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Professor Michael Rowan

Professor of Neuropharmacology (Pharmacology & Therapeutics)

Professor of Neuropharmacology (Trinity Inst. of Neurosciences (TCIN))

 Mechanisms of the synaptic plasticity disrupting actions of Aß
  Neurocardiovascular influences on cognitive functioning

O'Riordan, K.J. and Hu, N.-W. and Rowan, M.J., Physiological activation of mGlu5 receptors supports the ion channel function of NMDA receptors in hippocampal LTD induction in vivo, Scientific Reports, 8, (1), 2018, Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Balschun, D. and Rowan, M.J., Hippocampal synaptic plasticity in neurodegenerative diseases: AÃ , tau and beyond, Neuroforum, 2018, Notes: [cited By 0; Article in Press], Journal Article, PUBLISHED  DOI
Qi, Y. and Klyubin, I. and Claudio Cuello, A. and Rowan, M.J., NLRP3-dependent synaptic plasticity deficit in an Alzheimer's disease amyloidosis model in vivo, Neurobiology of Disease, 114, 2018, p24-30 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Hu, N.-W. and Corbett, G.T. and Moore, S. and Klyubin, I. and O'Malley, T.T. and Walsh, D.M. and Livesey, F.J. and Rowan, M.J., Extracellular Forms of Aβ and Tau from iPSC Models of Alzheimer's Disease Disrupt Synaptic Plasticity, Cell Reports, 23, (7), 2018, p1932-1938 , Notes: [cited By 1], Journal Article, PUBLISHED  DOI
O'Riordan, K.J. and Hu, N.-W. and Rowan, M.J., AÃ Facilitates LTD at Schaffer Collateral Synapses Preferentially in the Left Hippocampus, Cell Reports, 22, (8), 2018, p2094-2106 , Notes: [cited By 1], Journal Article, PUBLISHED  DOI
Zhang, D. and Qi, Y. and Klyubin, I. and Ondrejcak, T. and Sarell, C.J. and Cuello, A.C. and Collinge, J. and Rowan, M.J., Targeting glutamatergic and cellular prion protein mechanisms of amyloid β-mediated persistent synaptic plasticity disruption: Longitudinal studies, Neuropharmacology, 121, 2017, p231-246 , Notes: [cited By 0], Journal Article, PUBLISHED  DOI
Zhang, D. and Mably, A.J. and Walsh, D.M. and Rowan, M.J., Peripheral Interventions Enhancing Brain Glutamate Homeostasis Relieve Amyloid β- A nd TNFα-Mediated Synaptic Plasticity Disruption in the Rat Hippocampus, Cerebral Cortex, 27, (7), 2017, p3724-3735 , Notes: [cited By 1], Journal Article, PUBLISHED  DOI
Miller, A.M., Begley, E., Coen, R.F., Doyle, M., Dunne, J., Hutchinson, S., Kennelly, S.P., Kenny, R.A., Killeen, R.P., O'Dwyer, S., O'Neill, C., O'Sullivan, S.S., Rowan, M.J., Sheehy, N., McGuigan, C., Lawlor, B.A. , Clinical consensus guidelines on the application of cerebrospinal fluid biomarkers for Alzheimer's disease diagnosis: recommendations of the Irish Network for Biomarkers in Neurodegeneration., Irish Medical Journal, 109, (10), 2016, p1-13 , Journal Article, PUBLISHED
Zhang D, Jin B, Ondrejcak T, Rowan M.J, Opposite in vivo effects of agents that stimulate or inhibit the glutamate/cysteine exchanger system xcâ, ' on the inhibition of hippocampal LTP by AÃ , Hippocampus, 26, (12), 2016, p1655 - 1665, Notes: [Export Date: 21 February 2017], Journal Article, PUBLISHED  DOI  URL
Harte NP, Klyubin I, McCarthy EK, Min S, Garrahy SA, Xie Y, Davey GP, Boland JJ, Rowan MJ, Mok KH, Amyloid Oligomers and Mature Fibrils Prepared from an Innocuous Protein Cause Diverging Cellular Death Mechanisms., The Journal of biological chemistry, 290, (47), 2015, p28343 - 28352, Journal Article, PUBLISHED  TARA - Full Text  DOI

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