citations. My Google Scholar H-index is 30, and my i10 index is 66. I have an upward trajectory in terms of publication citation, with a peak in 2021 due to my most downloaded publication from 2020 in Frontiers in Pharmacology related to COVID-19 - 365,900 views and 16,400 downloads.