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Professor John O'Leary

Professor Consultant (Histopathology)
SIR PATRICK DUN LAB

Professor Consultant (Molecular Medicine Ireland)

  Biomarkers of disease   Cervical Cancer   Development of array technologies   Molecular pathology   Prostate cancer
Details Date
Member, DMMC Cancer Principal Investigators, Trans-institutional grouping of Principal Investigators leading research on Cancer themes
Member, Core Technology PI's, DMMC Principal Investigators leading the development of core technology platforms.
Member, Centre for Molecular Research in Cancer (Proposed), This consortium combines researchers with common interest in understanding cell cycle signaling and regulation with specific focus on two key cancer-related processes (cell cycle control, apoptosis) and/or three specific malignancy types (oesophageal, prostate and haematological).
Invitee, Breast Cancer Consortium (Proposed), Investigators to be invited to participate in Breast Cancer workshop with a view to establishing formal consortium and informal individual collaborations.Last updated : 19 November 2004. Extract from DMMC Research Database
Steven Busschotsa, b, , Sharon O'Tooleb, , John J. O'Learya, b, , Britta Stordala, c, , , Carboplatin and taxol resistance develops more rapidly in functional BRCA1 compared to dysfunctional BRCA1 ovarian cancer cells, Experimental Cell Research, 2015, Journal Article, IN_PRESS  DOI
Busschots,Steven S., O'Toole,Sharon A. S.A., O'Leary,John James J.J., Stordal,Britta K. B.K., Non-invasive and non-destructive measurements of confluence in cultured adherent cell lines, MethodsX, 2, 2015, p8-13 , Journal Article, PUBLISHED  TARA - Full Text  DOI
O'Brien CP, Taylor SE, O'Leary JJ, Finn SP, Molecular testing in oncology: Problems, pitfalls and progress., Lung cancer (Amsterdam, Netherlands), 2014, Journal Article, PUBLISHED  TARA - Full Text
O'Brien CP, Langabeer SE, O'Byrne KJ, O'Leary JJ, Finn SP, Predictive values for molecular diagnostics: converting unknown unknowns to known unknowns., Molecular diagnosis & therapy, 18, (1), 2014, p1-4 , Journal Article, PUBLISHED  DOI
Loy A, McInerney J, Pilkington L, Keegan H, Delamere S, Martin CM, Sheils O, O'Leary JJ, Mulcahy F., Human papillomavirus DNA and mRNA prevalence and association with cervical cytological abnormalities in the Irish HIV population., International Journal of Sexually Transmitted Diseases and AIDS, 2014, Journal Article, APPROVED
Laios A, Mohamed BM, Kelly L, Flavin R, Finn S, McEvoy L, Gallagher M, Martin C, Sheils O, Ring M, Davies A, Lawson M, Gleeson N, D'Arcy T, d'Adhemar C, Norris L, Langhe R, Saadeh FA, O'Leary JJ, O'Toole SA, Pre-Treatment of Platinum Resistant Ovarian Cancer Cells with an MMP-9/MMP-2 Inhibitor Prior to Cisplatin Enhances Cytotoxicity as Determined by High Content Screening., International journal of molecular sciences, 14, (1), 2013, p2085-103 , Journal Article, PUBLISHED  TARA - Full Text
Brosnan JF, Sheppard BL, Kelly LA, O'Leary JJ, Norris LA, Norethisterone acetate alters coagulation gene expression in vitro in human cell culture., Thrombosis research, 131, (1), 2013, p72 - 77, Journal Article, PUBLISHED
Tjalma WA, Fiander A, Reich O, Powell N, Nowakowski AM, Kirschner B, Koiss R, O'Leary J, Joura EA, Rosenlund M, Colau B, Schledermann D, Kukk K, Damaskou V, Repanti M, Vladareanu R, Kolomiets L, Savicheva A, Shipitsyna E, Ordi J, Molijn A, Quint W, Raillard A, Rosillon D, De Souza SC, Jenkins D, Holl K, Differences in human papillomavirus type distribution in high-grade cervical intraepithelial neoplasia and invasive cervical cancer in Europe., International journal of cancer. Journal international du cancer, 132, (4), 2013, p854-67 , Journal Article, PUBLISHED
Barr MP, Gray SG, Hoffmann AC, Hilger RA, Thomale J, O'Flaherty JD, Fennell DA, Richard D, O'Leary JJ, O'Byrne KJ., Generation and characterisation of Cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature., PloS one, 8, (1), 2013, pe54193 , Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Abu Saadeh, Norris L, O'Toole S, Mohamed BM, Langhe R, O'Leary J, Gleeson N, Tumour expresion of tissue factor and tissue factor pathway inhibitor in ovarian cancer- relationship with venous thrombosis risk., Thrombosis Research, 132, 2013, p627 - 634, Journal Article, PUBLISHED  DOI
  

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Abu Saadeh F, Norris L, O'Toole S, Langhe R, O'Leary JJ, Gleeson N., Does tissue factor and tissue factor pathway inhibitor over-expression play a role in the development of venous thromboembolism in ovarian cancer patients?, Thrombosis Research, 6th International Conference on Thrombosis & Hemostasis Issues in Cancer, Bergamo Italy, April 2012, edited by A Falanga, B. Brenner, F, Rickles , 129, ((Suppl 1)), Elsevier, 2012, Published Abstract, PUBLISHED
Abu Saadeh. F, Norris. L, O' Toole. S, Langhe. R, O' Leary. J, Gleeson. N. , Why is venous thromboembolism is a common complication of ovarian cancer? , International Journal of Gynecological Cancer , 14th Biennial Meeting of the International Gynecological Cancer Society. , Vancouver, Canada, October 2012, 22, (Suppl 3), 2012, Published Abstract, PUBLISHED
Abu Saadeh F, Norris L, O'Toole S, Langhe R, Gleeson N., Procoagulant activity in patients with gynecological malignancies and the effect of neoadjuvant chemotherapy , Thrombosis Research, 6th International Conference on Thrombosis & Hemostasis Issues in Cancer, Bergamo Italy, April 2012, edited by A Falanga, B. Brenner, F, Rickles , 129, (Suppl 1), Elsevier, 2012, Published Abstract, PUBLISHED
Abu Saadeh. F, Norris. L, O' Toole. S, Langhe. R, Gleeson. N, Endogenous thrombin potential as a marker for venous thrombosis in ovarian cancer., International Journal of Gynecological Cancer , 14th Biennial Meeting of the International Gynecological Cancer Society., Vancouver, Canada, October 2012, 22, (Suppl 3), 2012, Published Abstract, PUBLISHED

  

Biomarkers of disease. Cervical Cancer. Development of array technologies. Molecular pathology. Prostate cancer.