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Trinity College Dublin

Personal Information
College Photo Name Williams, David Clive
Main Department Biochemistry
College Title Professor of Chemical Biology
E-mail clive.williams@tcd.ie
College Tel +353 1 896 1855
Web http://www.tcd.ie/Biochemistry/research/c_williams.php
Fax +353 1 677 2400
 
Representations
Details Date
Member and sometime Chair of The National Committee for Biochemistry 1993-96,00-03
Secretary and Member of The Neurochemical Group Committee of The Biochemical Society 1990-95
Member of HRB Mental Health and Neurology, and Post-doctoral Fellowship Research Grants Committees 1991-2
Trustee of The Irish Area Section of The Biochemical Society FEBS Fund for Graduate students 1987-92
External examiner for research degrees in St Andrews, Leeds, Cardiff, Galway, Cork, Aarhus, etc
More Representations>>>
 
Membership of Professional Institutions, Associations, Societies
Details Date From Date To
Member of the Society for Neuroscience 2000
Member and Council Member of European Society for Neurochemistry 1990
Member of The International Society for Neurochemistry 1990
Royal Irish Academy 1995
The Biochemical Society 1970
 
Awards and Honours
Award Date
Elected Fellow of Trinity College 1987
Elected To Membership of Royal Irish Academy 1995
 
Description of Research Interests
Current Research Interests and Projects
 
Research Interests
5-HYDROXYTRYPTAMINE UPTAKE ANTIDEPRESSANT DRUGS ANTIPROLIFERATIVE ACTION APOPTOSIS
BCR-ABL BENZODIAZEPINE BINDING-SITES BENZODIAZEPINES CANCER
CASPASES CELL CYCLE CELL PROLIFERATION CHOLESTEROL
Computational Biology DIFFERENTIATION ESTROGEN-RECEPTOR GABA TRANSPORTER
INSECTICIDES Immunology, Immunotherapy In Vitro Testing, Trial Methods L-GLUTAMATE TRANSPORTER
LIGAND MITOCHONDRIA Molecular Biology PERIPHERAL-TYPE BENZODIAZEPINE BINDING SITE
PYRROLO-1,5-BENZOXAZEPINES PYRROLO-1,5-BENZOXAZEPINES INDUCE APOPTOSIS RECEPTOR LIGANDS RECEPTORS
SEROTONIN TRANSPORTER Structural Biology, Determination, Function
 
Publications and Other Research Outputs
Peer Reviewed
McGee, MM, Gemma, S, Rammunno, A, Zisterer,DM, Fatterusso, C, Catalanotti, B, Butini, S, Fiorini,I, Pisano, C, Cucco, C, Novellino, E, Nacci, V, Williams, DC and Campiani, G, Pyrolo [1,5] benzoxathiazepines as a new class of potent apoptotic agents. Biological studies and identification of an intracellular location of their drug target., Journal of Medicinal Chemistry, 48, (13), 2005, p4367 - 4377
Notes: [PMID: 15974589]
DOI  URL
SCANLON, SM, WILLIAMS, DC, SCHLOSS, P, MEMBRANE CHOLESTEROL MODULATES SEROTONIN TRANSPORTER ACTIVITY, BIOCHEMISTRY, 40, 2001, p10507 - 10513
WOODS, MJ, WILLIAMS, DC, MULTIPLE FORMS AND LOCATIONS FOR THE PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR, BIOCHEMICAL PHARMACOLOGY, 52, 1996, p1805 - 1814
PHILLIPS, OM, WOOD, KM, WILLIAMS, DC, KINETICS OF THE INTERACTION OF SERTRALINE WITH THE HUMAN-PLATELET PLASMA-MEMBRANE 5-HYDROXYTRYPTAMINE CARRIER, EUROPEAN JOURNAL OF PHARMACOLOGY, 146, 1988, p299 - 306
PHILLIPS, OM, WILLIAMS, DC, MULTIPLE AFFINITY STATES FOR [H-3]IMIPRAMINE BINDING-SITES ON HUMAN-PLATELET MEMBRANES, EUROPEAN JOURNAL OF PHARMACOLOGY, 100, 1984, 247 - 248
 
Non Peer Reviewed
Moynagh, P.N., O'Neill, L.A.J. & Williams, D.C., Modulation of the peripheral-type benzodiazepine acceptor by IL-1 and PMA, Neurochem. Int., 21, 1992, pC63
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Last Updated:22-AUG-2014