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Professor Yuri Volkov

Professor of Molecular & Translational M (Clinical Medicine)

Professor of Molecular & Translational M (Molecular Medicine Ireland)

Prof. Yuri Volkov received his MD from the Moscow Medical University and subsequently a PhD in biomedical sciences at the Institute of Immunology, Moscow. He has been working at the Department of Clinical Medicine, Trinity College Dublin since 1995. His research interests for a number of years have been focused in leukocyte biology, mechanisms of inflammation and cell adhesion receptors functioning in immune defence and disease development. Among the main achievements in this area was the discovery and characterization of the crucial impact of intracellular phosphorylation enzyme of the protein kinase C family - PKC-beta for the process of T cell migration. Success of these studies has been made possible through the implementation of the cutting edge High Content Screening Analysis (HCSA) cell and molecular imaging technologies. As a Principal Investigator at the Institute of Molecular Medicine, Prof. Volkov has made a key contribution into establishing of the HCSA Centre in Trinity College which represents a state-of-the art facility in the academic institution at the international level. Prof. Volkov has formed a large-scale interdisciplinary alliance between the Schools of Medicine, Physics, and Chemistry at Trinity College aimed at the development of new nanoscale molecular imaging and drug delivery systems. Prof. Volkov is also a Principal Investigator at the Trinity College's Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), where his group is pursuing the applications of nanomaterials for advanced research and medical diagnostics. Prof. Volkov currently coordinates a large scale EU FP-7 funded Consortium "NAMDIATREAM" (www. which unites the expertise of 22 European academic, research, clinical and industrial partners towards the development of nanotechnological toolkits for early diagnostics and treatment monitoring of major types of cancer. He is also a Lead TCD partner for EU FP-7 LSP "MULTIFUN" and "Celtic Alliance for Nanohealth" Ireland-Wales INTERREG Consortium.
  Bioengineering   Biomedical applications of nanotechnology   Cell migration & imaging   Diagnostics   Imaging Techniques   Immune system   Immunotherapies   Inflammation   INTEGRIN   INTEGRINS   Live cell imaging & high throughput (content) screening   Medical Devices   Nano Biotechnology   Nanomedicine   Nanotechnology
 Amber-Platform D Enhanced Capability
 NANOINTERACT - "Nanoparticle interactions with live cells, organelles and extracellular structures"
 Multifun - Bifunctional nanoparticles for cancer treatment
 Celtic Alliance for Nanohealth

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American Chemical Society 2011
Di Cristo, L. and Maguire, C.M. and Mc Quillan, K. and Aleardi, M. and Volkov, Y. and Movia, D. and Prina-Mello, A., Towards the identification of an in vitro tool for assessing the biological behavior of aerosol supplied nanomaterials, International Journal of Environmental Research and Public Health, 15, (4), 2018, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
Mohamed BM, Boyle NT, Schinwald A, Murer B, Ward R, Mahfoud OK, Rakovich T, Crosbie-Staunton K, Gray SG, Donaldson K, Volkov Y, Prina-Mello A., Induction of protein citrullination and auto-antibodies production in murine exposed to nickel nanomaterials., Scientific Reports, 8, (679), 2018, Journal Article, PUBLISHED  TARA - Full Text  URL
Marassi V, Di Cristo L, Smith SGJ, Ortelli S, Blosi M, Costa AL, Reschiglian P, Volkov Y, Prina-Mello A., Sliver nanoparticles as a medical device in healthcare settings: a five-step approach for candidate screening of coating agents, Royal Society Open Science, 5, (1), 2018, p171113-, Journal Article, PUBLISHED  TARA - Full Text  URL  URL
Adriele Prina-Mello, Namrata Jain, Baiyun Liu, Jason I. Kilpatrick, Melissa A. Tutty, Alan P. Bell, Suzanne P Jarvis, Yuri Volkova, Dania Movia, Culturing substrates influence the morphological, mechanical and biochemical features of lung adenocarcinoma cells cultured in 2D or 3D, Tissue and Cell, 50, 2018, p15 - 30, Journal Article, PUBLISHED  DOI
Hutchinson D, Muller J, McCarthy JE, Gun'ko YK, Verma NK, Bi X, Di Cristo L, Kickham L, Movia D, Prina-Mello A, Volkov Y, Cadmium nanoparticles citrullinate cytokeratins within lung epithelial cells: cadmium as a potential cause of citrullination in chronic obstructive pulmonary disease, International Journal of Chronic Obstructive Pulmonary Disease , 13, 2018, p441 - 449, Journal Article, PUBLISHED  TARA - Full Text  URL  URL
Marassi, Valentina and Di Cristo, Luisana and Smith, Stephen G J and Ortelli, Simona and Blosi, Magda and Costa, Anna L and Reschiglian, Pierluigi and Volkov, Yuri and Prina-Mello, Adriele, Silver nanoparticles as a medical device in healthcare settings: a five-step approach for candidate screening of coating agents, Royal Society open science, 5, (1), 2018, p171113 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Clarke, G. and Rogov, A. and McCarthy, S. and Bonacina, L. and Gun'Ko, Y. and Galez, C. and Le Dantec, R. and Volkov, Y. and Mugnier, Y. and Prina-Mello, A., Preparation from a revisited wet chemical route of phase-pure, monocrystalline and SHG-efficient BiFeO3nanoparticles for harmonic bio-imaging, Scientific Reports, 8, (1), 2018, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
Adriele Prina-Mello and Dania Movia and Despina Bazou and Yuri Volkov and Adriele Prina-Mello, Multilayered Cultures of NSCLC cells grown at the Air-Liquid Interface allow the efficacy testing of inhaled anti-cancer drugs, Scientific Reports, 2018, p12920-, Journal Article, PUBLISHED  TARA - Full Text  DOI
Ajetunmobi A, McAllister D, Jain n, Brazil O, Corvin A, Volkov Y, Tropea D, Prina-Mello A., Characterization of SH-SY5Y human neuroblastoma cell growth over glass and SU-8 substrates., Journal of Biomedical Materials Research, 105A, (8), 2017, p2129 - 2138, Journal Article, PUBLISHED  URL
Kuznetsova VA, Visheratina AK, Ryan A, Martynenko IV, Loudon A, Maguire CM, Purcell-Milton F, Orlova AO, Baranov AV, Fedorov AV, Prina-Mello A, Volkov Y, Gun'Ko YK., Enantioselective cytotoxicity of ZnS:Mn quantum dots in A549 cells., Chirality, 2017, p403-408 , Journal Article, PUBLISHED  DOI

