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Professor Rustom Manecksha

Clinical Associate Professor (Surgery)
      
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Professor Rustom Manecksha

Clinical Associate Professor (Surgery)

 Rustom.Manecksha@tcd.ie

 


A graduate from the School of Medicine, University College Dublin in 2000, I was awarded an M.D. from Trinity College Dublin for work on prostate cancer progression to androgen independence. I completed a 2-year Endourology Fellowship at the Austin Hospital in Melbourne, Australia. I was the recipient of the Anthony Walsh/Ipsen/RCSI Travelling Fellowship, the Ethicon Travelling Fellowship and the RCSI Travelling Fellowship. On completion of my clinical fellowship in 2013, I returned to a locum consultant position in St. James's Hospital running the National Cancer Control Programme's rapid access prostate clinic. I was subsequently appointed Consultant Urological Surgeon in St. James's and Tallaght Hospitals, Dublin in 2014. My special interests are in endourology, kidney stone disease, BPH, minimal access renal surgery and prostate cancer. I have an active clinical research profile, with national and international collaborations as well as links with the Institute of Molecular Medicine, Trinity Centre for Health Sciences.
  Benign prostate surgery   CALCULI   Endoluminal endourology   Endourology   KIDNEY CALCULI   LARGE RENAL CALCULI   PROSTATE   PROSTATE CANCER   RENAL CALCULI   STAGHORN CALCULI   TRANS-URETHRAL PROSTATECTOMY   URETERAL CALCULI
Project Title
 PERSIST Study
From
01/01/2017
To
Summary
Randomized control trial to compare the efficacy and safety of percutaneous nephrostomy with retrograde ureteric stenting for emergency renal decompression in cases of obstruction and sepsis associated with ureteric calculi. The obstructed kidney in the setting of urosepsis is a urological emergency. Stone manipulation in the setting of active, untreated infection with concomitant urinary tract obstruction can lead to life-threatening sepsis. Therefore, urgent decompression of the collecting system is warranted. There are two options for urgent decompression of an obstructed collecting system: Image-guided percutaneous nephrostomy tube placement Cystoscopic retrograde placement of a ureteric stent This strategy allows drainage of infected urine and penetration of antibiotics to the affected renal unit. Definitive stone manipulation should be delayed until the infection is cleared following an appropriate course of antimicrobial therapy. Both the European Association of Urology (EAU) and the American Urological Association (AUA) provide guidelines for management of an obstructed kidney. Both organisations provide evidence-based statements of the highest recommendation that urgent decompression of the kidney is mandated in the setting of sepsis. However, neither organisation recommend one decompression modality over the other. There is a lack of high quality up-to-date evidence to support a consensus view that one method of decompression is superior to the other. This study aims to determine the most effective method of renal decompression in cases of obstruction and sepsis associated with ureteric calculi.
Funding Agency
Self funded
Project Type
RCT
Project Title
 MaSH Study
From
2015
To
2017
Summary
The Men and Sexual Health Prostate Cancer Study is a joint Cancer Council Queensland and Griffith University Queensland project, led by Professor Suzanne Chambers of Griffith University, and coordinated in Ireland by Mr Rustom Manecksha, Consultant Urological Surgeon at St James's and Tallaght Hospitals. This online study will assess concerns about sexual health and what contributes to a man's decision to seek support for their sexual concerns. Part of the purpose of this study is to allow researchers/clinicians to better understand the needs of men so that they can then devise various programmes and resource their rehabilitation accordingly.
Funding Agency
Cancer Council Queensland
Project Title
 Risks factors for Flexible Ureteroscope Damage
From
July 2017
To
July 2019
Summary
Prospective study of risk factors that increase the likelihood of damage to reusable flexible ureteroscopes. A collaborative study with The Austin Hospital, Melbourne
Funding Agency
no funding
Project Type
Prospective

