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Dr. Silvin Knight

Senior Research Fellow (Medical Gerontology)

 SILVIN.KNIGHT@tcd.ie

 


Biography

Dr Silvin Knight currently works as a Biostatistician and Senior Research Fellow at The Irish Longitudinal Study on Ageing (TILDA), TCD. His current research interests include quantitative modelling of haemodynamics and autoregulation (measured using Near-infrared Spectroscopy (NIRS), Finometer, and Arterial Spin Labelling (ASL) MRI), as well as developing data-driven and machine learning approaches for the analysis of these neurocardiovascular networks. Prior to joining TILDA, Silvin's research was largely focused on developing model systems and methodologies for improving / characterising the accuracy and precision of a number of quantitative MRI and ultrasound imaging techniques. Silvin completed his PhD at Trinity College Dublin in 2018 (funded by a four year research scholarship from the Irish Cancer Society), which was focused on improving the sensitivity and specificity of dynamic contrast enhanced (DCE) MRI for the detection of prostate cancer. He received his BSc in Physics (with Medical Physics and Bioengineering) from Dublin Institute of Technology in 2013, graduating with first-class honours. Prior to the career change into physics / biomedical engineering in 2010, he worked for over 10 years in the design / advertising industry as a graphic designer / project manager.

Representations

Details Date
Associate Editor for The IEEE Journal of Translational Engineering in Health and Medicine (JTEHM) 1/1/2022
Silvin Knight, Eoin Duggan, Feng Xue, Roman Romero-Ortuno, Investigating Skeletal Muscle Pump Function Using Thigh EMG, Thigh NIRS, And Stroke Volume Data In The FRAILMatics Physiological Cohort, Age and Ageing, IGS 2024, Ireland, 53, (Issue Supplement_4), Oxford Academic, 2024, Conference Paper, PUBLISHED  DOI  URL
Toni Mockler, Silvin Knight, Peter Hartley, Emma Connolly, Feng Xue, Eoin Duggan, Roman Romero-Ortuno, Relationship Between Lifestyle Factors and Accelerometery Based Motion Capture Analysis During An Active Stand In Healthy Older Adults, Age and Ageing, IGS 2024, Ireland, 53, (Supplement_4), 2024, Conference Paper, PUBLISHED  DOI  URL
Feng Xue, Silvin Knight, Emma Connolly, Morgana Afonso Shirsath, Louise Newman, Eoin Duggan, Rose Anne Kenny and Roman Romero-Ortuno, Functional Clustering of Systolic Blood Pressure and Frontal Brain Oxygenation During an Active Stand Test in The Irish Longitudinal Study on Ageing (TILDA): A Comparison of Tissue Saturation Index Versus Absolute Oxygenated Hemoglobin Concentration Approaches, IEEE SENSORS JOURNAL, 2024, Journal Article, PUBLISHED  DOI  URL
A., Shirsath M., O'Connor J.D., Boyle R., Newman L., Knight S.P., Hernandez B., Whelan R., Meaney J.F., Kenny R.A., Slower speed of blood pressure recovery after standing is associated with accelerated brain aging: Evidence from The Irish Longitudinal Study on Ageing (TILDA), Cerebral Circulation - Cognition and Behavior, 6, 2024, Journal Article, PUBLISHED  DOI  DOI
Feng Xue, Silvin P. Knight, Emma Connolly, Aisling M. O"Halloran, Morgana Afonso Shirsath, Louise Newman, Eoin Duggan, Rose Anne Kenny, Roman Romero-Ortuno, Were Frailty Identification Criteria Created Equal? A Comparative Case Study on Continuous Non-Invasively Collected Neurocardiovascular Signals during an Active Standing Test in the Irish Longitudinal Study on Ageing (TILDA), Sensors, 2024, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Simon C, Bolton DAE, Meaney JF, Kenny RA, Simon VA, De Looze C, Knight S, Ruddy KL., White matter fibre density in the brain's inhibitory control network is associated with falling in low activity older adults., The European journal of neuroscience, 2024, Journal Article, PUBLISHED  DOI
Emma Connolly, Silvin P. Knight, Eoin Duggan, Siobhan Scarlett, Louise Newman, Mark Cahill, Rose Anne Kenny, Sarah L. Doyle, Roman Romero-Ortuno, Cardiovascular autonomic function and progression of age-related macular degeneration in The Irish Longitudinal Study of Ageing (TILDA), Investigative Ophthalmology & Visual Science, 2024, Journal Article, PUBLISHED  TARA - Full Text  DOI
Hu J, Craig MS, Knight SP, De Looze C, Meaney JF, Kenny RA, Chen X, Chappell MA, Regional changes in cerebral perfusion with age when accounting for changes in gray-matter volume., Magnetic resonance in medicine, 2024, Journal Article, PUBLISHED  DOI
De Looze C, Demnitz N, Knight S, Carey D, Meaney J, Kenny RA, McCrory C., Examining the impact of socio-economic position (SEP) across the life course on cognitive function and brain structure in healthy ageing., The journals of gerontology. Series A, Biological sciences and medical sciences, 2023, pglad068 , Journal Article, PUBLISHED  DOI
Knight SP, Ward M, Duggan E, Xue F, Kenny RA, Romero-Ortuno R., Evaluation of a 3-Item Health Index in Predicting Mortality Risk: A 12-Year Follow-Up Study, Diagnostics, 2023, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
  

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