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Nowostawska M., Corr S.A., Byrne S.J., Volkov Y., Gun'ko T.K. , Porphyrin-magnetite nanoconjugates for biological imaging, Journal of Nanobiotechnology, 9, (1), 2011, p1 , Journal Article, PUBLISHED
Santos-Martinez, M.J., Medina, C., Prina-Mello, A., Conroy, J., Samuels, S.P., Volkov, Y., Radomski, M.W., Nanobalance: a novel method for the measurement of flow-induced platelet aggregation, Nanomedicine: Seminar and Workshop, Centre for Research on Nanostructures and Nanodevices Trinity College Dublin, 29 June 2009, 2009, Poster, PUBLISHED
Verma N.K., Davies A.M., Long A., Kelleher D., Volkov Y., Selective inhibition of Stat3 expression induces apoptosis in human cutaneous T-lymphoma cell line Hut78, EJC Supplements, 20th EORTC-NCI-AACR Symposium on molecular targets and cancer therapeutics, Geneva, Switzerland, 21-24 October, 6, (12), Pergamon-Elsevier Science LTD, 2008, pp118 , Conference Paper, PUBLISHED
McCarthy J.E., Whelan D.M., Davies G.L., Byrne F., Conroy J., Volkov Y., Gun'ko Y., Fabrication and characterisation of photonic nanowires, Conference on Nanophotonic Materials, San Diego, CA, 10-12 August, edited by Gaburro Z, Cabrini S, Talapin D , 7030, SPIE-INT Soc Optical Engineering, 2008, pp3019 , Conference Paper, PUBLISHED
Prina-Mello A., Byrne F., Coey J.M.D., Mohamed B.M., Davies A., Volkov Y., High content screening investigation of nanomaterial toxicological response to proliferating MC3T3-E1 osteoblast cells: a time course study. , Proceedings of the Scientific and Clinical Applications of Magnetic Carriers, Vancouver, Canada, May, edited by Hafeli, Schutt, Zborowski , 2008, pp49 , Conference Paper, PUBLISHED
Whelan A.M., McCarthy J.E., Byrne F., Dowd F., Prina-Mello A., Coey J.M.D., Volkob Y., Gun'ko Y., Novel magnetic nanowires for cell labelling, 7th International conference on the Scientific and Clinical Applications of Magnetic Carriers, Vancouver, Canada, May, edited by Hafeli, Schutt, Zborowski , 2008, pp212 , Conference Paper, PUBLISHED
Dempsey E., Long A., Kelleher D., Volkov Y., LFA-1 dependent gene regulation during T cell migration, Keystone Symposia, Colorado, USA, 2008, Meeting Abstract, PUBLISHED
Spiers J.P., Edwards C., Rietz A., Jan E., Mulcahy F., Hennessy M., Volkov Y., Davies A.M., Protease inhibitor-induced cardiotoxicity: direct effects on cell viability and intracellular calcium levels, Ninth International Congress on Drug Therapy in HIV Infection, Glasgow, 9-13 November, 2008, Meeting Abstract, PUBLISHED
Rakovich Y.P., Gun'ko Y., Gaponik N., Rogach A.L., Volkov Y., Donegan J.F., Highly emissive CdTe nanowires grown in a phosphate buffer solution: Flim imaging and spectroscopic studies, ICONO Conference, Minsk, Byelarus, May 28 - 1 June, edited by Aktsipetrov OA, Shalaev SV, Gaponenko SV, Zheludev NI , 6728, SPIE-INT Soc Optical Engineering, 2007, pp72805 , Conference Paper, PUBLISHED
Zheng C.X., Long A., Volkov Y., Davies A., Kelleher D., Ahmad K., A cross-modal system for cell migration image annotation and retrieval, International Joint Conference on Neural Networks, Orlando, Florida, 12-17 August, Vols 1-6, 2007, pp1738 - 1743, Conference Paper, PUBLISHED


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Award Date
F.T.C.D Fellow of Trinity College Dublin 2010
Professor Yuri Volkov is the Director of Research of the School of Medicine. His personal interests include nanomedicine and biomedical applications of nanotechnologies, molecular mechanisms of immune system functioning in health and disease, cell adhesion and migration in inflammation and cancer, intracellular signalling and cytoskeletal dynamics, advanced cell and molecular imaging.