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Dr. Paula Murphy

Associate Professor (Zoology)
ZOOLOGY BUILDING


Paula Murphy's research interests are in the genetic regulation of embryonic development, and she has been carrying out research in this field since starting postgraduate studies towards her doctoral degree in 1987. The relationship between gene expression patterns and gene function has been a prominent part of her work, and detailed expression analysis is one of her specialisations. She currently focuses this interest on development of the limbs and facial region of vertebrate embryos.
  3d Imaging   Developmental Biology   Embryology   Expression Analysis   Genetics   In Situ Hybridisation   Morphogenesis   Wnt Signalling Pathway
Rolfe RA, Nowlan NC, Kenny EM, Cormican P, Morris DW, Prendergast PJ, Kelly D, Murphy P., Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways., BioMedCentral Genomics, 15, 2014, p1 - 23, Journal Article, PUBLISHED  TARA - Full Text
Mc Laughlin D, Murphy P, Puri P, Altered Tbx1 gene expression is associated with abnormal oesophageal development in the adriamycin mouse model of oesophageal atresia/tracheo-oesophageal fistula., Paediatric Surgery International, 30, (2), 2014, p143 - 149, Journal Article, PUBLISHED
Rolfe Rebecca, Roddy Karen, and Murphy Paula, Mechanical Regulation of Skeletal Development , Current Osteoporosis Reports, 11, (2), 2013, p107 - 116, Journal Article, PUBLISHED
Mc Laughlin, Danielle, Hajduk, Piotr, Murphy, Paula, Puri, Prem, Adriamycin-Induced Models of VACTERL Association, Molecular Syndromology, 4, (1-2), 2013, p46 - 62, Journal Article, PUBLISHED  DOI
Wong, F., Welten, M.C.M., Anderson, C., Bain, A.A., Liu, J., Wicks, M.N., Pavlovska, G., (...), Burt, D.W., eChickAtlas: An introduction to the database, Genesis, 51, (5), 2013, p365-371 , Notes: [ ], Journal Article, PUBLISHED  DOI
Sato H, Hajduk P, Furuta S, Wakisaka M, Murphy P, Puri P, Kitagawa H, Effect of abnormal notochord delamination on hindgut development in the Adriamycin mouse model., Pediatric Surgery International , 29, (11), 2013, p1209 - 1216, Journal Article, PUBLISHED
Tatiana Vinardell, Rebecca A. Rolfe, Conor T. Buckley, Eric G. Meyer, Mark Ahearne, Paula Murphy and Daniel J. Kelly, Hydrostatic pressure acts to stabilise a chondrogenic phenotype in porcine joint tissue derived stem cells, european Cells and Materials, 23, 2012, p121 - 134, Journal Article, PUBLISHED
Martin, Audrey; Maher, Stephanie; Summerhurst, Kristen; Davidson, Duncan; Murphy, Paula , Differential deployment of Paralogous Wnt genes in the Mouse and Chick Embryo during Development. , Evolution and Development, 142, 2012, p178 - 196, Notes: [ PubMed ID: 23017026], Journal Article, PUBLISHED  DOI
Hajduk, Piotr; May, Alison; Puri, Prem; Murphy, Paula , The Effect of Adriamycin Exposure on the Notochord of Mouse Embryos, Birth Defects Research Part B: Developmental and Reproductive Toxicology , 95, 2012, p175 - 183, Notes: [ PubMed ID: 22311705], Journal Article, PUBLISHED  DOI
Nowlan, N.C., Dumas, G., Tajbakhsh, S., Prendergast, P.J., Murphy, P. , Biophysical stimuli induced by passive movements compensate for lack of skeletal muscle during embryonic skeletogenesis , Biomechanics and Modeling in Mechanobiology, 11, (1-2), 2011, p207-219 , Journal Article, PUBLISHED  TARA - Full Text
  

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Nowlan, N. C., P. Murphy & P. J. Prendergast. , The influence of mechanical forces in the growing embryonic limb. , Transactions of the 52nd Annual Meeting of the Orthopaedic Research Society, the 52nd Annual Meeting of the Orthopaedic Research Society, Chicago, Illinois, edited by Burr, D. B , 31, 2006, ppno. 123-, Conference Paper, PUBLISHED
Miller S.F., Runker A.E., Kerjan G., Friedel R.H., Murphy P., Mitchell K.J., TEM7R in the developing mammalian nervous system. , International Journal of Developmental Neuroscience , 24, 2006, p598 - 598, Journal Article, PUBLISHED

  

Award Date
Science Foundation Ireland. Investigator Programme Grant September 2003 - September 2007
Norwegian Cancer Society (Den Norske Kreftforening) research grants 1996, 1997, 1998, 1999
Human Frontiers Science Program fellowship 1993
EMBO long term research fellowship 1991
Medical Research Council Studentship 1988