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Professor Cliona O'Farrelly

Chair in Comparative Immunology (Biochemistry)

 ofarrecl@tcd.ie

 3531896 3175

Chair in Comparative Immunology (Clinical Medicine)


Research Tags

  Animal Diseases/Pathology   Animal Reproductive Biology   Biomedical sciences   Chronic inflamation   Equine Diseases/Pathology   Food Safety   Hepatitis C   Host, Pathogen interactions   Human genetics   IMMUNE CELLS   Immune system   IMMUNE-MEDIATED   IMMUNOCOMPETENT CELLS   INFECTION   Infectious diseases   Infertility   INFLAMMATION   INNATE IMMUNE-SYSTEM   INNATE IMMUNITY   Innate immunology   Leukocyte Biology   Liver diseases and transplantation   Mucosal immunology   Poultry Products   Poultry Science   Reproduction, fertility and contraception   Stem Cell biology and hematopoiesis   Transplantation immunology, tolerance and rejection   Tumour immunology and immunotherapy   Vaccines   Virology and viral pathogenesis

Research Projects

 SFI Research Frontiers 2008 08/RFP/BMT1403
 HRB Project Grant 2007 RP/2007/278
 HRB Translational Research Award 2007 TRA/2007/14
 Dept. Agriculture Research Stimulus Fund 2006 06/340
 FIRM Grant 2006 06/RDD/486

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Languages

Language Skill Reading Skill Writing Skill Speaking
English Fluent Fluent Fluent
French Fluent Fluent Fluent
German Fluent Fluent Fluent

Memberships

Membership of Professional Institutions, Associations, Societies

Details Date From Date To
Irish Society of Immunology 1984 present
Harmon C, Robinson M.W, Hand F, Almuaili D, Mentor K, Houlihan D.D, Hoti E, Lynch L, Geoghegan J, O'Farrelly C, Lactate-Mediated Acidification of Tumor Microenvironment Induces Apoptosis of Liver-Resident NK Cells in Colorectal Liver Metastasis, Cancer immunology research, 7, (2), 2019, p335 - 346, Journal Article, PUBLISHED  DOI  URL
Meade, K.G. and O'Farrelly, C., Î'-Defensins: Farming the microbiome for homeostasis and health, Frontiers in Immunology, 10, (JAN), 2019, Notes: [cited By 1], Journal Article, PUBLISHED  TARA - Full Text  DOI
Kelly, P. and Meade, K.G. and O'Farrelly, C., Non-canonical inflammasome-mediated IL-1β production by primary endometrial epithelial and stromal fibroblast cells is NLRP3 and caspase-4 dependent, Frontiers in Immunology, 10, (FEB), 2019, p1--, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
*Galvin KC, *Conroy MJ, Doyle SL, Dunne MR, Fahey R, Foley E, O'Sullivan KE, Doherty DG, Geoghegan JG, Ravi N, O'Farrelly C, Reynolds JV, Lysaght J., Extratumoral PD-1 blockade does not perpetuate obesity-associated inflammation in esophageal adenocarcinoma., Cancer Letters, 418, 2018, p230-238 , Notes: [*JOINT FIRST AUTHORSHIP], Journal Article, PUBLISHED  DOI  URL
Glover, L.E. and Crosby, D. and Thiruchelvam, U. and Harmon, C. and Chorcora, C.N. and Wingfield, M.B. and O'Farrelly, C., Uterine natural killer cell progenitor populations predict successful implantation in women with endometriosis-associated infertility, American Journal of Reproductive Immunology, 2018, pe12817-, Notes: [cited By 0; Article in Press], Journal Article, PUBLISHED  DOI
Gargan, S. and Ahmed, S. and Mahony, R. and Bannan, C. and Napoletano, S. and O'Farrelly, C. and Borrow, P. and Bergin, C. and Stevenson, N.J., HIV-1 Promotes the Degradation of Components of the Type 1 IFN JAK/STAT Pathway and Blocks Anti-viral ISG Induction, EBioMedicine, 30, 2018, p203-216 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Adnane, M. and Kelly, P. and Chapwanya, A. and Meade, K.G. and O'Farrelly, C., Improved detection of biomarkers in cervico-vaginal mucus (CVM) from postpartum cattle, BMC Veterinary Research, 14, (1), 2018, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
Whiston, R. and Finlay, E.K. and McCabe, M.S. and Cormican, P. and Flynn, P. and Cromie, A. and Hansen, P.J. and Lyons, A. and Fair, S. and Lonergan, P. and O'Farrelly, C. and Meade, K.G., A dual targeted β-defensin and exome sequencing approach to identify, validate and functionally characterise genes associated with bull fertility, Scientific Reports, 7, (1), 2017, p12287 -, Notes: [cited By 0], Journal Article, PUBLISHED  TARA - Full Text  DOI
Garvey, P. and Murphy, N. and Flanagan, P. and Brennan, A. and Courtney, G. and Crosbie, O. and Crowe, J. and Hegarty, J. and Lee, J. and McIver, M. and McNulty, C. and Murray, F. and Nolan, N. and O'Farrelly, C. and Stewart, S. and Tait, M. and Norris, S. and Thornton, L., Disease outcomes in a cohort of women in Ireland infected by hepatitis C-contaminated anti-D immunoglobulin during 1970s, Journal of Hepatology, 67, (6), 2017, p1140-1147 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Adnane, M. and Chapwanya, A. and Kaidi, R. and Meade, K.G. and O'Farrelly, C., Profiling inflammatory biomarkers in cervico-vaginal mucus (CVM) postpartum: Potential early indicators of bovine clinical endometritis?, Theriogenology, 103, 2017, p117-122 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
  

