Skip to main content

Trinity College Dublin, The University of Dublin

Menu Search


Trinity College Dublin By using this website you consent to the use of cookies in accordance with the Trinity cookie policy. For more information on cookies see our cookie policy.

      
Profile Photo

Dr. Mark Ward

Medical Scientist (Histopathology)

 mward4@tcd.ie

 


Biography

Dr. Mark Ward graduated from Trinity College Dublin in 2012 with a BA (Mod.) in Biochemistry. Following this, he completed a PhD in 2016 in the Department of Pharmacology and Therapeutics in Trinity College Dublin investigating the role of Protein Phosphatase 2A (PP2A) and its endogenous inhibitors in the regulation of matrix metalloproteinases and inflammation in liver cancer. His current research focuses on the area of "Liquid Biopsy" and the isolation and molecular characterisation of rare circulating tumour cells (CTCs) from breast and ovarian cancer patients. His research interests also include the role platelets and immune cells play in cancer metastasis as well as thrombosis in gynaecological cancers. https://orcid.org/0000-0002-9356-7246

Research Tags

  BREAST CANCER   cancer inflammation   Circulating Tumour Cells   ctDNA   Extracellular vesicles (EVs)   Gynaecological cancer   INFLAMMATION   Inflammation and coagulation syndromes   Liquid Biopsy   METASTASIS   NEUTROPHILS   Ovarian Cancer   OVARIAN VEIN-THROMBOSIS   PLATELETS   THROMBIN

