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Trinity College Dublin

Personal Information
College Photo Name Boylan, Fabio
Main Department Pharmacy
College Title Assistant Professor
E-mail fabio.boylan@tcd.ie
College Tel +353 1 896 4154
 
Biography
Born in Rio de Janeiro, Brazil, in 15 of February of 1972. Fabio Boylan studied Pharmacy at Rio de Janeiro Federal University, in Rio de Janeiro, Brazil. From February 1996 to February 1998, he was Lecturer at the Department of Pharmacognosy, Faculdade de Farmacia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil. His Master project "Phylogenetic Trends within Lamiiflorae" was sponsored by CNPq, a Brazilian Governmental Agency for 1.5 years and he got the degree after being evaluated by Dr. Otto Richard Gottlieb. His Ph.D. project “Chemical and Pharmacological Studies on Raphiodon echinus and Marsypianthes chamaedrys” was sponsored by CAPES, another Brazilian Governmental Agency. In several years he was awarded with grants from FAPERJ (Rio de Janeiro Research Supporting Agency) and FINEP in 2003 when he had the opportunity to chair the XII Italian-Latin-American Conference on Ethnomedicine. Also in 2003 he was awarded with a special grant from CNPq due to his scientific collaboration to the Brazilian Science. Fabio stepped up as a senior lecturer at the Faculty of Pharmacy, Federal University of Rio de Janeiro in 1998. In 2006, he started his sabbatical year in the School of Pharmacy and Pharmaceutical Sciences, TCD, where he further served as a research coordinator from 2007-2008 and now is a full time lecturer in Pharmacognosy. He acts an ad hoc reviewer for the following scientific journals: Brazilian Journal of Pharmacognosy, Brazilian Journal of Medicinal Plants, Brazilian Journal of Microbiology, Brazilian Journal of Pharmaceutical Sciences, Phytochemistry, Iheringia Zoologia (Section Botany), Phytotherapy Research, Current Medicinal Chemistry, African Journal of Pharmacology and Pharmaceutical Sciences.
 
Membership of Professional Institutions, Associations, Societies
Details Date From Date To
Phytochemical Society of North America 1992
Brazilian Society of Pharmacognosy 2000
 
Awards and Honours
Award Date
Cum Laude Diploma 1992
 
Languages
Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
French Fluent Basic Medium
Italian Fluent Medium Medium
Portuguese Fluent Fluent Fluent
Spanish Fluent Medium Medium
 
Description of Research Interests
MAJOR AREAS OF RESEARCH INTEREST AND ON-GOING INVESTIGATIONS: i) Chemical and Pharmacological study of Brazilian Palms; ii) Chemotaxonomic studies into Lamiiflorae; iii) Pharmaceutical Technology and Toxicology of Natural Products (collaborators: Dr. Françoise Nielloud, Université de Montpellier I and Dr. Laurance Vian, Université de Montpellier, France); iv) Evaluation of metabolites in Asteraceae species (Collaborator: Prof. Dra. Nunziatina di Tommasi, Universidade di Studi di Salerno, Italy); Chemical and Pharmacological study of different Bauhinia species for inflammation and diabetes (collaborators: Dr. Neil Frankish, School of Pharmacy and Pharmaceutical Sciences, TCD, Dublin Ireland and Dra. Helen Sheridan, School of Pharmacy and Pharmaceutical Sciences, TCD, Dublin, Ireland)
 
Research Interests
Antiinflammatory drugs Biochemistry, metabolism Chemistry of drug metabolism Chemistry of drug receptor interactions
Development of drugs for malaria, Cancer and inflammatory diseases Drug development Drug discovery Herbal medicine
Medicinal Chemistry Medicinal plants Microencapsulation methodologies Molecular markers and recognition
Molecular systematics Organic chemistry Pharmaceutical products Pharmacognosy
Pharmacological Sciences Phytochemical and pharmacological evaluations of native and foreign plants Phytomedicines Plant Biochemistry
Plant and algal cell monocultures Plant biology Plant systematics Plant tissue culture
Secondary plant metabolism Traditional and Indigenous health systems in developing countries
 
Research Projects
Project title Orbignya speciosa (Arecacea) as a potencial source of novel therapeutic agents: from traditional medicine information to the pharmacological evaluation of its chemical constituents.
Summary The aim of this project is to check the validity of the ethnopharmacological information for Orbignya speciosa in folk medicine. This plant is used, among other purposes, for the treatment of leukaemia and inflammatory conditions. Using modern techniques of isolation and purification of natural products and up-to-date spectroscopy techniques we aim to isolate the constituents responsible for such activities. It is also intended to test the activity for the extracts and isolates using in vivo (mice) and in vitro (cell culture) methodologies, allied to techniques in molecular pharmacology: DNA-fragmentation, electrophoresis, zymography, western-blot, apoptosis studies (flow cytometry), microscopy (SEM) among others.
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Publications and Other Research Outputs
Peer Reviewed
Menezes, F.S., Minto, A.B.M.. Ruella, H.S., Kuster, R.M., Sheridan, H., Frankish, N., Hypoglycemic activity of two Brazilian Bauhinia species: Bauhinia forficata L. and Bauhinia monandra Kurz., Brazilian Journal of Pharmacognosy, 17, (1), 2007, p14 - 18
MATHEUS, Maria Eline ; FERNANDES, Sidnei Bessa de Oliveira ; SILVEIRA, Cristiane Silva ; RODRIGUES, Verônica Pinto ; MENEZES, F. S. ; FERNANDES, Patrícia Dias, Inhibitory effects of partitions from Euterpe oleracea Mart. on nitric oxide production., Journal of Ethnopharmacology, 107, 2006, p291 - 296
DOI
FALCÃO, Deborah Quintanilha ; COSTA, Edlaine Rijo ; ALVIANO, Daniela Sales ; ALVIANO, Celuta Sales ; KUSTER, Ricardo Machado ; MENEZES, F. S. , Antioxidant and Anti-Microbial Activity from Calceolaria chelidonioides Humb. Bonpl. & Kunth. , Brazilian Journal of Pharmacognosy, 16, (1), 2006, p73 - 76
Falcão, DQ; Costa, ER; Menezes, FS; Kuster, RM., Ethnopharmacological study of plants used topically by the community of Macabú (RJ) and its essential oil chemistry evaluation , Brazilian Journal of Medicinal Plants, 8, 2006, p172 - 174
Reis, GM; Silveira, CS; Pessanha, CM; Menezes, FS; Kaplan, MAC; Fernandes, PD; Matheus, ME., Pharmacological study of Syagrus oleraceae (Martius) Beccari and Mauritia vinifera Martius fruit extracts, Brazilian Journal of Medicinal Plants, 8, 2006, p144 - 150
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Last Updated:01-SEP-2014