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Orla Convery, Siobhan Gargan, Michelle Kickham, Martina Schroder, Cliona O'Farrelly and Nigel J. Stevenson, The hepatitis C virus (HCV) protein, p7, suppresses inflammatory responses to tumor necrosis factor (TNF)- a via signal transducer and activator of transcription (STAT)3 and extracellular signal-regulated kinase (ERK) - mediated induction of suppressor of cytokine signaling (SOCS)3, The FASEB Journal, Aug, 2019, p8732 - 8744, Journal Article, PUBLISHED
Orla Convery, Siobhan Gargan, Michelle Kickham, Martina Schroder, Cliona O'Farrelly and Nigel J. Stevenso, The hepatitis C virus (HCV) protein, p7, suppresses inflammatory responses to tumor necrosis factor (TNF)- a via signal transducer and activator of transcription (STAT)3 and extracellular signal-regulated kinase (ERK) - mediated induction of suppressor of cytokine signaling (SOCS)3, The FASEB Journal, Aug, 2019, p8732 - 8744, Journal Article, PUBLISHED
Innate immune mechanisms in the liver. in, editor(s)Gershwin ME, Vierling JM, Manns MP , Liver Immunology: Principles and Practices, New Jersey, Humana Press, 2007, pp41-48 , [O'Farrelly C, Doherty DG. ], Notes: [2nd edition], Book Chapter, PUBLISHED
A short primer on fundamental immunology in, editor(s)Gershwin ME, Vierling JM, Manns MP , Liver Immunology: Principles and Practices, New Jersey, Humana Press, 2007, pp15-24 , [O'Farrelly C, Doherty DG. ], Notes: [2nd edition], Book Chapter, PUBLISHED
Lymphocyte repertoires in healthy liver. in, editor(s)Gershwin ME, Vierling JM, Manns MP , Liver Immunology, Philadelphia, Hanley & Belfus, 2003, pp31-46 , [Doherty DG, O'Farrelly C.], Book Chapter, PUBLISHED

  

Awards and Honours

Award Date
Irish Society Immunology Public Lecture Award 2008
Isla Haliday Memorial Lecture 2004
Conway Lecturer and Medallist 2004
President, Irish Society of Immunology 2001-2007
Thomas Davis Lecturer 1999
Irish Research Scientists Association Gold Medal 1998
Grave's Lecturer and Medallist 1997
Fellow Royal Academy of Medicine of Ireland 1997