Details Date
Established the Irish Society of Urology website 2014-2015
Established and moderate the Irish Society of Urology Twitter page. 2014 - present
Developing the urology curriculum for undergraduate medical students on behalf of the Irish Society of Urology. 2019
Journal Reviewer for BJU International 2018
Journal Reviewer for Journal of Endourology 2017
Journal Reviewer for Irish Journal of Medical Science 2018
Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
Malay Fluent Fluent Fluent
Details Date From Date To
Endourological Society 2013 present
British Association of Urology 2003 present
British Association of Urology (Subsection of Endourology) 2013 present
European Association of Urology 2003 present
Irish Society of Urology 2003 present
Americal Urological Association 2005 present
O'Reilly E, Tuzova AV, Walsh AL, Russell NM, O'Brien O, Kelly S, Dhomhnallain ON, DeBarra L, Dale CM, Brugman R, Clarke G, Schmidt O, O'Meachair S, Patil D, Pellegrini KL, Fleshner N, Garcia J, Zhao F, Finn S, Mills R, Hanna MY, Hurst R, McEvoy E, Gallagher WM, Manecksha RP, Cooper CS, Brewer DS, Bapat B, Sanda MG, Clark J, Perry AS., epiCaPture: A Urine DNA Methylation Test for Early Detection of Aggressive Prostate Cancer., JCO Precis Oncol, 2019, 2019, Journal Article, PUBLISHED  DOI
Bhatt NR, Mohammed W, Wagner P, Elkhalifa A, Flynn RJ, Thomas AZ, Manecksha RP., Urinary catheters in the emergency department: a prospective audit to improve quality control., Central European journal of urology, 72, (1), 2019, p62-65 , Journal Article, PUBLISHED  DOI
Redmond EJ, Manecksha RP., Re: Intravesical Gentamicin Treatment for Recurrent Urinary Tract Infections Caused by Multidrug Resistant Bacteria., The Journal of urology, 2019, p101097JU0000000000000364 , Journal Article, PUBLISHED  DOI
Lynch OE, Redmond EJ, Inder MS, Flynn RJ, Thomas AZ, Smyth LG, Manecksha RP., The utility of stent on strings in clinical practice., Ir J Med Sci, 2019, Journal Article, PUBLISHED  DOI
S Inder, M Bates, N Ni Labhrai, N McDermott, J Schneider, G Erdmann, T Jamerson, AN Flores, A Prina-Mello, P Thirion, PR Manecksha, D Cormican, S Finn, T Lynch, L Marignol, Multiplex profiling identifies clinically relevant signalling proteins in an isogenic prostate cancer model of radioresistance, Scientific Reports, 9, 2019, p1 - 12, Journal Article, PUBLISHED  TARA - Full Text  DOI
Yap LC, Lynch TH, Manecksha RP., MRI for clinically suspected prostate cancer-the disparity between private and public sectors., Ir J Med Sci, 2019, Journal Article, PUBLISHED  DOI
Roche EC, Redmond EJ, Yap LC, Manecksha RP., Seasonal Variation in the Frequency of Presentation with Acute Ureteral Colic and Its Association with Meteorologic Factors., Journal of endourology, 2019, Journal Article, PUBLISHED  DOI
Bhatt NR, Merchant R, Davis NF, Leonard M, O'Daly BJ, Manecksha RP, Quinlan JF, Incidence and immediate management of genitourinary injuries in pelvic and acetabular trauma: a 10-year retrospective study., BJU international, 2018, Journal Article, PUBLISHED
Rosie Colgan, Nikita Rajiv Bhatt, Rajiv Merchant, Niall Davis, Michael Leonard, Brendan O"Daly, Rustom Manecksha, John Quinlan, AB115. 128. A 10-year review of genito-urinary injuries in pelvic and acetabular trauma, Mesentery and Peritoneum, 2, (1), 2018, pAB115--AB115 , Journal Article, PUBLISHED
D'Arcy F, Yip CL, Manya K, McGivern P, Manecksha RP, Bolton D, Sengupta S, Prospective randomised controlled trial of written supplement to verbal communication of results to patients at the time of flexible cystoscopy., World journal of urology, 2018, Journal Article, PUBLISHED
  

Page 1 of 8
Nikita R. Bhatt, Rustom P. Manecksha, Robert J. Flynn, Urology Handbook for Medical Students, 1, eKindle, self, 2017, 0-88pp, Book, PUBLISHED

  


Award Date
RCSI Travelling Fellowship 2011
Ethicon Travelling Fellowship 2011
Irish Society of Urology Medal 2010
RCSI-Ipsen-Anthony Walsh Travelling Fellowship 2008
I have an interest in technology and endourology, in particular, renal stone disease and benign prostate hyperplasia. My other research interests are in prostate cancer, both at molecular and clinical level with involvement in laboratory and clinical research in the area.