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Professor Michael Rowan

Professor of Neuropharmacology (Pharmacology & Therapeutics)

 Mechanisms of the synaptic plasticity disrupting actions of Aß
  Neurocardiovascular influences on cognitive functioning

Klyubin I, Ondrejcak T, Hayes J, Cullen WK, Mably AJ, Walsh DM, Rowan MJ, Neurotransmitter receptor and time dependence of the synaptic plasticity disrupting actions of Alzheimer's disease Aß in vivo., Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 369, (1633), 2014, p20130147 , Journal Article, PUBLISHED  DOI
An K, Klyubin I, Kim Y, Jung JH, Mably AJ, O'Dowd ST, Lynch T, Kanmert D, Lemere CA, Finan GM, Park JW, Kim TW, Walsh DM, Rowan MJ, Kim JH, Exosomes neutralize synaptic-plasticity-disrupting activity of Aß assemblies in vivo., Molecular brain, 6, 2013, p47 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Qi Y, Hu NW, Rowan MJ, Switching off LTP: mGlu and NMDA receptor-dependent novelty exploration-induced depotentiation in the rat hippocampus., Cerebral cortex (New York, N.Y. : 1991), 23, (4), 2013, p932-9 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Ondrejcak T, Wang Q, Kew JN, Virley DJ, Upton N, Anwyl R, Rowan MJ, Activation of α7 nicotinic acetylcholine receptors persistently enhances hippocampal synaptic transmission and prevents Aß-mediated inhibition of LTP in the rat hippocampus., European Journal of Pharmacology, 677, (1-3), 2012, p63 - 70, Journal Article, PUBLISHED  DOI
Neng-Wei Hu, Tomas Ondrejcak, Michael J. Rowan, Glutamate receptors in preclinical research on Alzheimer's disease: update on recent advances, Pharmacology, 100, (4), 2012, p855-862 , Journal Article, PUBLISHED  TARA - Full Text
Klyubin I, Cullen WK, Hu NW, Rowan MJ, Alzheimer's disease Aß assemblies mediating rapid disruption of synaptic plasticity and memory., Molecular brain, 5, 2012, p25 , Journal Article, PUBLISHED  TARA - Full Text  DOI
Barry, A.E., Klyubin, I., McDonald, J.M., Mably, A.J., Farrell, M.A., Scott, M., Walsh, D.M., Rowan, M.J., Alzheimer's disease brain-derived amyloid-ß-mediated inhibition of LTP In Vivo is prevented by immunotargeting cellular prion protein, Journal of Neuroscience, 31, (20), 2011, p7259-7263 , Journal Article, PUBLISHED  TARA - Full Text
Klyubin, I, Wang, Q, Reed, MN, Irving, EA, Upton, N, Hofmeister, J, Cleary, JP, Anwyl, R, Rowan, MJ, Protection against Abeta-mediated rapid disruption of synaptic plasticity and memory by memantine., Neurobiology of Aging, 32, 2011, p614 - 633, Journal Article, PUBLISHED  DOI
Freir DB, Nicoll AJ, Klyubin I, Panico S, Mc Donald JM, Risse E, Asante EA, Farrow MA, Sessions RB, Saibil HR, Clarke AR, Rowan MJ, Walsh DM, Collinge J, Interaction between prion protein and toxic amyloid ß assemblies can be therapeutically targeted at multiple sites., Nature Communications, 2, (336), 2011, Journal Article, PUBLISHED  TARA - Full Text
Lanté F, Toledo-Salas JC, Ondrejcak T, Rowan MJ, Ulrich D, Removal of Synaptic Ca2+-Permeable AMPA Receptors during Sleep., The Journal of Neuroscience , 31, (11), 2011, p3953-61 , Journal Article, PUBLISHED  TARA - Full Text

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