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Dr. Arun Bokde

Associate Professor (Psychiatry)
LLOYD INSTITUTE

Associate Professor (Trinity Inst. of Neurosciences (TCIN))

Associate Professor (School Office - Medicine)


Arun Bokde is Associate Professor in Neuroimaging in the Discipline of Psychiatry, School of Medicine, at Trinity College Dublin. He leads the Cognitive Systems Group, is a principal investigator in the Trinity College Institute of Neuroscience (TCIN), and a member of the Global Brain Health Institute (GBHI). His initial appointment at Trinity College Dublin was as SFI Stokes Lecturer in Biostatistical Imaging. Arun Bokde is the coordinator of the consortium NETHATE (https://nethate-itn.eu) funded by EU-H2020 Marie Sk"odowska-Curie Actions. The project he leads is to investigate the neural underpinnings of hate. He is a member of the multi-centre consortium Imaging in Genetics (IMAGEN), a study of high-risk behaviors and mental disorders in adolescence. In addition, he is a member in the Neonatal and Children"s Brain Consortium Ireland (https://nbci.ie), focused on research in the neonatal brain and neonatal brain injury. Before coming to Trinity College Dublin he was a Research Scientist at Ludwig Maximilian University in Munich, Germany; and previously he was a Postdoctoral Research Fellow at the National Institute on Aging and at the National Institute of Mental Health, both at the National Institutes of Health (USA). His first post-doctoral position was at Northwestern University (USA). He obtained his PhD degree at the University of Texas at Austin. He has published widely on the risk factors that lead to the development of mental health disorders in young and older populations.
  Age related diseases   Ageing, memory and other cognitive processes   Ageing, stroke, dementia   Alzheimer's disease   Biostatistical methods   Development, prevention and treatment of mental disease or disorder   Human Learning and Memory   Imaging Techniques   Imaging, image processing   Neurodegeneration   Neurogenetics   Neuropharmacology   Neuropsychology   Psychiatry   Vision
 NETHATE: Network of Excellence of Training on HATE
 Development of an innovative method for diagnosis of Neonatal Encephalopathy
 Effects of Brain Training in Older Healthy Subjects
 The application of magnetic resonance imaging to the study of memory processes in young and older healthy adults, and older adults with mild cognitive impairment.
 Neuronal Coordination

