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Dr. Silvin Knight

Senior Research Fellow (Medical Gerontology)

 


Dr. Silvin Knight currently works as a Senior Research Fellow within the FRAILMatics research programme and The Irish Longitudinal Study on Ageing (TILDA), TCD. His current research interests include quantitative modelling of haemodynamics and autoregulation (measured using Near-infrared Spectroscopy (NIRS), Finometer, and Arterial Spin Labelling (ASL) MRI), as well as developing data-driven and machine learning approaches for the analysis of these neurocardiovascular networks. Prior to joining TILDA, Silvin's research was largely focused on developing model systems and methodologies for improving / characterising the accuracy and precision of a number of quantitative MRI and ultrasound imaging techniques. Silvin completed his PhD at Trinity College Dublin in 2018 (funded by a four year research scholarship from the Irish Cancer Society), which was focused on improving the sensitivity and specificity of dynamic contrast enhanced (DCE) MRI for the detection of prostate cancer. He received his BSc in Physics (with Medical Physics and Bioengineering) from Dublin Institute of Technology in 2013, graduating with first-class honours. Prior to the career change into physics / biomedical engineering in 2010, he worked for over 10 years in the design / advertising industry as a graphic designer / project manager.
Gutiérrez-Zúñiga R, Davis J.R., Boyle R, De Looze C, Meaney J, Whelan R, Kenny R.A., Knight S.P., Romero-Ortuño R, Brain connectivity in frailty: insights from The Irish Longitudinal Study on Ageing (TILDA), Neurobiology of Aging, 2023, Journal Article, PUBLISHED  DOI  URL
SP Knight, J Davis, E Duggan, RA Kenny, R Romero-Ortuno, ASSOCIATIONS BETWEEN CARDIOVASCULAR SIGNAL ENTROPY AND FUTURE FALLS, SYNCOPE, AND FEAR OF FALLING, Age and Ageing, Annual and Scientific Meeting of the Irish Gerontological Society 2022: New Frontiers in Gerontology, 2022, 51, (Supplement_3), 2022, Conference Paper, PUBLISHED  DOI  URL
E Duggan, CH Murphy, SP Knight, JRC Davis, AM O'Halloran, RA Kenny, R Romero-Ortuno, INVESTIGATING THE RELATIONSHIP BETWEEN PROBABLE SARCOPENIA AND ORTHOSTATIC HYPOTENSION: FINDINGS FROM THE IRISH LONGITUDINAL STUDY ON AGEING, Age and Ageing, Annual and Scientific Meeting of the Irish Gerontological Society 2022: New Frontiers in Gerontology, 2022, 51, 2022, Conference Paper, PUBLISHED  DOI  URL
JRC Davis, R Boyle, SP Knight, R Romero-Ortuño, RG Zúñiga, GRIP STRENGTH, ONLY A PHYSICAL TASK? ASSOCIATIONS BETWEEN RESTING-STATE BRAIN CONNECTIVITY AND GRIP STRENGTH, Age and Ageing, Annual and Scientific Meeting of the Irish Gerontological Society 2022: New Frontiers in Gerontology, 2022, 51, 2022, Conference Paper, PUBLISHED  DOI  URL
C Murphy, E Duggan, S Knight, J Davis, RG Zuniga, E Connolly, RA Kenny, S McCarthy, R Romero-Ortuno, RELATIONSHIP BETWEEN SERUM CAROTENOID CONCENTRATIONS AND FRAILTY, PROBABLE SARCOPENIA, AND PHYSICAL FUNCTION IN THE IRISH LONGITUDINAL STUDY ON AGEING (TILDA), Age and Ageing, Annual and Scientific Meeting of the Irish Gerontological Society 2022: New Frontiers in Gerontology, 2022, 51, 2022, Conference Paper, PUBLISHED  DOI  URL
Silvin P. Knight, Mark Ward, Louise Newman, James Davis, Eoin Duggan, Rose Anne Kenny, Roman Romero-Ortuno, Cardiovascular signal entropy predicts all-cause mortality: evidence from The Irish Longitudinal Study on Ageing (TILDA), Entropy (Basel), 2022, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Winning L., Naseer A., De Looze C., Knight S.P., Kenny R.A., O'Connell B., Tooth loss and cognitive decline in community dwelling older Irish adults: A cross-sectional cohort study, Journal of Dentistry, 119, 2022, Journal Article, PUBLISHED  TARA - Full Text  DOI
Andrea J. Doyle, Dervil Cody, Silvin Knight, Deirdre M. King, Francis J. Sullivan, Jacinta E. Browne, Contrast-Specific Spherical Lesion Phantoms and Ancillary Analysis Software for the Objective Evaluation of Transrectal Ultrasound System Contrast Detectability, Ultrasound in Medicine & Biology, 2022, Journal Article, PUBLISHED  DOI  URL
Rossella Rizzo, Silvin P. Knight, James R. C. Davis, Louise Newman, Eoin Duggan, Rose Anne Kenny, Roman Romero-Ortuno, Longitudinal study on Sustained Attention to Response Task (SART): clustering approach for mobility and cognitive decline, Geriatrics (Basel), 2022, Journal Article, PUBLISHED  TARA - Full Text  DOI
Eoin Duggan, Caoileann H. Murphy, Silvin P. Knight, James R.C. Davis, Aisling M. O'Halloran, Rose Anne Kenny, Roman Romero-Ortuno, Differential Associations Between Two Markers of Probable Sarcopenia and Continuous Orthostatic Hemodynamics in The Irish Longitudinal Study on Ageing, Journal of Gerontology: Medical Sciences, 2022, Journal Article, PUBLISHED  TARA - Full Text  DOI
  

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