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Dr. Sean Kennelly

Clinical Associate Professor (Medical Gerontology)

 sekennel@tcd.ie

 

Clinical Associate Professor (Trinity Inst. of Neurosciences (TCIN))


Biography

Professor Sean Kennelly MB BCh BAO PhD FRCP(Lond) FRCPI is a consultant physician in geriatric and stroke medicine in Tallaght University Hospital (TUH) and Clinical Associate Professor of Medical Gerontology in Trinity College. He is Director of the Institute for Memory and Cognition, and the Cognitive Clinical Trials Unit in Tallaght University Hospital, Dublin. He is clinical director of the National Intellectual Disability Memory Service in TUH. He is co-lead investigator on HRB-funded Dementia Trials Ireland, a national clinical trials network, and is principle investigator on HRB-funded of Dementia Research Network Ireland (DRNI). A fellow of the Royal College of Physicians in London & Ireland, he has extensively published in his main research areas of Ageing, brain health, dementia, and Inflammaging. He has served as chief and principal investigator on several international clinical trials in early-stage Alzheimer's disease. He is principle investigator and lead-clinical advisor on several industry collaborations investigating novel applications of digital gait and speech biomarkers in detection of cognitive decline. He is a member of the clinical and research advisory panel for the Alzheimer's Society Ireland and a principal investigator in the Trinity College Institute of Neuroscience. He is a faculty member for the Global Brain Health Institute in Trinity College Dublin. He is a member of the clinical and research advisory panel for the Alzheimer's Society of Ireland. He is on several clinical and service advisory committees for the national clinical program for older people and the national dementia office. He is a member of the national dementia strategy monitoring group within the department of health. He served as associate dean of higher specialty training in general internal medicine in the Royal College of Physicians of Ireland 2017-2021.

Research Tags

  Ageing, Older People and Healthcare   Ageing, stroke, dementia   ALZHEIMER'S DEMENTIA   BRAIN AGEING   Brain Health in Ageing   DEMENTIA   DEMENTIA SERVICES   EARLY ONSET DEMENTIA   LEWY BODY DEMENTIA   Older Adults - ageing in place, dementia, aging and technolo   Positive Ageing

Research Projects

 Dementia Research Network Ireland
 Dementia Trials Ireland
 TIDE-AD: Translating Inflammatory Biomarkers to Predict Disease Progression & Adverse Events in Alzheimer Disease
 Supporting Tallaght University Hospital's (TUH) Integrated Care for Older Persons Service: Identifying the common housing hazards affecting older people in South Dublin
 Including best practices and the voices of experience in developing post-diagnostic dementia support guidelines for people with an intellectual disability

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Languages

Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
Helena Dolphin, Adam H Dyer, Laura Morrison, Susan D Shenkin, Tomas Welsh, Sean P Kennelly, New horizons in the diagnosis and management of Alzheimer"s Disease in older adults, Age and Ageing, 53, (2), 2024, Journal Article, PUBLISHED  DOI
Donnell DO, Romero-Ortuno R, Kennelly SP, O'Neill D, Donoghue PO, Lavan A, Cunningham C, McElwaine P, Kenny RA, Briggs R., The 'Bermuda Triangle' of orthostatic hypotension, cognitive impairment and reduced mobility: prospective associations with falls and fractures in The Irish Longitudinal Study on Ageing. , Age and Ageing, 52, (2), 2023, pafad005 , Journal Article, PUBLISHED  DOI  URL
Murphy C, Dyer AH, Lawlor B, Kennelly SP, for the NILVAD study group, What is the impact of ongoing statin use on cognitive decline and dementia progression in older adults with mild-moderate Alzheimer disease?, PLoS ONE, 2023, Journal Article, PUBLISHED  DOI
Hu Z, Ondrejcak T, Yu P, Zhang Y, Yang Y, Klyubin I, Rowan MJ, Kennelly SP, Hu NW, Do tau-synaptic long-term depression interactions in the hippocampus play a pivotal role in the progression of Alzheimer's disease?, Neural Regeneration Research, 18, (6), 2023, p1213-1219 , Journal Article, PUBLISHED  DOI
McGlinchey, E., Daly, L., Allen, A., Dennehy, H., Buttery, N., Corr, C., McCallion, P., Kennelly, S., Dunne, P., McCarron, M., Developing Best Practice Guidelines for Post-Diagnostic Dementia Support for People with an Intellectual Disability, 33rd Alzheimer Europe Conference, Helsinki, 16-18 October 2023, 2023, Oral Presentation, PUBLISHED
Dyer AH, Noonan C, McElheron M, Batten I, Reddy C, Connolly E, Pierpoint R, Murray C, Leonard A, Higgins C, Reilly P, Boran G, Phelan T, McCormack W, O'Neill D, Fallon A, Brady G, O'Farrelly C, Bourke NM, Kennelly SP., Previous SARS-CoV-2 Infection, Age, and Frailty Are Associated With 6-Month Vaccine-Induced Anti-Spike Antibody Titer in Nursing Home Residents, Journal of the American Medical Directors Association, 2022, Journal Article, PUBLISHED  DOI  URL
Dennehy H., Allen A.P., McGlinchey E., Buttery N., Garcia-Dominguez L., Chansler R., Corr C., Dunne P., Kennelly S., Daly L. McCallion P. and McCarron M., A scoping review of post-diagnostic dementia supports for people with intellectual disability, Aging and Mental Health, 2022, Journal Article, PUBLISHED  URL
Grey T, Xidous D, O'Donoghue J, Kennelly S, O'Neill D, Universal Design for Improving Quality of Life and Enhancing COVID-19 Infection Control in Existing Residential Care Settings for Older People: Research Report, Dublin, Centre for Excellence in Universal Design, 2022, p1 - 110, Report, PUBLISHED  URL
Grey T, Xidous D, O'Donoghue J, Kennelly S, O'Neill D, Improving Quality of Life and Enhancing COVID-19 Infection Control in Existing Residential Care Settings for Older People: Universal Design Guidelines, Dublin, Centre for Excellence in Universal Design, 2022, p1 - 44, Report, PUBLISHED  URL
Kennelly SP, Dyer AH, Noonan C, Kennelly SM, Martin A, O'Neill D, Fallon A, Asymptomatic carriage rates and case-fatality of SARS-CoV-2 infection in residents and staff in Irish nursing homes, Age and Ageing, 50, (1), 2021, p49 - 54, Journal Article, PUBLISHED  DOI  URL
  

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McCarron, M., Daly, L., McCallion, P., Allen, A.P., Buttery, N., Dennehy, H., Kennelly, S., Corr, C., Dunne, P., McGlinchey, E., Post-Diagnostic Dementia Support Guidelines for People with an Intellectual Disability, 17, Trinity College Dublin, March, 2024, Report, PUBLISHED
McCarron, M., Allen, A.P., Buttery, N., Dennehy, H., Kennelly, S., Corr, C., Dunne, P., Daly, L., McCallion P., McGlinchey, E., Voices of Experience: Building Post-Diagnostic Dementia Support Guidelines for People with an Intellectual Disability. Brief Report, 5, Trinity College Dublin, January, 2024, Report, PUBLISHED

  

Research Interests

Description Of Research Interests

Dementia Prevention Clinical Trials in Dementia Brain Health Digital Biomarkers of ageing and cognitive decline Dementia in Down Syndrome Changes in Inflammatory System and Vaccine responses within the context of ageing and frailty. Biology of Ageing research