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Professor Matthew Campbell

Professor (Genetics)

Professor (Trinity Inst. of Neurosciences (TCIN))

  AGE-RELATED MACULOPATHY   Alzheimer's Disease   BLOOD-BRAIN-BARRIER   Cell signalling, proliferation & differentiation   Cellular Biology   ENDOTHELIAL CELLS   Genetics   INFLAMMATION   Molecular Biology   Molecular Genetics   Neurobiology   neurodegeneration   Neuroscience   siRNA technology   TIGHT JUNCTIONS   Transgenics   Vision
 Eye-D: Therapeutic target identification for degenerative eye disease
 Retina Rhythm:Investigating the role of the inner retina in age-related macular degeneration (AMD)

Details Date
Member of the scientific review committee of Moorfields Eye Charity, UK. 2020 - present
Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
Details Date From Date To
Associate Editor, Fluids and Barriers of the CNS 2021 Present
Member of International Society for Eye Research. 2010-present: International Brain Barriers Society (IBBS). 2014 Present
Hashimoto Y, Greene C, Munnich A, Campbell M, The CLDN5 gene at the blood-brain barrier in health and disease., Fluids and barriers of the CNS, 2023, Journal Article, PUBLISHED  DOI
O†Riordan, M.M. and Cahill, M.T. and Campbell, M. and Kearney, H., Evaluation of Inflammation in the Peripheral Multiple Sclerosis Retina Using Ultra-Widefield Optical Coherence Tomography: A Pilot Study, Ophthalmic Surgery Lasers and Imaging Retina, 54, (10), 2023, p586-588 , Notes: [cited By 1], Journal Article, PUBLISHED  DOI
Desguerre, I. and Aubart, M. and Hashimoto, Y. and Poirier, K. and Kaminska, A. and Alison, M. and Boddaert, N. and Munnich, A. and Campbell, M., Reply: De novo mutations in CLDN5: alternating hemiplegia of childhood or not?, Brain, 146, (8), 2023, pE59-E60 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
O†Riordan, M. and Hudson, N. and O†Callaghan, J. and Campbell, M. and Cahill, M., Near-Complete Drusen Resolution With Brolucizumab: A Mechanism for Proinflammatory Mediated Drusen Clearance?, Ophthalmic Surgery Lasers and Imaging Retina, 54, (6), 2023, p371-374 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
O†Callaghan, J. and Delaney, C. and O†Connor, M. and van Batenburg-Sherwood, J. and Schicht, M. and LÃŒtjen-Drecoll, E. and Hudson, N. and Dhubhghaill, S.N. and Humphries, P. and Stanley, C. and Keravala, A. and Chalberg, T. and Lawrence, M.S. and Campbell, M., Matrix metalloproteinase-3 (MMP-3)â€"mediated gene therapy for glaucoma, Science Advances, 9, (16), 2023, Notes: [cited By 5], Journal Article, PUBLISHED  DOI
Dion-Albert, L. and Dudek, K.A. and Russo, S.J. and Campbell, M. and Menard, C., Neurovascular adaptations modulating cognition, mood, and stress responses, Trends in Neurosciences, 46, (4), 2023, p276-292 , Notes: [cited By 7], Journal Article, PUBLISHED  DOI
Muñoz-Wolf, N. and Ward, R.W. and Hearnden, C.H. and Sharp, F.A. and Geoghegan, J. and O'Grady, K. and McEntee, C.P. and Shanahan, K.A. and Guy, C. and Bowie, A.G. and Campbell, M. and Roces, C.B. and Anderluzzi, G. and Webb, C. and Perrie, Y. and Creagh, E. and Lavelle, E.C., Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles, Cell Reports Medicine, 4, (1), 2023, Notes: [cited By 1], Journal Article, PUBLISHED  DOI
Lay, C.S. and Thomas, D.A. and Evans, J.P. and Campbell, M. and McCombe, K. and Phillipou, A.N. and Gordon, L.J. and Jones, E.J. and Riching, K. and Mahmood, M. and Messenger, C. and Carver, C.E. and Gatfield, K.M. and Craggs, P.D., Erratum: Development of an intracellular quantitative assay to measure compound binding kinetics (Cell Chemical Biology (2022) 29(2) (287â€"299.e8), (S2451945621003585), (10.1016/j.chembiol.2021.07.018)), Cell Chemical Biology, 2023, p1692 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Brennan, D. and Delaney, C. and Farrell, M. and Campbell, M. and Doherty, C.P., Polypathology-associated neurodegeneration after remote head injury, Clinical Neuropathology, 42, (6), 2023, p201-211 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Dion-Albert, L. and Cadoret, A. and Doney, E. and Kaufmann, F.N. and Dudek, K.A. and Daigle, B. and Parise, L.F. and Cathomas, F. and Samba, N. and Hudson, N. and Lebel, M. and Aardema, F. and Ait Bentaleb, L. and Beauchamp, J. and Bendahmane, H. and Benoit, E. and Bergeron, L. and Bertone, A. and Bertrand, N. and Berube, F.-A. and Blanchet, P. and Boissonneault, J. and Bolduc, C.J. and Bonin, J.-P. and Borgeat, F. and Boyer, R. and Breault, C. and Breton, J.-J. and Briand, C. and Brodeur, J. and Brule, K. and Brunet, L. and Carriere, S. and Chartrand, C. and Chenard-Soucy, R. and Chevrette, T. and Cloutier, E. and Cloutier, R. and Cormier, H. and Cote, G. and Cyr, J. and David, P. and De Benedictis, L. and Delisle, M.-C. and Deschenes, P. and Desjardins, C.D. and Desmarais, G. and Dubreucq, J.-L. and Dumont, M. and Dumais, A. and Ethier, G. and Feltrin, C. and Felx, A. and Findlay, H. and Fortier, L. and Fortin, D. and Fortin, L. and Francois, N. and Gagne, V. and Gagnon, M.-P. and Gignac-Hens, M.-C. and Giguere, C.-E. and Godbout, R. and Grou, C. and Guay, S. and Guillem, F. and Hachimi-Idrissi, N. and Herry, C. and Hodgins, S. and Homayoun, S. and Jemel, B. and Joyal, C. and Kouassi, E. and Labelle, R. and Lafortune, D. and Lahaie, M. and Lahlafi, S. and Lalonde, P. and Landry, P. and Lapaige, V. and Larocque, G. and Larue, C. and Lavoie, M. and Leclerc, J.-J. and Lecomte, T. and Lecours, C. and Leduc, L. and Lelan, M.-F. and Lemieux, A. and Lesage, A. and Letarte, A. and Lepage, J. and Levesque, A. and Lipp, O. and Luck, D. and Lupien, S. and Lusignan, F.-A. and Lusignan, R. and Luyet, A.J. and Lynhiavu, A. and Melun, J.-P. and Morin, C. and Nicole, L. and Noel, F. and Normandeau, L. and O†Connor, K. and Ouellette, C. and Parent, V. and Parizeau, M.-H. and Pelletier, J.-F. and Pelletier, J. and Pelletier, M. and Plusquellec, P. and Poirier, D. and Potvin, S. and Prevost, G. and Prevost, M.-J. and Racicot, P. and Racine-Gagne, M.-F. and Renaud, P. and Ricard, N. and Rivet, S. and Rolland, M. and Sasseville, M. and Safadi, G. and Smith, S. and Smolla, N. and Stip, E. and Teitelbaum, J. and Thibault, A. and Thibault, L. and Thibault, S. and Thomas, F. and Todorov, C. and Tourjman, V. and Tranulis, C. and Trudeau, S. and Trudel, G. and Vacri, N. and Valiquette, L. and Vanier, C. and Villeneuve, K. and Villeneuve, M. and Vincent, P. and Wolfe, M. and Xiong, L. and Zizzi, A. and Campbell, M. and Turecki, G. and Mechawar, N. and Menard, C., Vascular and blood-brain barrier-related changes underlie stress responses and resilience in female mice and depression in human tissue, Nature Communications, 13, (1), 2022, Notes: [cited By 1], Journal Article, PUBLISHED  DOI

