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Professor Daniel Bradley

Professor (Genetics)


Dan Bradley was brought up on a Northern Irish farm and after a degree in Genetics from Cambridge University and PhD in medical genetics from Trinity College Dublin he started to work on the genetics of each species present on that farm, including Irish humans, and has done for over 30 years. With his colleagues he has combined analysis of ancient and modern cattle to inform on the origins of these and other domesticates and pioneered the molecular genetic analysis of Irish populations. He holds a Personal Chair in Population Genetics in Trinity and was awarded the 2020 Royal Irish Academy Gold Medal in the Life Sciences
  ADMIXTURE   Ancient DNA analysis and origins of Irish mammals   ANIMAL DOMESTICATION   Archaeozoological genetics and the origins of cattle pastoralism   BOVINE EVOLUTION   BREED RELATIONSHIPS   CATTLE   CATTLE BOS-TAURUS   CONTROL REGION   Detection of recombination in mammalian mtDNA   DNA-SEQUENCE   DOMESTICATION   EQUUS CABALLUS   EUKARYOTIC GENOMES   EUROPEAN CATTLE   EUROPEAN POPULATIONS   EVOLUTION   FAMILY   FARMED   GENE   GENETIC CONSERVATION   GENETIC DIVERSITY   GENETIC VARIATION   HORSE   HUMAN DNA   INTROGRESSION   LINKAGE ANALYSIS   LINKAGE GROUP   LOCALIZATION   LOCI   MAP   MICROSATELLITE   MITOCHONDRIAL   MITOCHONDRIAL DNA   MTDNA   MUTATION   MYOTONIC-DYSTROPHY GENE   ORIGIN   ORIGINS   PIGS   POLYMORPHISMS   Population genetic signatures of selection in cattle and other domesticates   Population genetics, selection, structure and origins in Irish human populations   PREVALENCE   RELEASE   RYANODINE RECEPTOR GENE   SARCOPLASMIC-RETICULUM   SEQUENCE   SHEEP   Y chromosome diverisity and the genetic architecture of Irish surnames
 AncestralWeave: 1000 ancient genomes: gene-economy innovation in cattle, sheep and goat

