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- Leukocyte biology: functional studies on human leukocytes with a particular interest in “innate lymphocytes” (natural killer cells, CD1-restricted T cells and gamma delta T cells) and dendritic cells.
- Immunology of the human liver: examination of the healthy liver as a specialised organ of the immune system and investigation of immune mechanisms that contribute to pathologies associated with hepatitis B, hepatitis C, hepatic malignancies and autoimmune liver diseases
- Immunology and genetics of human disease: including rheumatoid arthritis, systemic lupus erythematosus, cystic fibrosis, alpha-1-antitrypsin deficiency, primary antiphospholipid syndrome and schizophrenia
- Teaching: course design, delivery and assessment of undergraduate level immunology, biochemistry, physiology, genetics and cell biology, co-director of an MSc programme in Immunology and Global Health at NUI Maynooth, research supervisor and examiner at BSc, MSc, PhD and MD levels, author of textbook chapters.
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Oliveira AL, Hayakawa H, Schor D, Leite AC, Espíndola OM, Waters A, Dean J, Doherty DG, Araújo AQ, Hall WW, High frequencies of functionally competent circulating Tax-specific CD8+ T cells in human T lymphotropic virus type 2 infection., Journal of Immunology, 183, 2009, p2957-2965
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Lynch L, O'Shea D, Winter DC, Geoghegan J, Doherty DG, O'Farrelly C, Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity., European Journal of Immunology, 39, (7), 2009, p1893-1901
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Rosen, HR, Doherty, DG, Madrigal-Estebas, L, O'Farrelly, C, Golden-Mason, L, Pretransplantation CD56(+) innate lymphocyte populations associated with severity of hepatitis C virus recurrence., Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 14, (1), 2008, p31 - 40
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Golden-Mason, L, Madrigal-Estebas, L, McGrath, E, Conroy, MJ, Ryan, EJ, Hegarty, JE, O'Farrelly, C, Doherty, DG, Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure., Gut, 57, (8), 2008, p1121-8
Notes: [PMID: 18372499]
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Kenna, T, O'Brien, M, Hogan, AE, Exley, MA, Porcelli, SA, Hegarty, JE, O'Farrelly, C, Doherty, DG, CD1 expression and CD1-restricted T cell activity in normal and tumour-bearing human liver., Cancer immunology, immunotherapy : CII, 56, (4), 2007, p563-72
Notes: [PMID: 16924493 ]
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