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Details Date
Dementia and Neurodegeneration Network Ireland (DNNI) Multidisciplinary Consensus Panel since 2017
Reviewer for scientific journals and grant applications. since 2000
2015 Discover Science Night. 25-Sep-2015
2014 Discover Science Night. 26-Sep-2014
Co-Lead of Organizing Committee for workshop 'Neuroimaging in Dementia' May 2013
Co-Lead of Organizing Committee for workshop 'Application of neuroimaging in Alzheimer's disease' July 2013
Co-Lead of Organizing Committee for workshop 'Application of neuroimaging in Alzheimer's disease' September 2013
Co-Lead of Organizing Committee for workshop 'Introduction to theory and application of neuroimaging' September 2014
Co-Lead of Organizing Committee for workshop 'Neuroimaging - Theory and Practical Course' June 2015
Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
German Medium Medium Medium
Spanish Fluent Medium Fluent
Details Date From Date To
Society of Neuroscience (USA) 1998
German Society for Neuroscience 2001
Organization of Human Brain Mapping 2002
Neuroscience Ireland 2014
Chavanne AV, Paillère Martinot ML, Penttilä J, Grimmer Y, Conrod P, Stringaris A, van Noort B, Isensee C, Becker A, Banaschewski T, Bokde ALW, Desrivières S, Flor H, Grigis A, Garavan H, Gowland P, Heinz A, Brühl R, Nees F, Papadopoulos Orfanos D, Paus T, Poustka L, Hohmann S, Millenet S, Fröhner JH, Smolka MN, Walter H, Whelan R, Schumann G, Martinot JL, Artiges E, IMAGEN consortium., Anxiety onset in adolescents: a machine-learning prediction., Molecular psychiatry, 28, (2), 2023, p639-646 , Journal Article, PUBLISHED  DOI
Stepanous J, Munford L, Qualter P, Nees F, Elliott R, IMAGEN Consortium., Longitudinal Associations between Peer and Family Relationships, Emotional Symptoms, and Regional Brain Volume across Adolescence., Journal of youth and adolescence, 52, (4), 2023, p734-753 , Journal Article, PUBLISHED  DOI
Albaugh MD, Hudziak JJ, Spechler PA, Chaarani B, Lepage C, Jeon S, Rioux P, Evans AC, Banaschewski T, Bokde ALW, Desrivières S, Flor H, Gowland P, Heinz A, Ittermann B, Martinot JL, Martinot MP, Nees F, Orfanos DP, Poustka L, Millenet S, Fröhner JH, Smolka MN, Walter H, Whelan R, Schumann G, Potter AS, Garavan H, IMAGEN Consortium., Conduct problems are associated with accelerated thinning of emotion-related cortical regions in a community-based sample of adolescents., Psychiatry Res Neuroimaging, 330, 2023, p111614 , Journal Article, PUBLISHED  DOI
David López Pérez, Arun L.W. Bokde, Christian Kerskens, Complexity analysis of heartbeat-related signals in Brain MRI time series as a potential biomarker for ageing and cognitive performance, 232, (1), 2023, p123 - 133, Journal Article, PUBLISHED  DOI
Guldner S, Sarvasmaa AS, Lemaître H, Massicotte J, Vulser H, Miranda R, Bezivin-Frère P, Filippi I, Penttilä J, Banaschewski T, Barker GJ, Bokde AL, Bromberg U, Büchel C, Conrod PJ, Desrivières S, Flor H, Frouin V, Gallinat J, Garavan H, Gowland P, Heinz A, Nees F, Papadopoulos-Orfanos D, Smolka MN, Schumann G, Artiges E, Martinot MP, Martinot JL., Longitudinal associations between adolescent catch-up sleep, white-matter maturation and internalizing problems., Developmental cognitive neuroscience, 59, 2023, p101193 , Journal Article, PUBLISHED  DOI
Lopez S, Del Percio C, Lizio R, Noce G, Padovani A, Nobili F, Arnaldi D, Famà F, Moretti DV, Cagnin A, Koch G, Benussi A, Onofrj M, Borroni B, Soricelli A, Ferri R, Buttinelli C, Giubilei F, Güntekin B, Yener G, Stocchi F, Vacca L, Bonanni L, Babiloni C., Patients with Alzheimer's disease dementia show partially preserved parietal 'hubs' modeled from resting-state alpha electroencephalographic rhythms., Frontiers in aging neuroscience, 15, 2023, p780014 , Journal Article, PUBLISHED  DOI
Navarri X, Vosberg DE, Shin J, Richer L, Leonard G, Pike GB, Banaschewski T, Bokde ALW, Desrivières S, Flor H, Grigis A, Garavan H, Gowland P, Heinz A, Brühl R, Martinot JL, Martinot MP, Artiges E, Nees F, Orfanos DP, Poustka L, Hohmann S, Fröhner JH, Smolka MN, Vaidya N, Walter H, Whelan R, Schumann G, Pausova Z, Paus T., A biologically informed polygenic score of neuronal plasticity moderates the association between cognitive aptitudes and cortical thickness in adolescents., Developmental cognitive neuroscience, 60, 2023, p101232 , Journal Article, PUBLISHED  DOI
Kaiser A, Holz NE, Banaschewski T, Baumeister S, Bokde ALW, Desrivières S, Flor H, Fröhner JH, Grigis A, Garavan H, Gowland P, Heinz A, Ittermann B, Martinot JL, Martinot MP, Artiges E, Millenet S, Orfanos DP, Poustka L, Schwarz E, Smolka MN, Walter H, Whelan R, Schumann G, Brandeis D, Nees F, IMAGEN consortium., A DEVELOPMENTAL PERSPECTIVE ON FACETS OF IMPULSIVITY AND BRAIN ACTIVITY CORRELATES FROM ADOLESCENCE TO ADULTHOOD., Biological psychiatry : cognitive neuroscience and neuroimaging, 2022, Journal Article, PUBLISHED  DOI
Fröhner JH, Ripke S, Jurk S, Li SC, Banaschewski T, Bokde ALW, Quinlan EB, Desrivières S, Flor H, Grigis A, Garavan H, Heinz A, Brühl R, Martinot JL, Paillère Martinot ML, Artiges E, Nees F, Papadopoulos Orfanos D, Poustka L, Hohmann S, Walter H, Whelan R, Schumann G, Smolka MN, IMAGEN Consortium., Associations of delay discounting and drinking trajectories from ages 14 to 22., Alcoholism, clinical and experimental research, 2022, Journal Article, PUBLISHED  DOI
Xu J, Liu X, Li Q, Goldblatt R, Qin W, Liu F, Chu C, Luo Q, Ing A, Guo L, Liu N, Liu H, Huang C, Cheng J, Wang M, Geng Z, Zhu W, Zhang B, Liao W, Qiu S, Zhang H, Xu X, Yu Y, Gao B, Han T, Cui G, Chen F, Xian J, Li J, Zhang J, Zuo XN, Wang D, Shen W, Miao Y, Yuan F, Lui S, Zhang X, Xu K, Zhang L, Ye Z, Banaschewski T, Barker GJ, Bokde ALW, Flor H, Grigis A, Garavan H, Gowland P, Heinz A, Brühl R, Martinot JL, Artiges E, Nees F, Orfanos DP, Lemaitre H, Paus T, Poustka L, Robinson L, Hohmann S, Fröhner JH, Smolka MN, Walter H, Whelan R, Winterer J, Patrick K, Calhoun V, Li MJ, Liang M, Gong P, Barker ED, Clinton N, Marquand A, Yu L, Yu C, Schumann G, Schumann G, CHIMGEN, IMAGEN Consortia., Global urbanicity is associated with brain and behaviour in young people., Nature human behaviour, 6, (2), 2022, p279-293 , Journal Article, PUBLISHED  DOI
  