Details Date
Member of a Wellcome Trust Panel responsible for the disbursement of research funds in Bioarchaeology
Appointed to Editorial Board of the international journal, Animal Genetics
Five times juror in the European Contest for Young Scientists
Member of the Royal Irish Academy Advisory Committee on Genetic Anthropology
Served as an expert consultant on genetic distance and biodiversity to the Food and Agriculture Organisation of the United Nations
Member, PHG Funded PI's and Researchers, All Researchers funded under Cycle 3 PRTLI - Programme for Human Genomics
Details Date From Date To
Member of International Society of Animal Genetics
former President of Irish Society of Human Genetics
Cooke N.P., Murray M., Cassidy L.M., Mattiangeli V., Okazaki K., Kasai K., Gakuhari T., Bradley D.G., Nakagome S., Genomic imputation of ancient Asian populations contrasts local adaptation in pre- and post-agricultural Japan, iScience, 27, (110050), 2024, Journal Article, PUBLISHED  DOI
Cooke N.P., Mattiangeli V., Cassidy L.M., Okazaki K., Kasai K., Bradley D.G., Gakuhari T., Nakagome S., Genomic insights into a tripartite ancestry in the Southern Ryukyu Islands, Evolutionary Huma Sciences, 5, 2023, pe23-, Journal Article, PUBLISHED  DOI
Cooke, N.P. and Mattiangeli, V. and Cassidy, L.M. and Okazaki, K. and Stokes, C.A. and Onbe, S. and Hatakeyama, S. and Machida, K. and Kasai, K. and Tomioka, N. and Matsumoto, A. and Ito, M. and Kojima, Y. and Bradley, D.G. and Gakuhari, T. and Nakagome, S., Ancient genomics reveals tripartite origins of Japanese populations, Science Advances, 7, (38), 2021, Notes: [cited By 46], Journal Article, PUBLISHED  DOI
Verdugo, M.P. and Mullin, V.E. and Scheu, A. and Mattiangeli, V. and Daly, K.G. and Maisano Delser, P. and Hare, A.J. and Burger, J. and Collins, M.J. and Kehati, R. and Hesse, P. and Fulton, D. and Sauer, E.W. and Mohaseb, F.A. and Davoudi, H. and Khazaeli, R. and Lhuillier, J. and Rapin, C. and Ebrahimi, S. and Khasanov, M. and Vahidi, S.M.F. and MacHugh, D.E. and ErtuÄ rul, O. and Koukouli-Chrysanthaki, C. and Sampson, A. and Kazantzis, G. and Kontopoulos, I. and Bulatovic, J. and StojanoviÄ , I. and Mikdad, A. and Benecke, N. and LinstÀdter, J. and Sablin, M. and Bendrey, R. and Gourichon, L. and Arbuckle, B.S. and Mashkour, M. and Orton, D. and Horwitz, L.K. and Teasdale, M.D. and Bradley, D.G., Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent, Science (New York, N.Y.), 365, (6449), 2019, p173-176 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Ring, S.C. and Purfield, D.C. and Good, M. and Breslin, P. and Ryan, E. and Blom, A. and Evans, R.D. and Doherty, M.L. and Bradley, D.G. and Berry, D.P., Variance components for bovine tuberculosis infection and multi-breed genome-wide association analysis using imputed whole genome sequence data, PLoS ONE, 14, (2), 2019, Notes: [cited By 1], Journal Article, PUBLISHED  TARA - Full Text  DOI
Frantz, L.A.F. and Haile, J. and Lin, A.T. and Scheu, A. and Geörg, C. and Benecke, N. and Alexander, M. and Linderholm, A. and Mullin, V.E. and Daly, K.G. and Battista, V.M. and Price, M. and Gron, K.J. and Alexandri, P. and Arbogast, R.-M. and Arbuckle, B. and BÇ lÇ Å escu, A. and Barnett, R. and Bartosiewicz, L. and Baryshnikov, G. and Bonsall, C. and BoriÄ , D. and BoroneanÅ£, A. and BulatoviÄ , J. and à akirlar, C. and Carretero, J.-M. and Chapman, J. and Church, M. and Crooijmans, R. and De Cupere, B. and Detry, C. and Dimitrijevic, V. and DumitraÅ cu, V. and Du Plessis, L. and Edwards, C.J. and Erek, C.M. and Erim-Ã-zdoǧan, A. and Ervynck, A. and Fulgione, D. and Gligor, M. and Götherström, A. and Gourichon, L. and Groenen, M.A.M. and Helmer, D. and Hongo, H. and Horwitz, L.K. and Irving-Pease, E.K. and Lebrasseur, O. and Lesur, J. and Malone, C. and Manaseryan, N. and Marciniak, A. and Martlew, H. and Mashkour, M. and Matthews, R. and Matuzeviciute, G.M. and Maziar, S. and Meijaard, E. and McGovern, T. and Megens, H.-J. and Miller, R. and Mohaseb, A.F. and Orschiedt, J. and Orton, D. and Papathanasiou, A. and Pearson, M.P. and Pinhasi, R. and RadmanoviÄ , D. and Ricaut, F.-X. and Richards, M. and Sabin, R. and Sarti, L. and Schier, W. and Sheikhi, S. and Stephan, E. and Stewart, J.R. and Stoddart, S. and Tagliacozzo, A. and TasiÄ , N. and Trantalidou, K. and Tresset, A. and Valdiosera, C. and Van Den Hurk, Y. and Van Poucke, S. and Vigne, J.-D. and Yanevich, A. and Zeeb-Lanz, A. and Triantafyllidis, A. and Gilbert, M.T.P. and Schibler, J. and Rowley-Conwy, P. and Zeder, M. and Peters, J. and Cucchi, T. and Bradley, D.G. and Dobney, K. and Burger, J. and Evin, A. and Girdland-Flink, L. and Larson, G., Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe, Proceedings of the National Academy of Sciences of the United States of America, 116, (35), 2019, p17231-17238 , Notes: [cited By 2], Journal Article, PUBLISHED  TARA - Full Text  DOI
Chen, N. and Cai, Y. and Chen, Q. and Li, R. and Wang, K. and Huang, Y. and Hu, S. and Huang, S. and Zhang, H. and Zheng, Z. and Song, W. and Ma, Z. and Ma, Y. and Dang, R. and Zhang, Z. and Xu, L. and Jia, Y. and Liu, S. and Yue, X. and Deng, W. and Zhang, X. and Sun, Z. and Lan, X. and Han, J. and Chen, H. and Bradley, D.G. and Jiang, Y. and Lei, C., Whole-genome resequencing reveals world-wide ancestry and adaptive introgression events of domesticated cattle in East Asia, Nature Communications, 9, (1), 2018, Notes: [cited By 4], Journal Article, PUBLISHED  TARA - Full Text  DOI
Daly, K.G. and Delser, P.M. and Mullin, V.E. and Scheu, A. and Mattiangeli, V. and Teasdale, M.D. and Hare, A.J. and Burger, J. and Verdugo, M.P. and Collins, M.J. and Kehati, R. and Erek, C.M. and Bar-Oz, G. and Pompanon, F. and Cumer, T. and à akırlar, C. and Mohaseb, A.F. and Decruyenaere, D. and Davoudi, H. and à evik, Ã-. and Rollefson, G. and Vigne, J.-D. and Khazaeli, R. and Fathi, H. and Doost, S.B. and Sorkhani, R.R. and Vahdati, A.A. and Sauer, E.W. and Kharanaghi, H.A. and Maziar, S. and Gasparian, B. and Pinhasi, R. and Martin, L. and Orton, D. and Arbuckle, B.S. and Benecke, N. and Manica, A. and Horwitz, L.K. and Mashkour, M. and Bradley, D.G., Ancient goat genomes reveal mosaic domestication in the Fertile Crescent, Science, 361, (6397), 2018, p85-88 , Notes: [cited By 3], Journal Article, PUBLISHED  DOI
Schroeder, H. and Sikora, M. and Gopalakrishnan, S. and Cassidy, L.M. and Delser, P.M. and Velasco, M.S. and Schraiber, J.G. and Rasmussen, S. and Homburger, J.R. and à vila-Arcos, M.C. and Allentoft, M.E. and Víctor Moreno-Mayar, J. and Renaud, G. and Gómez-Carballa, A. and Laffoon, J.E. and Hopkins, R.J.A. and Higham, T.F.G. and Carr, R.S. and Schaffer, W.C. and Day, J.S. and Hoogland, M. and Salas, A. and Bustamante, C.D. and Nielsen, R. and Bradley, D.G. and Hofman, C.L. and Willerslev, E., Origins and genetic legacies of the Caribbean Taino, Proceedings of the National Academy of Sciences of the United States of America, 115, (10), 2018, p2341-2346 , Notes: [cited By 3], Journal Article, PUBLISHED  TARA - Full Text  DOI
Byrne RP, Martiniano R, Cassidy LM, Carrigan M, Hellenthal G, Hardiman O, Bradley DG, McLaughlin RL, Insular Celtic population structure and genomic footprints of migration, PLOS Genetics, 14, 2018, pe1007152 , Journal Article, PUBLISHED  TARA - Full Text  DOI
  