Memberships

Membership of Professional Institutions, Associations, Societies

Details Date From Date To
European Association for Cancer Research 2018 Present
The Irish Society for Gynaecological Oncology (ISGO) 2016 2023
Bates M, Mohamed BM, Ward MP, Kelly TE, O'Connor R, Malone V, Brooks R, Brooks D, Selemidis S, Martin C, O'Toole S, O'Leary JJ., Circulating tumour cells: The Good, the Bad and the Ugly., Biochim Biophys Acta Rev Cancer, 1878, (2), 2023, p188863 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Mohamed BM, Ward MP, Bates M, Spillane CD, Kelly T, Martin C, Gallagher M, Heffernan S, Norris L, Kennedy J, Saadeh FA, Gleeson N, Brooks DA, Brooks RD, Selemidis S, O'Toole S, O'Leary JJ., Ex vivo expansion of circulating tumour cells (CTCs)., Scientific reports, 13, (1), 2023, p3704 - 3704, Journal Article, PUBLISHED  DOI
Logan JM, Hopkins AM, Martini C, Sorvina A, Tewari P, Prabhakaran S, Huzzell C, Johnson IRD, Hickey SM, Ung BS, Lazniewska J, Brooks RD, Moore CR, Caruso MC, Karageorgos L, Martin CM, O'Toole S, Bogue Edgerton L, Ward MP, Bates M, Selemidis S, Esterman A, Heffernan S, Keegan H, Ní Mhaolcatha S, O'Connor R, Malone V, Carter M, Ryan K, Clarke A, Brady N, Klebe S, Samaratunga H, Delahunt B, Sorich MJ, Moretti K, Butler LM, O'Leary JJ, Brooks DA., Prediction of Prostate Cancer Biochemical and Clinical Recurrence Is Improved by IHC-Assisted Grading Using Appl1, Sortilin and Syndecan-1., Cancers, 15, (12), 2023, p3215 , Journal Article, PUBLISHED  DOI
Lazniewska J, Li KL, Johnson IRD, Sorvina A, Logan JM, Martini C, Moore C, Ung BS, Karageorgos L, Hickey SM, Prabhakaran S, Heatlie JK, Brooks RD, Huzzell C, Warnock NI, Ward MP, Mohammed B, Tewari P, Martin C, O'Toole S, Edgerton LB, Bates M, Moretti P, Pitson SM, Selemidis S, Butler LM, O'Leary JJ, Brooks DA., Dynamic interplay between sortilin and syndecan-1 contributes to prostate cancer progression., Scientific reports, 13, (1), 2023, p13489 , Journal Article, PUBLISHED  DOI
Ward MP, Ibrahim E, O'Toole S, Gleeson N, Abu Saadeh F, O'Donnell D, Norris LA, Thrombomodulin as a marker for VTE following neoadjuvant chemotherapy, Thrombosis Research, International Congress on Issues in Thrombosis in Cancer , Bergamo, Italy, May 2022, 213, ((6) Supplement 2), Elsevier, 2022, ppS13 - S14, Conference Paper, PUBLISHED  URL
Ward MP, O'Toole SA, Abu Saadeh F, Marchocki Z, Ibrahim EM, Martin F, Gleeon N, O'leary JJ, Norris LA, Mechanisms of cancer associated thrombosis in gynaecological cancer patients- tumour or treatment effect?, Research Practice in Thrombosis and Haemostasis, International Society for Thrombosis and Haemostasis, London, July 2022, 6, (Supplement 2), Wiley, 2022, ppPB0752 - PB0752, Conference Paper, PUBLISHED  URL
Ward MP, Lochrin SE, Ovarere C, O'Gorman C, Kane LE, Mohamed BM, Bates M, Kelly TE, O'Connor R, Kennedy J, Cadoo K, Kamran W, Beirne J, Abu Saadeh F, Martin CM, Norris LA, O'Toole SA, O'leary JJ, Platelets and immune call cloaking of circulating tumour cells in breast and ovarian cancer, Research Practice in Thrombosis and Haemostasis, International Society for Thrombosis and Haemostasis, London, July 2022, 6, ((supplement 2)), Wiley, 2022, ppPB0931 - PB0931, Conference Paper, PUBLISHED  URL
Martini C, Logan JM, Sorvina A, Gordon C, Beck AR, S-Y Ung B, Caruso MC, Moore C, Hocking A, Johnson IRD, Li KL, Karageorgos L, Hopkins AM, Esterman AJ, Huzzell C, Brooks RD, Lazniewska J, Hickey SM, Bader C, Parkinson-Lawrence E, Weigert R, Sorich MJ, Tewari P, Martin C, O'Toole S, Bates M, Ward M, Mohammed B, Keegan H, Watson W, Prendergast S, Heffernan S, NiMhaolcatha S, O'Connor R, Malone V, Carter M, Ryan K, Brady N, Clarke A, Sokol F, Prabhakaran S, Stahl J, Klebe S, Samaratunga H, Delahunt B, Selemidis S, Moretti KL, Butler LM, O'Leary JJ, Brooks DA., Aberrant protein expression of Appl1, Sortilin and Syndecan-1 during the biological progression of prostate cancer., Pathology, 2022, pS0031-3025(22)00226-4 , Journal Article, PUBLISHED  DOI
Mark P Ward, Mark Bates, Bashir Mohamed, Tanya Kelly, Roisin O'Connor, Robert Brooks, Doug Brooks, Stavros Selemidis, Celine Ovaere, Jane Tully, Patrick Maguire, Catherine O'Gorman, Waseem Kamran, James Beirne, Feras Saadeh, Noreen Gleeson, Lucy Norris, Cara Martin, Sharon O'Toole, John O'Leary, Isolation and characterisation of circulating tumour cells from ovarian cancer patients, LABORATORY INVESTIGATION, March 2022, 102, (SUPPL 1), SPRINGER NATURE, 2022, Poster, PUBLISHED  DOI
Ward, M.P., Kane, L.E., Norris, L.A et al. , Platelets, immune cells and the coagulation cascade; friend or foe of the circulating tumour cell?, Molecular Cancer, 20, 2021, p59-, Journal Article, PUBLISHED  DOI
  

Page 1 of 3
Mark P. Ward, Bashir M. Mohamed, Laura Kane, Mark Bates, Janina Berghoff, Cathy L. Spillane, Tanya Kelly, John Kennedy, Feras A. Saadeh, Karsten Hokamp, Noreen Gleeson, Orla Sheils, Cara Martin, Michael Gallagher, Sean Hannify, Eric P. Dixon, Sharon A. O'Toole and John J. O'Leary, Influence of platelets and neutrophils on circulating tumour cells, AACR Annual Meeting , Philadelphia, PA, 2020; April 27-28, 80, (16), American Association for Cancer Research, 2020, Poster, PUBLISHED

  

Research Interests

Description Of Research Interests

Liquid Biopsy (CTCs, ctDNA, EVs) in cancer, cancer associated thrombosis and platelet/immune cell mediated cancer metastasis.