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1. K Mulfaul, E Ozaki, K Brennan, M Campbell, S Doyle, Investigating a role for Toll like receptor signaling in the pathogenesis of Age Related Macular Degeneration (AMD). , Investigative Ophthalmology & Visual Science, , ARVO, Seattle, 57 (12), (5010-5010), 2016, Conference Paper, PUBLISHED
10. C Doherty, E Wallace, M Campbell, P Humphries, Evaluation of an Acute RNAi-Mediated Therapeutic for Visual Dysfunction Associated with Traumatic Brain Injury., Neurology 2012, SAINT JAMES HOSPITAL DUBLIN (IRELAND), 2012, Conference Paper, PUBLISHED
12. GA Grant, C Wilson, M Campbell, S Li, P Humphries, A Johnson, Reversible Opening of the Blood-brain Barrier by Targeted Suppression of Claudin 5 To Enhance Drug Delivery into Brain Tumors. , Annals of Neurology , 2012, Conference Paper, PUBLISHED
Brankin B, Campbell M, Humphries M, Kennan A, Kenna P, Humphries P, Zonulas occluden 1 expression in retinas from Rho-/-C129 mice, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 45, (Suppl. 2), 2004, ppU179 - U179, Meeting Abstract, PUBLISHED


Award Date
Science Foundation Ireland, Young Researcher of the year 2020
European Research Council Consolidator Award 2020
Irish Research Council Laureate Award. 2018
Association for Ocular Pharmacology and Therapeutics, National Eye Institute (NEI) award 2015
Association for Research in Vision and Ophthalmology, NEI travel Award 2015
Genentech/ARVO fellowship in recognition of my research on AMD 2015
Science Foundation Ireland, President of Ireland Young Researcher Award (PIYRA) 2013
"Pro-Retina" travel award for XVth International Symposium on Retinal Degenerations 2012
Appointed Senior Research Fellow, TCD 2012
Roche Research Award, Smurfit Institute of Genetics 2010
Fighting Blindness Ireland Research Scholarship 2002