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Oxen, Grolier Encyclopedia New Book of Knowledge, 2003, [Bradley DG ], Item in dictionary or encyclopaedia, etc, PUBLISHED
Bradley DG and Hill EW, Whats in a surname, Archaeology Ireland , 14, 2000, p22 - 23, Journal Article, PUBLISHED
Designing life: the role of inheritance in, editor(s)M. Jumker-Kenny , Designing life? Genetics, procreation and ethics, Aldershot, Ashgate Publishing Ltd, 1999, [Bradley DG], Book Chapter, PUBLISHED
Loftus R.T., D.E. MacHugh, P. Cunningham and D.G. Bradley, Animal domestication [letter], Science, 283, 1999, p329-30 , Journal Article, PUBLISHED
Loftus RT, D.G. Bradley, D.E. MacHugh, C.S. Troy, C.N. Meghen and E.P. Cunningham , Molecular genetics and the evolution of domesticated cattle, 8th World Conference on Animal Production, 1, 1998, pp144 - 145, Conference Paper, PUBLISHED
Meghen, C. N., Scott, C. S., Bradley, D. G., MacHugh, D. E., Loftus, R. T. and Cunningham, E. P. , DNA based traceability for the meat industry, 8th World Conference on Animal Production, 1998, pp774 - 775, Conference Paper, PUBLISHED
Bradley, DG and O'Sullivan, M., Tracing our ancient ancestors., Archaeology Ireland , 39, 1997, p18 - 20, Journal Article, PUBLISHED
McHugh, D. E., Loftus, R. T., Troy, C. S. and Bradley, D. G. , DNA Analysis and the origins and history of domesticated cattle, Archaeology of Southwest Asia (ASWA) conference, Budapest, 1996, Conference Paper, PUBLISHED
Bradley, D. G., Loftus, R. T., MacHugh, D. E. and Cunningham, P., The Molecular Evolution of Domestic cattle, Symposium on Mediterranean Animal Germplasm and Future Human Challenges, Salerno, 1996, Conference Paper, PUBLISHED
Cunningham, E. P., Loftus, R. T., MacHugh, D. E., Bradley, D. G., Molecular evolution of African, European and Asian Cattle, 21, 5th World Congress on Genetics Applied to Livestock Production, 1994, pp86 - 89, Conference Paper, PUBLISHED

  

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Award Date
TCD Fellowship 2000
CGIAR award for outstanding scientific article 2003
Member of the Royal Irish Academy 2009
Royal Irish Academy Gold Medal in the Life Sciences 2020
I have active research in: ancient genomic analysis of western European humans, particularly Irish archaeological remains; ancient genomes of cattle sheep and goat.