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Professor Michael Rowan

Professor of Neuropharmacology (Pharmacology & Therapeutics)

 Mechanisms of the synaptic plasticity disrupting actions of Aß
  Neurocardiovascular influences on cognitive functioning

Mitchell D.P, Rowan M, Loughman E, Ridge C.A, MacMahon P.J, Contrast monitoring techniques in CT pulmonary angiography: An important and underappreciated contributor to breast dose, European Journal of Radiology, 86, 2017, p184 - 189, Notes: [Export Date: 21 February 2017], Journal Article, PUBLISHED  DOI  URL
Zhang D, Jin B, Ondrejcak T, Rowan M.J, Opposite in vivo effects of agents that stimulate or inhibit the glutamate/cysteine exchanger system xcâ, ' on the inhibition of hippocampal LTP by AÃ , Hippocampus, 26, (12), 2016, p1655 - 1665, Notes: [Export Date: 21 February 2017], Journal Article, PUBLISHED  DOI  URL
Miller, A.M., Begley, E., Coen, R.F., Doyle, M., Dunne, J., Hutchinson, S., Kennelly, S.P., Kenny, R.A., Killeen, R.P., O'Dwyer, S., O'Neill, C., O'Sullivan, S.S., Rowan, M.J., Sheehy, N., McGuigan, C., Lawlor, B.A. , Clinical consensus guidelines on the application of cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: recommendations of the Irish Network for Biomarkers in Neurodegeneration., Irish Medical Journal, 109, (10), 2016, p1-13 , Journal Article, PUBLISHED
Chang L, Cui W, Yang Y, Xu S, Zhou W, Fu H, Hu S, Mak S, Hu J, Wang Q, Pui-Yan Ma V, Chung-Lit Choi T, Dik-Lung Ma E, Tao L, Pang Y, Rowan M.J, Anwyl R, Han Y, Wang Q, Protection against ß-amyloid-induced synaptic and memory impairments via altering ß-amyloid assembly by bis(heptyl)-cognitin, Scientific Reports, 5, 2015, p10256-, Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Levites Y, O-Nuallain B, Puligedda R.D, Ondrejcak T, Adekar S.P, Chen C, Cruz P.E, Rosario A.M, Macy S, Mably A.J, Walsh D.M, Vidal R, Solomon A, Brown D, Rowan M.J, Golde T.E, Dessain S.K, A human monoclonal IgG that binds Aß assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo, Journal of Neuroscience, 35, (16), 2015, p6265 - 6276, Notes: [Export Date: 27 August 2015], Journal Article, PUBLISHED  DOI  URL
Harte NP, Klyubin I, McCarthy EK, Min S, Garrahy SA, Xie Y, Davey GP, Boland JJ, Rowan MJ, Mok KH, Amyloid Oligomers and Mature Fibrils Prepared from an Innocuous Protein Cause Diverging Cellular Death Mechanisms., The Journal of biological chemistry, 290, (47), 2015, p28343 - 28352, Journal Article, PUBLISHED  TARA - Full Text  DOI
O'Malley, T.T. Oktaviani, N.A. Zhang, D. Lomakin, A. O'Nuallain, B. Linse, S. Benedek, G.B. Rowan, M.J. Mulder, F.A.A. Walsh, D.M., Aß dimers differ from monomers in structural propensity, aggregation paths and population of synaptotoxic assemblies, Biochemical Journal, 461, (3), 2014, p413 - 426, Notes: [Cited By :1 Export Date: 4 March 2015], Journal Article, PUBLISHED  DOI  URL
Hu, N.-W. Nicoll, A.J. Zhang, D. Mably, A.J. O'Malley, T. Purro, S.A. Terry, C. Collinge, J. Walsh, D.M. Rowan, M.J., MGlu5 receptors and cellular prion protein mediate amyloid-ß- facilitated synaptic long-term depression in vivo, Nature Communications, 5, 2014, Notes: [Cited By :2 Export Date: 4 March 2015], Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Welzel, A.T. Maggio, J.E. Shankar, G.M. Walker, D.E. Ostaszewski, B.L. Li, S. Klyubin, I. Rowan, M.J. Seubert, P. Walsh, D.M. Selkoe, D.J., Secreted amyloid ß-proteins in a cell culture model include N-terminally extended peptides that impair synaptic plasticity, Biochemistry, 53, (24), 2014, p3908 - 3921, Notes: [Export Date: 4 March 2015], Journal Article, PUBLISHED  TARA - Full Text  DOI  URL
Klyubin, I. Nicoll, A.J. Khalili-Shirazi, A. Farmer, M. Canning, S. Mably, A. Linehan, J. Brown, A. Wakeling, M. Brandner, S. Walsh, D.M. Rowan, M.J. Collinge, J., Peripheral administration of a humanized anti-PrP antibody blocks Alzheimer's disease Aß synaptotoxicity, Journal of Neuroscience, 34, (18), 2014, p6140 - 6145, Notes: [Cited By :3 Export Date: 4 March 2015], Journal Article, PUBLISHED  TARA - Full Text  DOI  URL

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