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Award Date
Sigma Gamma Tau, Member 1987
Arun Bokde investigates how large-scale brain networks function and how they are associated with both normal cognition, such as memory and attention, and breakdowns that lead to brain disorders. There are two populations of interest, young people and older people. Bokde uses functional magnetic resonance imaging to measure brain activation during visual perceptual tasks, as well as working memory tasks in persons with mild cognitive impairment, patients with Alzheimer's disease (AD), and healthy participants. These studies provide an understanding of how disease affects not only memory networks, but also perceptual processes in the brain. Recent findings were the basis of a new approach to testing AD-related drugs. In addition, Bokde has investigated the structural integrity of brain networks using diffusion imaging in combination with tractography in the limbic system, a network associated with memory function and profoundly affected in patients with AD. Bokde has also led an international project to develop training resources for the application of neuroimaging to the diagnostic process of AD patients, as well as developing resources for patients and their families to gain a better understanding of the disease. Bokde is co-PI (Ireland) for the the IMAGEN study, which is the first multicentre functional and structural genetic-neuroimaging study of a cohort of 2000 +14 year old adolescents. Cognitive, behavioural, clinical and neuroimaging data from the adolescents and their families and teachers have been gathered and the participants have been followed-up for 9 years - the third follow-up investigation is on-going. Bokde is investigating how stress modulates the development of brain networks, both within the thin cortical grey matter layer and the white matter regions that contain the 'cables' of the brain networks. The studies have been until now cross-sectional in nature and with new longitudinal data Bokde will start investigation of the interaction among stress, biological and genetic factors contributing to mental health disorders. He has close, long-standing collaborations with clinicians at St James's Hospital, Tallaght Hospital, and St Patrick's University Hospital. The collaborations enhance the communication and translation of research into the clinical context as well as feedback into research activities.